The Sphingosine Kinase 1/Sphingosine-1-Phosphate Pathway in Pulmonary Arterial Hypertension

Sphingosine kinase 1 overexpression stimulates intestinal epithelial cell proliferation through increased c-Myc translation

(2013) Ping Jiang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

ADCYAP1R1and Asthma in Puerto Rican Children

(2013) Wei Chen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis

(2013) Long Shuang Huang et al.   FASEB JOURNAL

Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis

(2012) M. Nagahashi et al.   CANCER RESEARCH

Inhibition of sphingosine kinase 1 suppresses proliferation of glioma cells under hypoxia by attenuating activity of extracellular signal-regulated kinase

(2012) H. Zhang et al.   CELL PROLIFERATION

Sphingosine-1-Phosphate Enhances Satellite Cell Activation in Dystrophic Muscles through a S1PR2/STAT3 Signaling Pathway

(2012) Kenneth C. Loh et al.   PLoS One

Mouse SPNS2 Functions as a Sphingosine-1-Phosphate Transporter in Vascular Endothelial Cells

(2012) Yu Hisano et al.   PLoS One

S1P activates store-operated calcium entry via receptor- and non-receptor-mediated pathways in vascular smooth muscle cells

(2011) Kristen Park Hopson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Sphingosine 1-phosphate stimulates proliferation and migration of satellite cells

(2011) Serena Calise et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Pharmacological relevance and potential of sphingosine 1-phosphate in the vascular system

(2011) Mirjam Schuchardt et al.   BRITISH JOURNAL OF PHARMACOLOGY

Signal Transducers and Activators of Transcription-3/Pim1 Axis Plays a Critical Role in the Pathogenesis of Human Pulmonary Arterial Hypertension

(2011) Roxane Paulin et al.   CIRCULATION

Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease

(2011) Wanli Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Intracellular S1P Generation Is Essential for S1P-Induced Motility of Human Lung Endothelial Cells: Role of Sphingosine Kinase 1 and S1P Lyase

(2011) Evgeny V. Berdyshev et al.   PLoS One

S1P4 Receptor Mediates S1P-Induced Vasoconstriction in Normotensive and Hypertensive Rat Lungs

(2011) Hiroki Ota et al.   Pulmonary Circulation

S1P2 receptor-dependent Rho-kinase activation mediates vasoconstriction in the murine pulmonary circulation induced by sphingosine 1-phosphate

(2010) William S. Szczepaniak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Protection of LPS-Induced Murine Acute Lung Injury by Sphingosine-1-Phosphate Lyase Suppression

(2010) Yutong Zhao et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A Novel Function of Sphingosine Kinase 1 Suppression of JNK Activity in Preventing Inflammation and Injury

(2010) Anke Di et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingosine-1-Phosphate Receptor-2 Regulates Expression of Smooth Muscle Alpha-Actin After Arterial Injury

(2009) Allison D. Grabski et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Sprouty4deficiency potentiates Ras-independent angiogenic signals and tumor growth

(2009) Koji Taniguchi et al.   CANCER SCIENCE

Sphingosine Kinase 1 Is Associated with Gastric Cancer Progression and Poor Survival of Patients

(2009) W. Li et al.   CLINICAL CANCER RESEARCH

High levels of hyaluronan in idiopathic pulmonary arterial hypertension

(2008) Metin Aytekin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Sphingosine 1-Phosphate Potentiates Human Lung Fibroblast Chemotaxis through the S1P2Receptor

(2008) Mitsu Hashimoto et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Sphingosine-1-Phosphate Receptor Subtypes Differentially Regulate Smooth Muscle Cell Phenotype

(2008) Brian R. Wamhoff et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Sphingosine kinase-1 is a hypoxia-regulated gene that stimulates migration of human endothelial cells

(2008) Stephanie Schwalm et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sphingosine Kinase 1: A New Modulator of Hypoxia Inducible Factor 1  during Hypoxia in Human Cancer Cells

(2008) I. Ader et al.   CANCER RESEARCH

G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase

(2008) Shin-ichiro Takashima et al.   CARDIOVASCULAR RESEARCH

Interleukin-1 Regulates the Expression of Sphingosine Kinase 1 in Glioblastoma Cells

(2008) Barbara S. Paugh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

bFGF induces S1P1receptor expression and functionality in human pulmonary artery smooth muscle cells

(2008) Magdalena Birker-Robaczewska et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

"Inside-Out" Signaling of Sphingosine-1-Phosphate: Therapeutic Targets

(2008) K. Takabe et al.   PHARMACOLOGICAL REVIEWS

Sphingosine-1-Phosphate Mediates Transcriptional Regulation of Key Targets Associated with Survival, Proliferation, and Pluripotency in Human Embryonic Stem Cells

(2008) Katie Avery et al.   STEM CELLS AND DEVELOPMENT

Dual and distinct roles for sphingosine kinase 1 and sphingosine 1 phosphate in the response to inflammatory stimuli in RAW macrophages

(2007) Samar M. Hammad et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS