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Title
hERG K+ Channels: Structure, Function, and Clinical Significance
Authors
Keywords
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Journal
PHYSIOLOGICAL REVIEWS
Volume 92, Issue 3, Pages 1393-1478
Publisher
American Physiological Society
Online
2012-07-19
DOI
10.1152/physrev.00036.2011
References
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- Computational analysis of the effects of the hERG channel opener NS1643 in a human ventricular cell model
- (2008) Torben Peitersen et al. HEART RHYTHM
- Cellular basis for arrhythmogenesis in an experimental model of the SQT1 form of the short QT syndrome
- (2008) Chinmay Patel et al. HEART RHYTHM
- Recurrent intrauterine fetal loss due to near absence of HERG: Clinical and functional characterization of a homozygous nonsense HERG Q1070X mutation
- (2008) Zahurul A. Bhuiyan et al. HEART RHYTHM
- A KCNH2 branch point mutation causing aberrant splicing contributes to an explanation of genotype-negative long QT syndrome
- (2008) Lia Crotti et al. HEART RHYTHM
- A novel KCNH2 mutation as a modifier for short QT interval
- (2008) Hideki Itoh et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- The Pore Domain Outer Helix Contributes to Both Activation and Inactivation of the hERG K+Channel
- (2008) Pengchu Ju et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Small GTPase Determinants for the Golgi Processing and Plasmalemmal Expression of Human Ether-a-go-go Related (hERG) K+Channels
- (2008) Brian P. Delisle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- hERG Gating Microdomains Defined by S6 Mutagenesis and Molecular Modeling
- (2008) Sarah L. Wynia-Smith et al. JOURNAL OF GENERAL PHYSIOLOGY
- A-Kinase Anchoring Protein Targeting of Protein Kinase A and Regulation of HERG Channels
- (2008) Yan Li et al. JOURNAL OF MEMBRANE BIOLOGY
- A splice site mutation in hERG leads to cryptic splicing in human long QT syndrome
- (2008) Qiuming Gong et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Genetic screening in C. elegans identifies rho-GTPase activating protein 6 as novel HERG regulator
- (2008) Franck Potet et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Delayed-rectifier potassium currents and the control of cardiac repolarization: Noble and Tsien 40 years after
- (2008) Stanley Nattel JOURNAL OF PHYSIOLOGY-LONDON
- ERG voltage-gated K+channels regulate excitability and discharge dynamics of the medial vestibular nucleus neurones
- (2008) Mauro Pessia et al. JOURNAL OF PHYSIOLOGY-LONDON
- hERG Classification Model Based on a Combination of Support Vector Machine Method and GRIND Descriptors
- (2008) Qiyuan Li et al. MOLECULAR PHARMACEUTICS
- Topological Mapping of the Asymmetric Drug Binding to the Human Ether-a-go-go-Related Gene Product (HERG) Potassium Channel by Use of Tandem Dimers
- (2008) T. Myokai et al. MOLECULAR PHARMACOLOGY
- Drug Binding to the Inactivated State Is Necessary but Not Sufficient for High-Affinity Binding to Human Ether-a-go-go-Related Gene Channels
- (2008) M. J. Perrin et al. MOLECULAR PHARMACOLOGY
- One step at a time: endoplasmic reticulum-associated degradation
- (2008) Shruthi S. Vembar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Identification of a possible pathogenic link between congenital long QT syndrome and epilepsy
- (2008) J. N. Johnson et al. NEUROLOGY
- Preclinical Torsades-de-Pointes Screens: Advantages and limitations of surrogate and direct approaches in evaluating proarrhythmic risk
- (2008) Gary A. Gintant PHARMACOLOGY & THERAPEUTICS
- The hERG potassium channel and hERG screening for drug-induced torsades de pointes
- (2008) Jules C. Hancox et al. PHARMACOLOGY & THERAPEUTICS
- The human ERG1 channel polymorphism, K897T, creates a phosphorylation site that inhibits channel activity
- (2008) S. Gentile et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A novel nonsense mutation Y652X in the S6/pore region of human ether-go-go gene found in a long QT syndrome family
- (2008) Yaxun Sun et al. SCANDINAVIAN CARDIOVASCULAR JOURNAL
- Coexistence of hERG current block and disruption of protein trafficking in ketoconazole-induced long QT syndrome
- (2007) H Takemasa et al. BRITISH JOURNAL OF PHARMACOLOGY
- State dependent dissociation of HERG channel inhibitors
- (2007) D Stork et al. BRITISH JOURNAL OF PHARMACOLOGY
- A Composite Model for hERG Blockade
- (2007) Christian Kramer et al. ChemMedChem
- Modeling the hERG potassium channel in a phospholipid bilayer: Molecular dynamics and drug docking studies
- (2007) Matteo Masetti et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Evaluation of zebrafish embryos as a model for assessing inhibition of hERG
- (2007) S.W. Mittelstadt et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
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