Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1
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Title
Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1
Authors
Keywords
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Journal
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
Volume 307, Issue 6, Pages E469-E484
Publisher
American Physiological Society
Online
2014-08-06
DOI
10.1152/ajpendo.00204.2014
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Note: Only part of the references are listed.- SMAD3 augments FoxO3-induced MuRF-1 promoter activity in a DNA-binding-dependent manner
- (2014) Lance M. Bollinger et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- p53 and ATF4 mediate distinct and additive pathways to skeletal muscle atrophy during limb immobilization
- (2014) Daniel K. Fox et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Atrogin-1 deficiency promotes cardiomyopathy and premature death via impaired autophagy
- (2014) Tania Zaglia et al. JOURNAL OF CLINICAL INVESTIGATION
- Noninvasive Imaging of In Vivo MuRF1 Expression during Muscle Atrophy
- (2014) Wei Li et al. PLoS One
- Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression
- (2014) Leslie M. Baehr et al. Frontiers in Physiology
- TWEAK/Fn14 Signaling Axis Mediates Skeletal Muscle Atrophy and Metabolic Dysfunction
- (2014) Shuichi Sato et al. Frontiers in Immunology
- Maintenance of muscle mass and load-induced growth in Muscle RING Finger 1 null mice with age
- (2013) Darren T. Hwee et al. AGING CELL
- Skeletal muscle denervation causes skeletal muscle atrophy through a pathway that involves both Gadd45a and HDAC4
- (2013) Kale S. Bongers et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Distinct responses of protein turnover regulatory pathways in hypoxia- and semistarvation-induced muscle atrophy
- (2013) Chiel C. de Theije et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Diggin′ on U(biquitin): A Novel Method for the Identification of Physiological E3 Ubiquitin Ligase Substrates
- (2013) Carrie E. Rubel et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- The role of ubiquitin ligases in cardiac disease
- (2013) Monte S. Willis et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Smad3 Induces Atrogin-1, Inhibits mTOR and Protein Synthesis, and Promotes Muscle Atrophy In Vivo
- (2013) Craig A. Goodman et al. MOLECULAR ENDOCRINOLOGY
- BMP signaling controls muscle mass
- (2013) Roberta Sartori et al. NATURE GENETICS
- Mechanisms and function of substrate recruitment by F-box proteins
- (2013) Jeffrey R. Skaar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Altered gene expression patterns in muscle ring finger 1 null mice during denervation- and dexamethasone-induced muscle atrophy
- (2013) J. David Furlow et al. PHYSIOLOGICAL GENOMICS
- Identification of atrogin-1-targeted proteins during the myostatin-induced skeletal muscle wasting
- (2012) Sudarsanareddy Lokireddy et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- The worsening of tibialis anterior muscle atrophy during recovery post-immobilization correlates with enhanced connective tissue area, proteolysis, and apoptosis
- (2012) Lamia Slimani et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- A cell-autonomous role for the glucocorticoid receptor in skeletal muscle atrophy induced by systemic glucocorticoid exposure
- (2012) Monica L. Watson et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- MAFbx, MuRF1, and the stress-activated protein kinases are upregulated in muscle cells during total knee arthroplasty
- (2012) Ashley N. Bailey et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- A Critical Role for Muscle Ring Finger-1 in Acute Lung Injury–associated Skeletal Muscle Wasting
- (2012) D. Clark Files et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Myostatin is a novel tumoral factor that induces cancer cachexia
- (2012) Sudarsanareddy Lokireddy et al. BIOCHEMICAL JOURNAL
- TWEAK and TRAF6 regulate skeletal muscle atrophy
- (2012) Ashok Kumar et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Cellular and molecular mechanisms of muscle atrophy
- (2012) P. Bonaldo et al. Disease Models & Mechanisms
- Nuclear factor-κB signalling and transcriptional regulation in skeletal muscle atrophy
- (2012) Robert W. Jackman et al. EXPERIMENTAL PHYSIOLOGY
- Attenuation of unloading-induced rat soleus atrophy with the heat-shock protein inducer 17-(allylamino)-17-demethoxygeldanamycin
- (2012) Yulia N. Lomonosova et al. FASEB JOURNAL
