Biophysical characteristics of proteins and living cells exposed to the green tea polyphenol epigallocatechin-3-gallate (EGCg): review of recent advances from molecular mechanisms to nanomedicine and clinical trials

Phytochemicals as Innovative Therapeutic Tools against Cancer Stem Cells

(2015) Emanuele-Salvatore Scarpa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Incubator proof miniaturized Holomonitor toin situmonitor cancer cells exposed to green tea polyphenol and preosteoblast cells adhering on nanostructured titanate surfaces: validity of the measured parameters and their corrections

(2015) Beatrix Peter et al.   JOURNAL OF BIOMEDICAL OPTICS

EGCG synergizes the therapeutic effect of cisplatin and oxaliplatin through autophagic pathway in human colorectal cancer cells

(2015) Fen Hu et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Enhanced uptake and transport of (+)-catechin and (-)-epigallocatechin gallate in niosomal formulation by human intestinal Caco-2 cells

(2014) Qinxin Song et al.   International Journal of Nanomedicine

Synergistic enhancement of anticancer effects on numerous human cancer cell lines treated with the combination of EGCG, other green tea catechins, and anticancer compounds

(2014) Hirota Fujiki et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Differential prooxidative effects of the green tea polyphenol, (-)-epigallocatechin-3-gallate, in normal and oral cancer cells are related to differences in sirtuin 3 signaling

(2014) Ling Tao et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Augmented cellular uptake of nanoparticles using tea catechins: effect of surface modification on nanoparticle–cell interaction

(2014) Yi-Ching Lu et al.   Nanoscale

Self-assembled micellar nanocomplexes comprising green tea catechin derivatives and protein drugs for cancer therapy

(2014) Joo Eun Chung et al.   Nature Nanotechnology

Aortic-Valve Stenosis — From Patients at Risk to Severe Valve Obstruction

(2014) Catherine M. Otto et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reorganisation of the Salivary Mucin Network by Dietary Components: Insights from Green Tea Polyphenols

(2014) Heather S. Davies et al.   PLoS One

Tea Derived Galloylated Polyphenols Cross-Link Purified Gastrointestinal Mucins

(2014) Pantelis Georgiades et al.   PLoS One

Label-free cell phenotypic profiling identifies pharmacologically active compounds in two traditional Chinese medicinal plants

(2014) Xiuli Zhang et al.   RSC Advances

Dependence of cancer cell adhesion kinetics on integrin ligand surface density measured by a high-throughput label-free resonant waveguide grating biosensor

(2014) Norbert Orgovan et al.   Scientific Reports

Optimization on condition of epigallocatechin-3-gallate (EGCG) nanoliposomes by response surface methodology and cellular uptake studies in Caco-2 cells

(2014) Xiaobo Luo et al.   Nanoscale Research Letters

New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate

(2014) Hae-Suk Kim et al.   Redox Biology

Molecular and thermodynamic basis for EGCG-Keratin interaction-part II: Experimental investigation

(2013) Yanyan Zhao et al.   AICHE JOURNAL

Effect of Tea Polyphenols on the Adhesion of Highly Metastatic Human Lung Carcinoma Cell Lines to Endothelial Cells in Vitro

(2013) Feng-Jin Zheng et al.   Asian Pacific Journal of Cancer Prevention

Mechanism-based inhibition of cancer metastasis with (−)-epigallocatechin gallate

(2013) Atsushi Takahashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Binding interaction between (−)-epigallocatechin gallate causes impaired spreading of cancer cells on fibrinogen

(2013) Yasuo SUZUKI et al.   BIOMEDICAL RESEARCH-TOKYO

Antioxidant Enzymes Mediate Survival of Breast Cancer Cells Deprived of Extracellular Matrix

(2013) C. A. Davison et al.   CANCER RESEARCH

Antiproliferative activity of tea catechins associated with casein micelles, using HT29 colon cancer cells

(2013) S. Haratifar et al.   JOURNAL OF DAIRY SCIENCE

Anticancer activities of (−)-epigallocatechin-3-gallate encapsulated nanoliposomes in MCF7 breast cancer cells

(2013) Rita Castillo Cohen de Pace et al.   JOURNAL OF LIPOSOME RESEARCH

Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals

(2013) Shu Wang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Laminin Receptor 37/67LR Regulates Adhesion and Proliferation of Normal Human Intestinal Epithelial Cells

(2013) Taoufik Khalfaoui et al.   PLoS One

Antioxidant Induces DNA Damage, Cell Death and Mutagenicity in Human Lung and Skin Normal Cells

(2013) Linda Y. Lu et al.   Scientific Reports

Nanochemoprevention by encapsulation of (−)-epigallocatechin-3-gallate with bioactive peptides/chitosan nanoparticles for enhancement of its bioavailability

(2012) Bing Hu et al.   CHEMICAL COMMUNICATIONS

Novel epigallocatechin gallate analogs as potential anticancer agents: a patent review (2009 – present)

(2012) Kristin Landis-Piwowar et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Epigallocatechin-3-gallate and penta-O-galloyl-β-d-glucose inhibit protein phosphatase-1

(2012) Andrea Kiss et al.   FEBS Journal

Interaction of Tea Polyphenols and Food Constituents with Model Gut Epithelia: The Protective Role of the Mucus Gel Layer

(2012) Eleanor M. D’Agostino et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Core–shell mesoporous silica nanoparticles improve HeLa cell growth and proliferation inhibition by (−)-epigallocatechin-3-gallate by prolonging the half-life

(2012) Jie Ding et al.   JOURNAL OF MATERIALS CHEMISTRY

Experimental and Theoretical Studies on the Binding of Epigallocatechin Gallate to Purified Porcine Gastric Mucin

(2012) Yanyan Zhao et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Green Tea Polyphenol EGCG Sensing Motif on the 67-kDa Laminin Receptor

(2012) Yoshinori Fujimura et al.   PLoS One

Laminin receptor specific therapeutic gold nanoparticles (198AuNP-EGCg) show efficacy in treating prostate cancer

(2012) R. Shukla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages

(2011) Wei Li et al.   BIOCHEMICAL PHARMACOLOGY

Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications

(2011) Brahma N. Singh et al.   BIOCHEMICAL PHARMACOLOGY

Human Serum Albumin as an Antioxidant in the Oxidation of (−)-Epigallocatechin Gallate: Participation of Reversible Covalent Binding for Interaction and Stabilization

(2011) Takeshi ISHII et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Green tea polyphenol epigallocatechin-3-gallate inhibits TLR2 signaling induced by peptidoglycan through the polyphenol sensing molecule 67-kDa laminin receptor

(2011) Eui-Hong Byun et al.   FEBS LETTERS

Epigallocatechin-3-gallate (EGCG) for Clinical Trials: More Pitfalls than Promises?

(2011) Derliz Mereles et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Vitamin E and the Risk of Prostate Cancer

(2011) Eric A. Klein et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Early transcriptional pattern of angiogenesis induced by EGCG treatment in cervical tumour cells

(2011) Oana Tudoran et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Broad inhibition of plasmodium falciparum cytoadherence by (+)-epigallocatechin gallate

(2011) Pradeep R Patil et al.   MALARIA JOURNAL

Green tea polyphenol sensing

(2011) Hirofumi TACHIBANA   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Epigallocatechin-3-gallate suppresses the expression of HSP70 and HSP90 and exhibits anti-tumor activity in vitro and in vivo

(2010) Phan LCHB Tran et al.   BMC CANCER

Chitosan nanoparticles enhance the intestinal absorption of the green tea catechins (+)-catechin and (−)-epigallocatechin gallate

(2010) Admire Dube et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Green tea polyphenol EGCG blunts androgen receptor function in prostate cancer

(2010) Imtiaz A. Siddiqui et al.   FASEB JOURNAL

Synergistic and Additive Effects of Epigallocatechin Gallate and Digitonin on Plasmodium Sporozoite Survival and Motility

(2010) Janina K. Hellmann et al.   PLoS One

Limitations of MTT and MTS-Based Assays for Measurement of Antiproliferative Activity of Green Tea Polyphenols

(2010) Piwen Wang et al.   PLoS One

Epigallocatechin gallate reduces human monocyte mobility and adhesion in vitro

(2009) Esther Melgarejo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Polyphenol Control of Cell Spreading on Glycoprotein Substrata

(2009) James McColl et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

(−)-Epigallocatechin-3-Gallate (EGCG) Maintains κ-Casein in Its Pre-Fibrillar State without Redirecting Its Aggregation Pathway

(2009) Sean A. Hudson et al.   JOURNAL OF MOLECULAR BIOLOGY

The impact of the 67kDa laminin receptor on both cell-surface binding and anti-allergic action of tea catechins

(2008) Yoshinori Fujimura et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Involvement of 67-kDa laminin receptor-mediated myosin phosphatase activation in antiproliferative effect of epigallocatechin-3-O-gallate at a physiological concentration on Caco-2 colon cancer cells

(2008) Daisuke Umeda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

EGCG inhibits mammary cancer cell migration through inhibition of nitric oxide synthase and guanylate cyclase

(2008) Thejass Punathil et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The 67 kDa laminin receptor: structure, function and role in disease

(2008) John Nelson et al.   BIOSCIENCE REPORTS

Simultaneous Manipulation of Multiple Brain Targets by Green Tea Catechins: A Potential Neuroprotective Strategy for Alzheimer and Parkinson Diseases

(2008) Silvia A. Mandel et al.   CNS Neuroscience & Therapeutics

Structural hysteresis and hierarchy in adsorbed glycoproteins

(2008) Robert Horvath et al.   JOURNAL OF CHEMICAL PHYSICS

Combined effect of epigallocatechin gallate and triclosan on enoyl-ACP reductase of Mycobacterium tuberculosis

(2007) Shailendra Kumar Sharma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS