The Inflammatory Profile of Obesity and the Role on Pulmonary Bacterial and Viral Infections

Global pandemics interconnected — obesity, impaired metabolic health and COVID-19

(2021) Norbert Stefan et al.   Nature Reviews Endocrinology

The Obesity Paradox in Sepsis: A Theoretical Framework

(2020) Jamie Robinson et al.   Biological Research for Nursing

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

(2020) Waradon Sungnak et al.   NATURE MEDICINE

Morbid Obesity as an Independent Risk Factor for COVID‐19 Mortality in Hospitalized Patients Younger than 50

(2020) Eyal Klang et al.   Obesity

Targeting the Adipose Tissue in COVID‐19

(2020) Alexis Elias Malavazos et al.   Obesity

Cytokine release syndrome in severe COVID-19

(2020) John B. Moore et al.   SCIENCE

Fat-on-a-Chip models for research and discovery in obesity and its metabolic co-morbidities

(2020) Michelle McCarthy et al.   TISSUE ENGINEERING PART B-REVIEWS

WAT-on-a-chip integrating human mature white adipocytes for mechanistic research and pharmaceutical applications

(2020) Julia Rogal et al.   Scientific Reports

Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues

(2020) Meng-Yuan Li et al.   Infectious Diseases of Poverty

Obesity and the Risk of Intubation or Death in Patients With Coronavirus Disease 2019

(2020) Rachel C. Frank et al.   CRITICAL CARE MEDICINE

Computed Tomography Highlights Increased Visceral Adiposity Associated With Critical Illness in COVID-19

(2020) Sofia Battisti et al.   DIABETES CARE

Obesity as a Potential Predictor of Disease Severity in Young COVID‐19 Patients: A Retrospective Study

(2020) Ming Deng et al.   Obesity

The Collision of Meta-Inflammation and SARS-CoV-2 Pandemic Infection

(2020) Gabrielle P Huizinga et al.   ENDOCRINOLOGY

Strengthening resistance to the COVID-19 pandemic and fostering future resilience requires concerted action on obesity

(2020) Angela M. Jackson-Morris et al.   Global Health Action

Modeling Adipogenesis: Current and Future Perspective

(2020) Hisham F. Bahmad et al.   Cells

Covid-19: Fat, Obesity, Inflammation, Ethnicity, and Sex Differences

(2020) Indrikis A. Krams et al.   Pathogens

Generation of immune cell containing adipose organoids for in vitro analysis of immune metabolism

(2020) Jacqueline Taylor et al.   Scientific Reports

Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes

(2019) Matthew J. Harms et al.   Cell Reports

Human adipose stromal-vascular fraction self-organizes to form vascularized adipose tissue in 3D cultures

(2019) Sandra Muller et al.   Scientific Reports

Influenza Virus-Induced Robust Expression of SOCS3 Contributes to Excessive Production of IL-6

(2019) Shasha Liu et al.   Frontiers in Immunology

Comparing the use of differentiated adipose-derived stem cells and mature adipocytes to model adipose tissue in vitro

(2019) Ann-Cathrin Volz et al.   DIFFERENTIATION

Delayed Pulmonary Apoptosis of Diet-Induced Obesity Mice following Escherichia coli Infection through the Mitochondrial Apoptotic Pathway

(2019) Fengyuan Wang et al.   Oxidative Medicine and Cellular Longevity

Adiponectin Limits IFN-γ and IL-17 Producing CD4 T Cells in Obesity by Restraining Cell Intrinsic Glycolysis

(2019) Jayagopi Surendar et al.   Frontiers in Immunology

Obesity

(2018) Kishore M. Gadde et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Sandwiched White Adipose Tissue: A Microphysiological System of Primary Human Adipose Tissue

(2018) Frank H. Lau et al.   TISSUE ENGINEERING PART C-METHODS

Scaffold-free generation of uniform adipose spheroids for metabolism research and drug discovery

(2018) Aloysius J. Klingelhutz et al.   Scientific Reports

Automated microfluidic droplet sampling with integrated, mix-and-read immunoassays to resolve endocrine tissue secretion dynamics

(2018) Xiangpeng Li et al.   LAB ON A CHIP

Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies

(2018) Collin D. Edington et al.   Scientific Reports

Histopathological Changes Caused by Inflammation and Oxidative Stress in Diet-Induced-Obese Mouse following Experimental Lung Injury

(2018) Fengyuan Wang et al.   Scientific Reports

3D collagen microfibers stimulate the functionality of preadipocytes and maintain the phenotype of mature adipocytes for long term cultures

