Herg K+ Channel-Dependent Apoptosis and Cell Cycle Arrest in Human Glioblastoma Cells

Regulation of apoptosis in HL-1 cardiomyocytes by phosphorylation of the receptor tyrosine kinase EphA2 and protection by lithocholic acid

(2012) J Jehle et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K+channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells

(2012) J Jehle et al.   BRITISH JOURNAL OF PHARMACOLOGY

Standards of care for treatment of recurrent glioblastoma—are we there yet?

(2012) Michael Weller et al.   NEURO-ONCOLOGY

Gene therapy for brain tumors: Basic developments and clinical implementation

(2012) Hikmat Assi et al.   NEUROSCIENCE LETTERS

A Small Molecule Agonist of EphA2 Receptor Tyrosine Kinase Inhibits Tumor Cell Migration In Vitro and Prostate Cancer Metastasis In Vivo

(2012) Aaron Petty et al.   PLoS One

Connexin 43 gene therapy prevents persistent atrial fibrillation in a porcine model

(2011) Olympia Bikou et al.   CARDIOVASCULAR RESEARCH

Suppression of persistent atrial fibrillation by genetic knockdown of caspase 3: a pre-clinical pilot study

(2011) Kerstin Trappe et al.   EUROPEAN HEART JOURNAL

Genetic suppression of atrial fibrillation using a dominant-negative ether-a-go-go–related gene mutant

(2011) Radim Soucek et al.   HEART RHYTHM

Molecular determinants of hERG potassium channel inhibition by disopyramide

(2011) Aziza El Harchi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells

(2011) Günter Glassmeier et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Novel roles for hERG K+ channels in cell proliferation and apoptosis

(2011) J Jehle et al.   Cell Death & Disease

Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine

(2010) Sabrina Obers et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

hERG K+ channel-associated cardiac effects of the antidepressant drug desipramine

(2010) Ingo Staudacher et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Role of potassium currents in cardiac arrhythmias

(2008) U. Ravens et al.   EUROPACE

Enzastaurin-induced apoptosis in glioma cells is caspase-dependent and inhibited by BCL-XL

(2008) Johannes Rieger et al.   JOURNAL OF NEUROCHEMISTRY

The EphA2 Receptor and EphrinA1 Ligand in Solid Tumors: Function and Therapeutic Targeting

(2008) J. Wykosky et al.   MOLECULAR CANCER RESEARCH

Doxazosin induces apoptosis of cells expressing hERG K+ channels

(2007) Dierk Thomas et al.   EUROPEAN JOURNAL OF PHARMACOLOGY