hERG1 potassium channel in cancer cells: a tool to reprogram immortality
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Title
hERG1 potassium channel in cancer cells: a tool to reprogram immortality
Authors
Keywords
hERG1, Cancer, Therapy, Activator, Blocker
Journal
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
Volume 45, Issue 7, Pages 649-655
Publisher
Springer Nature
Online
2016-09-20
DOI
10.1007/s00249-016-1169-3
References
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Note: Only part of the references are listed.- Stimulation of hERG1 channel activity promotes a calcium-dependent degradation of cyclin E2, but not cyclin E1, in breast cancer cells
- (2015) Mathew Perez-Neut et al. Oncotarget
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- (2015) Mathew Perez-Neut et al. Oncotarget
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- (2014) Ingo Staudacher et al. PLoS One
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- (2013) Joseph J Babcock et al. ACTA PHARMACOLOGICA SINICA
- Role of autophagy in cancer prevention, development and therapy
- (2013) G. Vignir Helgason et al. Essays in Biochemistry
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- (2013) Mine S. Cicek et al. HUMAN MOLECULAR GENETICS
- Mutational landscape and significance across 12 major cancer types
- (2013) Cyriac Kandoth et al. NATURE
- Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes
- (2013) Kimberly R. Doherty et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Potassium channel activation inhibits proliferation of breast cancer cells by activating a senescence program
- (2013) K Lansu et al. Cell Death & Disease
- Arsenic trioxide-induced hERG K+ channel deficiency can be rescued by matrine and oxymatrine through up-regulating transcription factor Sp1 expression
- (2012) Ying Zhang et al. BIOCHEMICAL PHARMACOLOGY
- Blocking of the Human Ether-^|^agrave;-go-go-Related Gene Channel by Imatinib Mesylate
- (2012) Qian Dong et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- hERG K+ Channels: Structure, Function, and Clinical Significance
- (2012) Jamie I. Vandenberg et al. PHYSIOLOGICAL REVIEWS
- Role of Autophagy in Cancer Prevention
- (2011) Hsin-Yi Chen et al. Cancer Prevention Research
- Four faces of cellular senescence
- (2011) Francis Rodier et al. JOURNAL OF CELL BIOLOGY
- Imatinib has the potential to exert its antileukemia effects by down-regulating hERG1 K+ channels in chronic myelogenous leukemia
- (2011) Fang Zheng et al. MEDICAL ONCOLOGY
- Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells
- (2011) Günter Glassmeier et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2+breast cancer patients
- (2011) Maurizio Scaltriti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of the voltage-insensitive step of HERG activation by extracellular pH
- (2010) Qinlian Zhou et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Electrophysiological Effects of the Anti-Cancer Drug Lapatinib on Cardiac Repolarization
- (2010) Hyang-Ae Lee et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Pharmacological Activation of Kv11.1 in Transgenic Long QT-1 Rabbits
- (2010) Bo Hjorth Bentzen et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Assessing proarrhythmic potential of drugs when optimal studies are infeasible
- (2009) Edwin P. Rock et al. AMERICAN HEART JOURNAL
- Dexrazoxane protects the heart from acute doxorubicin-induced QT prolongation: a key role for IKs
- (2009) J Ducroq et al. BRITISH JOURNAL OF PHARMACOLOGY
- Update on the evaluation of a new drug for effects on cardiac repolarization in humans: issues in early drug development
- (2009) Vaibhav Salvi et al. BRITISH JOURNAL OF PHARMACOLOGY
- Expression and significance of HERG (KCNH2) potassium channels in the regulation of MDA-MB-435S melanoma cell proliferation and migration
- (2009) Emad Afrasiabi et al. CELLULAR SIGNALLING
- Characterization of Erg K+Channels in α- and β-Cells of Mouse and Human Islets
- (2009) Alexandre B. Hardy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ether-à-go-go-related gene K+channels contribute to threshold excitability of mouse auditory brainstem neurons
- (2009) Rachael M. Hardman et al. JOURNAL OF PHYSIOLOGY-LONDON
- Voltage-gated potassium channels as therapeutic targets
- (2009) Heike Wulff et al. NATURE REVIEWS DRUG DISCOVERY
- Erg K+ currents modulate excitability in mouse mitral/tufted neurons
- (2009) Wiebke Hirdes et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Antiarrhythmic properties of a rapid delayed-rectifier current activator in rabbit models of acquired long QT syndrome
- (2008) Thomas G. Diness et al. CARDIOVASCULAR RESEARCH
- Homozygous Missense N629D hERG (KCNH2) Potassium Channel Mutation Causes Developmental Defects in the Right Ventricle and Its Outflow Tract and Embryonic Lethality
- (2008) Guo Qi Teng et al. CIRCULATION RESEARCH
- Targeting Ion Channels in Cancer: A Novel Frontier in Antineoplastic Therapy
- (2008) A. Arcangeli et al. CURRENT MEDICINAL CHEMISTRY
- Silencing of herg gene by shRNA inhibits SH-SY5Y cell growth in vitro and in vivo
- (2007) Jie Zhao et al. EUROPEAN JOURNAL OF PHARMACOLOGY
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