(2018) Fiona Louis et al.   Acta Biomaterialia

Stem-cell based organ-on-a-chip models for diabetes research

(2018) Julia Rogal et al.   ADVANCED DRUG DELIVERY REVIEWS

Comparative Expression of Renin-Angiotensin Pathway Proteins in Visceral Versus Subcutaneous Fat

(2018) Yuebo Zhang et al.   Frontiers in Physiology

Interferon-gamma released from omental adipose tissue of insulin-resistant humans alters adipocyte phenotype and impairs response to insulin and adiponectin release

(2017) J M Wentworth et al.   INTERNATIONAL JOURNAL OF OBESITY

Increased risk of influenza among vaccinated adults who are obese

(2017) S D Neidich et al.   INTERNATIONAL JOURNAL OF OBESITY

B Cell Activity Is Impaired in Human and Mouse Obesity and Is Responsive to an Essential Fatty Acid upon Murine Influenza Infection

(2017) Rasagna Kosaraju et al.   JOURNAL OF IMMUNOLOGY

Variability in responses observed in human white adipose tissue models

(2017) Rosalyn D. Abbott et al.   Journal of Tissue Engineering and Regenerative Medicine

Obesity paradox in patients with community-acquired pneumonia: Is inflammation the missing link?

(2017) Nina Braun et al.   NUTRITION

The Leptin Receptor Complex: Heavier Than Expected?

(2017) Joris Wauman et al.   Frontiers in Endocrinology

Silk as a Biomaterial to Support Long-Term Three-Dimensional Tissue Cultures

(2016) Rosalyn D. Abbott et al.   ACS Applied Materials & Interfaces

A Comparative Study of Lung Host Defense in Murine Obesity Models. Insights into Neutrophil Function

(2016) Niki D. J. Ubags et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Diet-induced obese mice exhibit altered immune responses to acute lung injury induced by Escherichia coli

(2016) Taomei Wan et al.   Obesity

New obesity classification criteria as a tool for bariatric surgery indication

(2016) Antonino De Lorenzo   WORLD JOURNAL OF GASTROENTEROLOGY

The Use of Silk as a Scaffold for Mature, Sustainable Unilocular Adipose 3D Tissue Engineered Systems

(2016) Rosalyn D. Abbott et al.   Advanced Healthcare Materials

A microfluidic interface for the culture and sampling of adiponectin from primary adipocytes

(2015) Leah A. Godwin et al.   ANALYST

Obesity not associated with severity among hospitalized adults with seasonal influenza virus infection

(2015) Elise S. Braun et al.   INFECTION

Methacrylated gelatin and mature adipocytes are promising components for adipose tissue engineering

(2015) Birgit Huber et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Obesity Increases Mortality and Modulates the Lung Metabolome during Pandemic H1N1 Influenza Virus Infection in Mice

(2015) J. Justin Milner et al.   JOURNAL OF IMMUNOLOGY

Adipsin Is an Adipokine that Improves β Cell Function in Diabetes

(2014) James C. Lo et al.   CELL

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

MECHANISMS IN ENDOCRINOLOGY: White, brown and pink adipocytes: the extraordinary plasticity of the adipose organ

(2014) Antonio Giordano et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Impaired Clearance of Influenza A Virus in Obese, Leptin Receptor Deficient Mice Is Independent of Leptin Signaling in the Lung Epithelium and Macrophages

(2014) Kathryn A. Radigan et al.   PLoS One

No Impairment in Host Defense against Streptococcus pneumoniae in Obese CPEfat/fat Mice

(2014) Peter Mancuso et al.   PLoS One

Reconfigurable microfluidic hanging drop network for multi-tissue interaction and analysis

(2014) Olivier Frey et al.   Nature Communications

State of the art paper Biochemistry of adipose tissue: an endocrine organ

(2013) Marisa Coelho et al.   Archives of Medical Science

Leptin: molecular mechanisms, systemic pro-inflammatory effects, and clinical implications

(2013) Gilberto Paz-Filho et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

Plasma SFRP5 levels are decreased in Chinese subjects with obesity and type 2 diabetes and negatively correlated with parameters of insulin resistance

(2013) Zhenping Hu et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

The emerging use of zebrafish to model metabolic disease

(2013) A. Seth et al.   Disease Models & Mechanisms

Systematic Reviews of Animal Models: Methodology versus Epistemology

(2013) Ray Greek et al.   International Journal of Medical Sciences

Leptin Mediates the Pathogenesis of Severe 2009 Pandemic Influenza A(H1N1) Infection Associated With Cytokine Dysregulation in Mice With Diet-Induced Obesity

(2013) Anna J. X. Zhang et al.   JOURNAL OF INFECTIOUS DISEASES

Overweight and obese adult humans have a defective cellular immune response to pandemic H1N1 Influenza a virus

(2013) Heather A. Paich et al.   Obesity

Obesity Paradox in End-Stage Kidney Disease Patients

(2013) Jongha Park et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Parabiosis in Mice: A Detailed Protocol

(2013) Paniz Kamran et al.   Jove-Journal of Visualized Experiments

Laboratory animals as surrogate models of human obesity

(2012) Cecilia Nilsson et al.   ACTA PHARMACOLOGICA SINICA

Obesity is associated with improved survival in community-acquired pneumonia

(2012) Anika Singanayagam et al.   EUROPEAN RESPIRATORY JOURNAL

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Adipose tissue mass and location affect circulating adiponectin levels

(2011) A. T. Turer et al.   DIABETOLOGIA

Leptin receptor signaling: pathways to leptin resistance

(2011) Joris Wauman   Frontiers in Bioscience-Landmark

Obese mice have increased morbidity and mortality compared to non-obese mice during infection with the 2009 pandemic H1N1 influenza virus

(2011) Judith D. Easterbrook et al.   Influenza and Other Respiratory Viruses

Adipose tissue remodeling and obesity

(2011) Kai Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

Diet-Induced Obesity Dramatically Reduces the Efficacy of a 2009 Pandemic H1N1 Vaccine in a Mouse Model

(2011) Yong-Hoon Kim et al.   JOURNAL OF INFECTIOUS DISEASES

Excess Visceral Adipose Tissue/Ectopic Fat

(2011) Jean-Pierre Després   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Obesity is associated with higher risk of intensive care unit admission and death in influenza A (H1N1) patients: a systematic review and meta-analysis

(2011) L. Fezeu et al.   Obesity Reviews

Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome — An allostatic perspective

(2010) Sam Virtue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The obesity paradox in community-acquired bacterial pneumonia

(2010) Vicente F. Corrales-Medina et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Adiponectin-induced ERK and Akt Phosphorylation Protects against Pancreatic Beta Cell Apoptosis and Increases Insulin Gene Expression and Secretion

(2010) Nadeeja Wijesekara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diet-Induced Obesity Impairs the T Cell Memory Response to Influenza Virus Infection

(2010) E. A. Karlsson et al.   JOURNAL OF IMMUNOLOGY

A historical perspective on leptin

(2010) Douglas L Coleman   NATURE MEDICINE

Morbid Obesity as a Risk Factor for Hospitalization and Death Due to 2009 Pandemic Influenza A(H1N1) Disease

(2010) Oliver W. Morgan et al.   PLoS One

Sfrp5 Is an Anti-Inflammatory Adipokine That Modulates Metabolic Dysfunction in Obesity

(2010) N. Ouchi et al.   SCIENCE

Obesity and leptin resistance: distinguishing cause from effect

(2010) Martin G. Myers et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The 2009 A (H1N1) influenza virus pandemic: A review

(2010) Marc P. Girard et al.   VACCINE

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

IL-18 overexpression promotes vascular inflammation and remodeling in a rat model of metabolic syndrome

(2009) Hong-wei Tan et al.   ATHEROSCLEROSIS

Angiopoietin-like Protein 2 Promotes Chronic Adipose Tissue Inflammation and Obesity-Related Systemic Insulin Resistance

(2009) Mitsuhisa Tabata et al.   Cell Metabolism

CXC Ligand 5 Is an Adipose-Tissue Derived Factor that Links Obesity to Insulin Resistance

(2009) Carine Chavey et al.   Cell Metabolism

Adiponectin Promotes Macrophage Polarization toward an Anti-inflammatory Phenotype

(2009) Koji Ohashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obesity, inflammation, and atherosclerosis

(2009) Viviane Z. Rocha et al.   Nature Reviews Cardiology

Hospitalized Patients with 2009 H1N1 Influenza in the United States, April–June 2009

(2009) Seema Jain et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interferon and cytokine responses to SARS-coronavirus infection

(2008) Volker Thiel et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Selective impairment in dendritic cell function and altered antigen-specific CD8+T-cell responses in diet-induced obese mice infected with influenza virus

(2008) Alexia G. Smith et al.   IMMUNOLOGY

Influenza A Virus Inhibits Type I IFN Signaling via NF-κB-Dependent Induction of SOCS-3 Expression

(2008) Eva-K. Pauli et al.   PLoS Pathogens

Mechanisms of Leptin Action and Leptin Resistance

(2007) Martin G. Myers et al.   Annual Review of Physiology

The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance

(2007) Gijs H. Goossens   PHYSIOLOGY & BEHAVIOR