Loss of Camk2n1 aggravates cardiac remodeling and malignant ventricular arrhythmia after myocardial infarction in mice via NLRP3 inflammasome activation

Dendritic Cell-Restricted Progenitors Contribute to Obesity-Associated Airway Inflammation via Adam17-p38 MAPK-Dependent Pathway

(2020) Anil Kumar Jaiswal et al.   Frontiers in Immunology

Inhibition of mast cell tryptase attenuates neuroinflammation via PAR-2/p38/NFκB pathway following asphyxial cardiac arrest in rats

(2020) Umut Ocak et al.   Journal of Neuroinflammation

CaMKII inhibitor 1 (CaMK2N1) mRNA is upregulated following LTP induction in hippocampal slices

(2020) Daniela Astudillo et al.   SYNAPSE

Ethanol-activated CaMKII signaling induces neuronal apoptosis through Drp1-mediated excessive mitochondrial fission and JNK1-dependent NLRP3 inflammasome activation

(2020) Jae Ryong Lim et al.   Cell Communication and Signaling

Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Post-Operative Atrial Fibrillation

(2020) Jordi Heijman et al.   CIRCULATION RESEARCH

Therapeutic modulation of inflammasome pathways

(2020) Dhruv Chauhan et al.   IMMUNOLOGICAL REVIEWS

Silenced SOX2‐OT alleviates ventricular arrhythmia associated with heart failure by inhibiting NLRP3 expression via regulating miR‐2355‐3p

(2020) Yuming Liang et al.   Immunity Inflammation and Disease

Inflammation and NLRP3 Inflammasome Activation Initiated in Response to Pressure Overload by Ca 2+ /Calmodulin-Dependent Protein Kinase II δ Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling

(2019) Takeshi Suetomi et al.   CIRCULATION

Camk2n1 Is a Negative Regulator of Blood Pressure, Left Ventricular Mass, Insulin Sensitivity, and Promotes Adiposity

(2019) Neza Alfazema et al.   HYPERTENSION

β-Arrestin 2 mediates arginine vasopressin-induced IL-6 induction via the ERK1/2-NF-κB signal pathway in murine hearts

(2019) Shu-zhen Sun et al.   ACTA PHARMACOLOGICA SINICA

DPP-4 inhibition by linagliptin prevents cardiac dysfunction and inflammation by targeting the Nlrp3/ASC inflammasome

(2019) Yochai Birnbaum et al.   BASIC RESEARCH IN CARDIOLOGY

The selective NLRP3-inflammasome inhibitor MCC950 reduces myocardial fibrosis and improves cardiac remodeling in a mouse model of myocardial infarction

(2019) Rifeng Gao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

MiR‐129‐5p promotes docetaxel resistance in prostate cancer by down‐regulating CAMK2N1 expression

(2019) Cheng Wu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Risk Stratification for Sudden Cardiac Death After Myocardial Infarction

(2018) Jonathan W. Waks et al.   Annual Review of Medicine

Losmapimod Overcomes Gefitinib Resistance in Non-small Cell Lung Cancer by Preventing Tetraploidization

(2018) Yiu To Yeung et al.   EBioMedicine

Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

(2018) Hans Erik Bøtker et al.   BASIC RESEARCH IN CARDIOLOGY

Inhibition of JNK and p38 MAPK-mediated inflammation and apoptosis by ivabradine improves cardiac function in streptozotocin-induced diabetic cardiomyopathy

(2018) Guangfeng Zuo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression

(2018) Belal A. Mohamed et al.   Science Translational Medicine

Interleukin-18: Biological properties and role in disease pathogenesis

(2017) Gilles Kaplanski   IMMUNOLOGICAL REVIEWS

Haplodeficiency of activin receptor-like kinase 4 alleviates myocardial infarction-induced cardiac fibrosis and preserves cardiac function

(2017) Yi-He Chen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Acute myocardial infarction

(2017) Grant W Reed et al.   LANCET

The NLRP3 inflammasome in acute myocardial infarction

(2017) Stefano Toldo et al.   Nature Reviews Cardiology

CaMKII as a target for arrhythmia suppression

(2017) Julian Mustroph et al.   PHARMACOLOGY & THERAPEUTICS

Cardiac Fibroblast Activation Post-Myocardial Infarction: Current Knowledge Gaps

(2017) Yonggang Ma et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The Biological Basis for Cardiac Repair After Myocardial Infarction

(2016) Sumanth D. Prabhu et al.   CIRCULATION RESEARCH

Inflammation as a Driver of Adverse Left Ventricular Remodeling After Acute Myocardial Infarction

(2016) Peter C. Westman et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress–induced myocardial necroptosis

(2016) Ting Zhang et al.   NATURE MEDICINE

The Inflammasome in Myocardial Injury and Cardiac Remodeling

(2015) Stefano Toldo et al.   ANTIOXIDANTS & REDOX SIGNALING

Oestrogen inhibits BMP4-induced BMP4 expression in cardiomyocytes: a potential mechanism of oestrogen-mediated protection against cardiac hypertrophy

(2015) Yu-Chun Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Calcium/Calmodulin-Dependent Protein Kinase II and Its Endogenous Inhibitor   in Medullary Thyroid Cancer

(2014) E. Russo et al.   CLINICAL CANCER RESEARCH

CaM Kinase II mediates maladaptive post-infarct remodeling and pro-inflammatory chemoattractant signaling but not acute myocardial ischemia/reperfusion injury

(2014) M. Weinreuter et al.   EMBO Molecular Medicine

The inflammatory response in myocardial injury, repair and remodelling

(2014) Nikolaos G. Frangogiannis   Nature Reviews Cardiology

Cardiac electrical remodeling in health and disease

(2011) Michael J. Cutler et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Spatiotemporal Regulation of Multiple Overlapping Sense and Novel Natural Antisense Transcripts at the Nrgn and Camk2n1 Gene Loci during Mouse Cerebral Corticogenesis

(2010) King-Hwa Ling et al.   CEREBRAL CORTEX

Mouse strain determines the outcome of wound healing after myocardial infarction

(2009) Susanne W.M. van den Borne et al.   CARDIOVASCULAR RESEARCH

Angiotensin II–Induced Oxidative Stress Resets the Ca 2+ Dependence of Ca 2+ –Calmodulin Protein Kinase II and Promotes a Death Pathway Conserved Across Different Species

(2009) Julieta Palomeque et al.   CIRCULATION RESEARCH

Myocardial remodeling after infarction: the role of myofibroblasts

(2009) Susanne W. M. van den Borne et al.   Nature Reviews Cardiology