- Upregulation of proteasome activity in muscle RING finger 1-null mice following denervation
- (2012) Aldrin V. Gomes et al. FASEB JOURNAL
- Histone deacetylase inhibition suppresses myogenin-dependent atrogene activation in spinal muscular atrophy mice
- (2012) Katherine V. Bricceno et al. HUMAN MOLECULAR GENETICS
- MAPK signaling in the quadriceps of patients with chronic obstructive pulmonary disease
- (2012) Bruno B. Lemire et al. JOURNAL OF APPLIED PHYSIOLOGY
- Stress-induced Skeletal Muscle Gadd45a Expression Reprograms Myonuclei and Causes Muscle Atrophy
- (2012) Scott M. Ebert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ubiquitylation by Trim32 causes coupled loss of desmin, Z-bands, and thin filaments in muscle atrophy
- (2012) Shenhav Cohen et al. JOURNAL OF CELL BIOLOGY
- HECT and RING finger families of E3 ubiquitin ligases at a glance
- (2012) M. B. Metzger et al. JOURNAL OF CELL SCIENCE
- Non-canonical ubiquitin-based signals for proteasomal degradation
- (2012) Y. Kravtsova-Ivantsiv et al. JOURNAL OF CELL SCIENCE
- Developmental regulation of MURF E3 ubiquitin ligases in skeletal muscle
- (2012) Sue Perera et al. JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY
- The E3 Ubiquitin Ligase TRAF6 Intercedes in Starvation-Induced Skeletal Muscle Atrophy through Multiple Mechanisms
- (2012) P. K. Paul et al. MOLECULAR AND CELLULAR BIOLOGY
- Diaphragm muscle atrophy in the mouse after long-term mechanical ventilation
- (2012) Huibin Tang et al. MUSCLE & NERVE
- Longitudinal characterization of functional, morphologic, and biochemical adaptations in mouse skeletal muscle with hindlimb suspension
- (2012) Andrea M. Hanson et al. MUSCLE & NERVE
- Foxo/Atrogin induction in human and experimental myositis
- (2012) Han-Kyu Lee et al. NEUROBIOLOGY OF DISEASE
- The ChIP-seq-Defined Networks of Bcl-3 Gene Binding Support Its Required Role in Skeletal Muscle Atrophy
- (2012) Robert W. Jackman et al. PLoS One
- The Ubiquitin Ligase Nedd4-1 Participates in Denervation-Induced Skeletal Muscle Atrophy in Mice
- (2012) Preena Nagpal et al. PLoS One
- p38β MAPK upregulates atrogin1/MAFbx by specific phosphorylation of C/EBPβ
- (2012) Guohua Zhang et al. Skeletal Muscle
- Cardiac proteasome activity in muscle ring finger-1 null mice at rest and following synthetic glucocorticoid treatment
- (2011) Darren T. Hwee et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Clenbuterol suppresses proteasomal and lysosomal proteolysis and atrophy-related genes in denervated rat soleus muscles independently of Akt
- (2011) Dawit A. P. Gonçalves et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Functional interactions between ubiquitin E2 enzymes and TRIM proteins
- (2011) Luisa M. Napolitano et al. BIOCHEMICAL JOURNAL
- The proteasome inhibitor MG132 reduces immobilization-induced skeletal muscle atrophy in mice
- (2011) Annabelle Z Caron et al. BMC MUSCULOSKELETAL DISORDERS
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- (2011) Noriaki Shimizu et al. Cell Metabolism
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- (2011) Guohua Zhang et al. EMBO JOURNAL
- Muscle actin is polyubiquitinylated in vitro and in vivo and targeted for breakdown by the E3 ligase MuRF1
- (2011) Cécile Polge et al. FASEB JOURNAL
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- (2011) Shogo Wada et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Back to your heart: Ubiquitin proteasome system-regulated signal transduction
- (2011) Andrea L. Portbury et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Differential gene expression of muscle-specific ubiquitin ligase MAFbx/Atrogin-1 and MuRF1 in response to immobilization-induced atrophy of slow-twitch and fast-twitch muscles
- (2011) Takeshi Okamoto et al. Journal of Physiological Sciences
- Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: underlying mechanisms
- (2011) Julien Ochala et al. JOURNAL OF PHYSIOLOGY-LONDON
- Muscle sparing in muscle RING finger 1 null mice: response to synthetic glucocorticoids
- (2011) Leslie M. Baehr et al. JOURNAL OF PHYSIOLOGY-LONDON
- Retraction: Myostatin Induces Degradation of Sarcomeric Proteins through a Smad3 Signaling Mechanism During Skeletal Muscle Wasting
- (2011) Sudarsanareddy Lokireddy et al. MOLECULAR ENDOCRINOLOGY
- Transforming growth factor-beta induces skeletal muscle atrophy and fibrosis through the induction of atrogin-1 and scleraxis
- (2011) Christopher L. Mendias et al. MUSCLE & NERVE
- Identification of Genes that Elicit Disuse Muscle Atrophy via the Transcription Factors p50 and Bcl-3
