Anti-inflammatory effects of Platycodin D on dextran sulfate sodium (DSS) induced colitis and E. coli Lipopolysaccharide (LPS) induced inflammation

Macrophage M1/M2 polarization

(2020) Chen Yunna et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cacalol Acetate, a Sesquiterpene from Psacalium decompositum, Exerts an Anti-inflammatory Effect through LPS/NF-KB Signaling in Raw 264.7 Macrophages

(2020) B. Mora-Ramiro et al.   JOURNAL OF NATURAL PRODUCTS

Epidemiology and Pathogenesis of Ulcerative Colitis

(2020) Lillian Du et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Macrophage polarization in intestinal inflammation and gut homeostasis

(2020) Tamara Cristina Moreira Lopes et al.   INFLAMMATION RESEARCH

At the Forefront of the Mucosal Barrier: The Role of Macrophages in the Intestine

(2020) Barbara Ruder et al.   Cells

Suppression of lipopolysaccharide-induced activation of RAW 264.7 macrophages by Se-methylseleno-l-cysteine

(2020) Guang Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mesenchymal stromal cell-derived exosomes attenuate myocardial ischaemia-reperfusion injury through miR-182-regulated macrophage polarization

(2019) Jinxuan Zhao et al.   CARDIOVASCULAR RESEARCH

Platycodin D triggers the extracellular release of programed death Ligand-1 in lung cancer cells

(2019) Mu-Yang Huang et al.   FOOD AND CHEMICAL TOXICOLOGY

M1 and M2 macrophage polarization and potentially therapeutic naturally occurring compounds

(2019) Youhan Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The role of macrophages in the resolution of inflammation

(2019) Satoshi Watanabe et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD

(2019) Yi Rang Na et al.   Nature Reviews Gastroenterology & Hepatology

Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages

(2019) Marco Orecchioni et al.   Frontiers in Immunology

Post-transcriptional regulation of inflammation by RNA-binding proteins via cis-elements of mRNAs

(2019) Yutaro Uchida et al.   JOURNAL OF BIOCHEMISTRY

Macrophage Rewiring by Nutrient Associated PI3K Dependent Pathways

(2019) Omar Sharif et al.   Frontiers in Immunology

MSC-secreted TGF-β regulates lipopolysaccharide-stimulated macrophage M2-like polarization via the Akt/FoxO1 pathway

(2019) Feng Liu et al.   Stem Cell Research & Therapy

The immunomodulatory role of irisin on osteogenesis via AMPK-mediated macrophage polarization

(2019) Wenbin Ye et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Translating Immunology into Therapeutic Concepts for Inflammatory Bowel Disease

(2018) Holm H. Uhlig et al.   Annual Review of Immunology

Post-transcriptional regulation of immune responses by RNA binding proteins

(2018) Takashi MINO et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Smiglaside A ameliorates LPS-induced acute lung injury by modulating macrophage polarization via AMPK-PPARγ pathway

(2018) Yurong Wang et al.   BIOCHEMICAL PHARMACOLOGY

Cathelicidin-WA attenuates LPS-induced inflammation and redox imbalance through activation of AMPK signaling

(2018) Weiche Wu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Platycodin D, a novel activator of AMP-activated protein kinase, attenuates obesity in db/db mice via regulation of adipogenesis and thermogenesis

(2018) Hye-Lin Kim et al.   PHYTOMEDICINE

Effects of Platycodin D on S100A8/A9-induced inflammatory response in murine mammary carcinoma 4T1 cells

(2018) Yiyi Ye et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Platycodin D protects against cigarette smoke-induced lung inflammation in mice

(2017) Wei Gao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization

(2017) Eleni Vergadi et al.   JOURNAL OF IMMUNOLOGY

Dextran sodium sulfate colitis murine model: An indispensable tool for advancing our understanding of inflammatory bowel diseases pathogenesis

(2017) Derrick D Eichele et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Genetics and Pathogenesis of Inflammatory Bowel Disease

(2016) Ta-Chiang Liu et al.   Annual Review of Pathology-Mechanisms of Disease

The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis

(2016) Ido Amit et al.   NATURE IMMUNOLOGY

Monocyte and Macrophage Plasticity in Tissue Repair and Regeneration

(2015) Amitava Das et al.   AMERICAN JOURNAL OF PATHOLOGY

Macrophage polarization in pathology

(2015) Antonio Sica et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Platycodin D Attenuates Airway Inflammation in a Mouse Model of Allergic Asthma by Regulation NF-κB Pathway

(2015) Tianzhu Zhang et al.   INFLAMMATION

Control of macrophage metabolism and activation by mTOR and Akt signaling

(2015) Anthony J. Covarrubias et al.   SEMINARS IN IMMUNOLOGY

Chemerin aggravates DSS-induced colitis by suppressing M2 macrophage polarization

(2014) Yuli Lin et al.   Cellular & Molecular Immunology

Adenosine 5'-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype

(2014) D. Sag et al.   JOURNAL OF IMMUNOLOGY

Transcriptional Control of Macrophage Polarization

(2013) Derin Tugal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Metabolism of inflammation limited by AMPK and pseudo-starvation

(2013) Luke A. J. O'Neill et al.   NATURE

NF-κB in immunobiology

(2011) Matthew S Hayden et al.   CELL RESEARCH

The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells

(2011) Yasutaka Motomura et al.   NATURE IMMUNOLOGY

AMPK agonist downregulates innate and adaptive immune responses in TNBS-induced murine acute and relapsing colitis

(2010) Aiping Bai et al.   BIOCHEMICAL PHARMACOLOGY

The Kinase Akt1 Controls Macrophage Response to Lipopolysaccharide by Regulating MicroRNAs

(2009) Ariadne Androulidaki et al.   IMMUNITY

Anti-inflammatory Activity of Prosapogenin Methyl Ester of Platycodin D via Nuclear Factor-kappaB Pathway Inhibition

(2008) Ji Won Chung et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN