Plasma S1P (Sphingosine-1-Phosphate) Links to Hypertension and Biomarkers of Inflammation and Cardiovascular Disease: Findings From a Translational Investigation

U-shaped association between plasma sphingosine-1-phosphate levels and mortality in patients with chronic systolic heart failure: a prospective cohort study

(2020) Yanbo Xue et al.   Lipids in Health and Disease

Plasma sphingosine 1-phosphate concentrations and cardiovascular autonomic neuropathy in individuals with type 2 diabetes

(2020) Min Young Chung et al.   Scientific Reports

The Malmö Offspring Study (MOS): design, methods and first results

(2020) Louise Brunkwall et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Role of Coronary Artery Calcium for Stratifying Cardiovascular Risk in Adults With Hypertension

(2019) S. M. Iftekhar Uddin et al.   HYPERTENSION

Incorporation of Biomarkers Into Risk Assessment for Allocation of Antihypertensive Medication According to the 2017 ACC/AHA High Blood Pressure Guideline

(2019) Ambarish Pandey et al.   CIRCULATION

Correlation Coefficients

(2018) Patrick Schober et al.   ANESTHESIA AND ANALGESIA

The emerging alliance of sphingosine-1-phosphate signalling and immune cells: from basic mechanisms to implications in hypertension

(2018) Nicholas Don-Doncow et al.   BRITISH JOURNAL OF PHARMACOLOGY

Conceptual Framework for Addressing Residual Atherosclerotic Cardiovascular Disease Risk in the Era of Precision Medicine

(2018) Kershaw V. Patel et al.   CIRCULATION

The Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis in Intestinal Epithelial Cells Regulates Intestinal Barrier Function During Intestinal Epithelial Cells–CD4+T-Cell Interactions

(2018) Tanzhou Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

S1PR1 (Sphingosine-1-Phosphate Receptor 1) Signaling Regulates Blood Flow and PressureNovelty and Significance

(2017) Anna Cantalupo et al.   HYPERTENSION

Global Burden of Hypertension and Systolic Blood Pressure of at Least 110 to 115 mm Hg, 1990-2015

(2017) Mohammad H. Forouzanfar et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Optimization of ultra-high pressure liquid chromatography – tandem mass spectrometry determination in plasma and red blood cells of four sphingolipids and their evaluation as biomarker candidates of Gaucher’s disease

(2017) Caroline Chipeaux et al.   JOURNAL OF CHROMATOGRAPHY A

Plasma sphingosine-1-phosphate concentrations are associated with systolic heart failure in patients with ischemic heart disease

(2017) Amin Polzin et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

An engineered S1P chaperone attenuates hypertension and ischemic injury

(2017) Steven L. Swendeman et al.   Science Signaling

An engineered S1P chaperone attenuates hypertension and ischemic injury

(2017) Steven L. Swendeman et al.   Science Signaling

Association Between Interleukin-18 Level and Left Ventricular Mass Index in Hypertensive Patients

(2017) Süleyman ÖZzbïçer et al.   Korean Circulation Journal

Potential US Population Impact of the 2017 ACC/AHA High Blood Pressure Guideline

(2017) Paul Muntner et al.   CIRCULATION

S1P1 deletion differentially affects TH17 and Regulatory T cells

(2017) Ahmet Eken et al.   Scientific Reports

Endothelial functions of platelet/endothelial cell adhesion molecule-1 (CD31)

(2016) Panida Lertkiatmongkol et al.   CURRENT OPINION IN HEMATOLOGY

Sphingosine-1-Phosphate is Involved in the Occlusive Arteriopathy of Pulmonary Arterial Hypertension

(2016) Salina Gairhe et al.   Pulmonary Circulation

Quantification of sphingosine 1-phosphate by validated LC-MS/MS method revealing strong correlation with apolipoprotein M in plasma but not in serum due to platelet activation during blood coagulation

(2015) Cecilia Frej et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure

(2015) Anna Cantalupo et al.   NATURE MEDICINE

A Randomized Trial of Intensive versus Standard Blood-Pressure Control

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction

(2015) Christoph Tabeling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutically Targeting Tumor Necrosis Factor-α/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage

(2015) Kenji Yagi et al.   STROKE

A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung

(2015) Yidan D. Zhao et al.   PLoS One

Usefulness of serum interleukin-18 in predicting cardiovascular mortality in patients with chronic kidney disease – systems and clinical approach

(2015) Dorota Formanowicz et al.   Scientific Reports

The Sphingosine Kinase 1/Sphingosine-1-Phosphate Pathway in Pulmonary Arterial Hypertension

(2014) Jiwang Chen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The role of sphingosine-1-phosphate in endothelial barrier function

(2014) Brent A. Wilkerson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Higher level of plasma bioactive molecule sphingosine 1-phosphate in women is associated with estrogen

(2014) Shoudong Guo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

HDL-Bound Sphingosine 1-Phosphate (S1P) Predicts the Severity of Coronary Artery Atherosclerosis

(2014) Katherine Sattler et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Sex Differences in T Cells in Hypertension

(2014) Ashlee J. Tipton et al.   CLINICAL THERAPEUTICS

Female Spontaneously Hypertensive Rats Have a Compensatory Increase in Renal Regulatory T Cells in Response to Elevations in Blood Pressure

(2014) Ashlee J. Tipton et al.   HYPERTENSION

Sex and gender differences in control of blood pressure: Figure 1

(2013) Rodrigo Maranon et al.   CLINICAL SCIENCE

Involvement of sphingosine 1-phosphate in palmitate-induced insulin resistance of hepatocytes via the S1P2 receptor subtype

(2013) Susann Fayyaz et al.   DIABETOLOGIA

Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation

(2013) Christopher S Garris et al.   NATURE IMMUNOLOGY

Proximal Cerebral Arteries Develop Myogenic Responsiveness in Heart Failure via Tumor Necrosis Factor-α–Dependent Activation of Sphingosine-1-Phosphate Signaling

(2012) Jingli Yang et al.   CIRCULATION

Hypertension Is Associated with Marked Alterations in Sphingolipid Biology: A Potential Role for Ceramide

(2011) Léon J. A. Spijkers et al.   PLoS One

Sphingosine-1-Phosphate–Dependent Activation of p38 MAPK Maintains Elevated Peripheral Resistance in Heart Failure Through Increased Myogenic Vasoconstriction

(2010) Judith Hoefer et al.   CIRCULATION RESEARCH

Circulating sphingolipid biomarkers in models of type 1 diabetes

(2010) Todd E. Fox et al.   JOURNAL OF LIPID RESEARCH

PECAM-1: Conflicts of interest in inflammation

(2010) Jamie R. Privratsky et al.   LIFE SCIENCES

Sphingosine 1-phosphate induces platelet/endothelial cell adhesion molecule-1 phosphorylation in human endothelial cells through cSrc and Fyn

(2008) Yu-Ting Huang et al.   CELLULAR SIGNALLING

Interleukin-18 Is a Strong Predictor of Cardiovascular Events in Elderly Men With the Metabolic Syndrome: Synergistic effect of inflammation and hyperglycemia

(2008) M. Troseid et al.   DIABETES CARE

Fast unfolding of communities in large networks

(2008) Vincent D Blondel et al.   JOURNAL OF STATISTICAL MECHANICS-THEORY AND EXPERIMENT

Plasma sphingosine-1-phosphate measurement in healthy subjects: close correlation with red blood cell parameters

(2008) R. Ohkawa et al.   ANNALS OF CLINICAL BIOCHEMISTRY