- (2011) Chia-Ling Wu et al. PLoS One
- Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases
- (2010) Viviana Moresi et al. CELL
- Toll-like receptor 4 mediates lipopolysaccharide-induced muscle catabolism via coordinate activation of ubiquitin-proteasome and autophagy-lysosome pathways
- (2010) Alexander Doyle et al. FASEB JOURNAL
- Effects of 3 days unloading on molecular regulators of muscle size in humans
- (2010) T. Gustafsson et al. JOURNAL OF APPLIED PHYSIOLOGY
- Myostatin expression is increased by food deprivation in a muscle-specific manner and contributes to muscle atrophy during prolonged food deprivation in mice
- (2010) David L. Allen et al. JOURNAL OF APPLIED PHYSIOLOGY
- Muscle Wasting in Aged, Sarcopenic Rats Is Associated with Enhanced Activity of the Ubiquitin Proteasome Pathway
- (2010) Mikael Altun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modulation of Muscle Atrophy, Fatigue and MLC Phosphorylation by MuRF1 as Indicated by Hindlimb Suspension Studies on MuRF1-KO Mice
- (2010) Siegfried Labeit et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice
- (2010) Pradyut K. Paul et al. JOURNAL OF CELL BIOLOGY
- The GH/IGF1 axis and signaling pathways in the muscle and bone: mechanisms underlying age-related skeletal muscle wasting and osteoporosis
- (2010) Sebastio Perrini et al. JOURNAL OF ENDOCRINOLOGY
- Heart failure increases atrogin-1 and MuRF1 gene expression in skeletal muscle with fiber type-specific atrophy
- (2010) Robson Francisco Carvalho et al. JOURNAL OF MOLECULAR HISTOLOGY
- p38 MAPK Participates in Muscle-Specific RING Finger 1-Mediated Atrophy in Cast-Immobilized Rat Gastrocnemius Muscle
- (2010) Junghwan Kim et al. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
- Branched-chain amino acids protect against dexamethasone-induced soleus muscle atrophy in rats
- (2010) Daisuke Yamamoto et al. MUSCLE & NERVE
- Leucine attenuates skeletal muscle wasting via inhibition of ubiquitin ligases
- (2010) Igor L. Baptista et al. MUSCLE & NERVE
- Muscle Wasting and Impaired Myogenesis in Tumor Bearing Mice Are Prevented by ERK Inhibition
- (2010) Fabio Penna et al. PLoS One
- Procysteine Stimulates Expression of Key Anabolic Factors and Reduces Plantaris Atrophy in Alcohol-Fed Rats
- (2009) Jeffrey S. Otis et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Smad2 and 3 transcription factors control muscle mass in adulthood
- (2009) Roberta Sartori et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- FOXO signaling is required for disuse muscle atrophy and is directly regulated by Hsp70
- (2009) Sarah M. Senf et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Ghrelin inhibits skeletal muscle protein breakdown in rats with thermal injury through normalizing elevated expression of E3 ubiquitin ligases MuRF1 and MAFbx
- (2009) Ambikaipakan Balasubramaniam et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Cellular Markers of Muscle Atrophy in Chronic Obstructive Pulmonary Disease
- (2009) Pamela J. Plant et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- RING Domain E3 Ubiquitin Ligases
- (2009) Raymond J. Deshaies et al. Annual Review of Biochemistry
- Upregulation of myostatin gene expression in streptozotocin-induced type 1 diabetes mice is attenuated by insulin
- (2009) Yuewen Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Attenuation of proteolysis and muscle wasting by curcumin c3 complex in MAC16 colon tumour-bearing mice
- (2009) Rafat A. Siddiqui et al. BRITISH JOURNAL OF NUTRITION
- Mechanisms Involved in 3′,5′-Cyclic Adenosine Monophosphate-Mediated Inhibition of the Ubiquitin-Proteasome System in Skeletal Muscle
- (2009) Dawit A. P. Gonçalves et al. ENDOCRINOLOGY
- REDD1 Is a Major Target of Testosterone Action in Preventing Dexamethasone-Induced Muscle Loss
- (2009) Yong Wu et al. ENDOCRINOLOGY
- Expression of NF-κB and IκB proteins in skeletal muscle of gastric cancer patients
- (2009) Mary G. Rhoads et al. EUROPEAN JOURNAL OF CANCER
- Atrophy and hypertrophy signalling in the diaphragm of patients with COPD
- (2009) D. Testelmans et al. EUROPEAN RESPIRATORY JOURNAL
- Dynamic interactions of proteins in complex networks: identifying the complete set of interacting E2s for functional investigation of E3-dependent protein ubiquitination
- (2009) Devin E. Christensen et al. FEBS Journal
- Identification of MAFbx as a myogenin-engaged F-box protein in SCF ubiquitin ligase
- (2009) Misako Jogo et al. FEBS LETTERS
- Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component
- (2009) Elena Kudryashova et al. HUMAN MOLECULAR GENETICS
- Evidence for the contribution of insulin resistance to the development of cachexia in tumor-bearing mice
- (2009) Michelle L. Asp et al. INTERNATIONAL JOURNAL OF CANCER
- Time course expression of Foxo transcription factors in skeletal muscle following corticosteroid administration
- (2009) John E. Cho et al. JOURNAL OF APPLIED PHYSIOLOGY
- The 26 S Proteasome: From Basic Mechanisms to Drug Targeting
- (2009) Ami Navon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation
- (2009) Shenhav Cohen et al. JOURNAL OF CELL BIOLOGY
- Atrogin-1, MuRF1, and FoXO, as well as phosphorylated GSK-3β and 4E-BP1 are reduced in skeletal muscle of chronic spinal cord-injured patients
- (2009) Bertrand Léger et al. MUSCLE & NERVE
- Ghrelin receptor agonist, GHRP-2, attenuates burn injury-induced MuRF-1 and MAFbx expression and muscle proteolysis in rats
- (2009) Sulaiman Sheriff et al. PEPTIDES
- Differential skeletal muscle gene expression after upper or lower motor neuron transection
- (2009) Richard J. Zeman et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation
- (2009) W.-L. Yang et al. SCIENCE
- Regulation of Signaling Pathways Downstream of IGF-I/Insulin by Androgen in Skeletal Muscle of Glucocorticoid-Treated Rats
- (2009) Hui-Nan Yin et al. JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE
- TNF induction of atrogin-1/MAFbx mRNA depends on Foxo4 expression but not AKT-Foxo1/3 signaling
- (2008) Jennifer S. Moylan et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Skeletal and cardiac myopathy in HIV-1 transgenic rats
- (2008) Anne M. Pruznak et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene
- (2008) David S. Waddell et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Acute alcohol intoxication increases atrogin-1 and MuRF1 mRNA without increasing proteolysis in skeletal muscle
- (2008) Thomas C. Vary et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Targeting Proteins for Destruction by the Ubiquitin System: Implications for Human Pathobiology
- (2008) Alan L. Schwartz et al. Annual Review of Pharmacology and Toxicology
- Structural Analysis of B-Box 2 from MuRF1: Identification of a Novel Self-Association Pattern in a RING-like Fold†‡
- (2008) Michael Mrosek et al. BIOCHEMISTRY
- Regulation of muscle growth in neonates
- (2008) Teresa A Davis et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- The initiation factor eIF3-f is a major target for Atrogin1/MAFbx function in skeletal muscle atrophy
- (2008) Julie Lagirand-Cantaloube et al. EMBO JOURNAL
- Hsp70 overexpression inhibits NF-κB and Foxo3a transcriptional activities and prevents skeletal muscle atrophy
- (2008) Sarah M. Senf et al. FASEB JOURNAL
- The IκB kinases IKKα and IKKβ are necessary and sufficient for skeletal muscle atrophy
- (2008) Darin Van Gammeren et al. FASEB JOURNAL
- Molecular biomarkers monitoring human skeletal muscle fibres and microvasculature following long-term bed rest with and without countermeasures
- (2008) M. Salanova et al. JOURNAL OF ANATOMY
- Effects of spaceflight on murine skeletal muscle gene expression
- (2008) David L. Allen et al. JOURNAL OF APPLIED PHYSIOLOGY
- Cellular mechanisms regulating protein synthesis and skeletal muscle hypertrophy in animals
- (2008) Mitsunori Miyazaki et al. JOURNAL OF APPLIED PHYSIOLOGY
- MuRF1-dependent Regulation of Systemic Carbohydrate Metabolism as Revealed from Transgenic Mouse Studies
- (2008) Stephanie Hirner et al. JOURNAL OF MOLECULAR BIOLOGY
- Induction of MuRF1 Is Essential for TNF-α-Induced Loss of Muscle Function in Mice
- (2008) Volker Adams et al. JOURNAL OF MOLECULAR BIOLOGY
- Testosterone protects against dexamethasone-induced muscle atrophy, protein degradation and MAFbx upregulation
- (2008) Weidong Zhao et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Rapid Disuse Atrophy of Diaphragm Fibers in Mechanically Ventilated Humans
- (2008) Sanford Levine et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effect of HIV-1-related protein expression on cardiac and skeletal muscles from transgenic rats
- (2008) Jeffrey S Otis et al. AIDS Research and Therapy
- Exercise and immobilization in aging animals: The involvement of oxidative stress and NF-κB activation
- (2007) Marina Bar-Shai et al. FREE RADICAL BIOLOGY AND MEDICINE
- Muscle RING-Finger Protein-1 (MuRF1) as a Connector of Muscle Energy Metabolism and Protein Synthesis
- (2007) Suguru Koyama et al. JOURNAL OF MOLECULAR BIOLOGY
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