TRPV1 channel as a target for cancer therapy using CNT-based drug delivery systems

(−)-Englerin A is a Potent and Selective Activator of TRPC4 and TRPC5 Calcium Channels

(2015) Yasemin Akbulut et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular dynamics simulations of large macromolecular complexes

(2015) Juan R Perilla et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Computer-Aided Drug Discovery Approach Finds Calcium Sensitizer of Cardiac Troponin

(2014) Steffen Lindert et al.   Chemical Biology & Drug Design

A Molecular Dynamics Investigation ofMycobacterium tuberculosisPrenyl Synthases: Conformational Flexibility and Implications for Computer-aided Drug Discovery

(2014) Meekyum Olivia Kim et al.   Chemical Biology & Drug Design

Pharmacodynamics of TRPV1 Agonists in a Bioassay Using Human PC-3 Cells

(2014) Daniel Alvarez-Berdugo et al.   TheScientificWorldJOURNAL

Bladder Cancer and Urothelial Impairment: The Role of TRPV1 as Potential Drug Target

(2014) Francesco Mistretta et al.   Biomed Research International

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

(2013) Sander Pronk et al.   BIOINFORMATICS

Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314

(2013) Michelino Puopolo et al.   JOURNAL OF NEUROPHYSIOLOGY

Dynamics of Fullerene-Mediated Heat-Driven Release of Drug Molecules from Carbon Nanotubes

(2013) Nabanita Saikia et al.   Journal of Physical Chemistry Letters

Epitope Fluctuations in the Human Papillomavirus Are Under Dynamic Allosteric Control: A Computational Evaluation of a New Vaccine Design Strategy

(2013) Abhishek Singharoy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interactions of Doxorubicin with Organized Interfacial Assemblies. 1. Electrochemical Characterization

(2013) Dorota Nieciecka et al.   LANGMUIR

Effect of Cholesterol Depletion on the Pore Dilation of TRPV1

(2013) Erik T Jansson et al.   Molecular Pain

TRPV1 structures in distinct conformations reveal activation mechanisms

(2013) Erhu Cao et al.   NATURE

Molecular dynamics simulation study of the vanillate transport channel of Opdk

(2012) Yibo Wang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Functionalized carbon nanotubes: biomedical applications

(2012) Shree Singh et al.   International Journal of Nanomedicine

N-Glycosylation Determines Ionic Permeability and Desensitization of the TRPV1 Capsaicin Receptor

(2012) Nicholas A. Veldhuis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LAMBADA and InflateGRO2: Efficient Membrane Alignment and Insertion of Membrane Proteins for Molecular Dynamics Simulations

(2012) Thomas H. Schmidt et al.   Journal of Chemical Information and Modeling

Multifunctional Branched Gold–Carbon Nanotube Hybrid for Cell Imaging and Drug Delivery

(2012) L. Minati et al.   LANGMUIR

Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1

(2012) Kristin Stock et al.   NATURE MEDICINE

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

(2012) T. Eicher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRP channels: diagnostic markers and therapeutic targets for breast cancer?

(2012) Halima Ouadid-Ahidouch et al.   TRENDS IN MOLECULAR MEDICINE

TRP Channels and Cancer: New Targets for Diagnosis and Chemotherapy

(2012) Giorgio Santoni et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Recent advances in apoptosis, mitochondria and drug resistance in cancer cells

(2011) Inthrani R. Indran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

(2011) Roman A. Laskowski et al.   Journal of Chemical Information and Modeling

Binding of blood proteins to carbon nanotubes reduces cytotoxicity

(2011) C. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activity-dependent targeting of TRPV1 with a pore-permeating capsaicin analog

(2011) H. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The application of carbon nanotubes in target drug delivery systems for cancer therapies

(2011) Wuxu Zhang et al.   Nanoscale Research Letters

Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation

(2010) T. G. Banke et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain

(2010) Christopher J. Bohlen et al.   CELL

g_wham—A Free Weighted Histogram Analysis Implementation Including Robust Error and Autocorrelation Estimates

(2010) Jochen S. Hub et al.   Journal of Chemical Theory and Computation

How do carbon nanotubes serve as carriers for gemcitabine transport in a drug delivery system?

(2010) Uthumporn Arsawang et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Irritating channels: the case of TRPA1

(2010) Bernd Nilius et al.   JOURNAL OF PHYSIOLOGY-LONDON

Clinical Developments in Nanotechnology for Cancer Therapy

(2010) Jeremy D. Heidel et al.   PHARMACEUTICAL RESEARCH

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Abnormal expression, localization and interaction of canonical transient receptor potential ion channels in human breast cancer cell lines and tissues: a potential target for breast cancer diagnosis and therapy

(2009) Ebru Aydar et al.   Cancer Cell International

Current advances in research and clinical applications of PLGA-based nanotechnology

(2009) Jian-Ming Lü et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

United Atom Lipid Parameters for Combination with the Optimized Potentials for Liquid Simulations All-Atom Force Field

(2009) Jakob P. Ulmschneider et al.   Journal of Chemical Theory and Computation

MKTOP: a program for automatic construction of molecular topologies

(2008) André A. S. T. Ribeiro et al.   JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY

Fire in the hole: pore dilation of the capsaicin receptor TRPV1

(2008) Diana Bautista et al.   NATURE NEUROSCIENCE

TRPV1 shows dynamic ionic selectivity during agonist stimulation

(2008) Man-Kyo Chung et al.   NATURE NEUROSCIENCE

Probing the Structure of DNA−Carbon Nanotube Hybrids with Molecular Dynamics

(2007) Robert R. Johnson et al.   NANO LETTERS