Camk2n1 Is a Negative Regulator of Blood Pressure, Left Ventricular Mass, Insulin Sensitivity, and Promotes Adiposity

Deletion of Angiotensin-Converting Enzyme-2 Promotes Hypertensive Nephropathy by Targeting Smad7 for Ubiquitin DegradationNovelty and Significance

(2017) Zhen Liu et al.   HYPERTENSION

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

(2017) Helen R Warren et al.   NATURE GENETICS

Towards Precision Medicine for Hypertension: A Review of Genomic, Epigenomic, and Microbiomic Effects on Blood Pressure in Experimental Rat Models and Humans

(2017) Sandosh Padmanabhan et al.   PHYSIOLOGICAL REVIEWS

Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling

(2017) Connor A. Emdin et al.   CIRCULATION

Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity

(2017) Shubha Murthy et al.   PLoS One

Plasma Levels of Fatty Acid–Binding Protein 4, Retinol-Binding Protein 4, High-Molecular-Weight Adiponectin, and Cardiovascular Mortality Among Men With Type 2 DiabetesHighlights

(2016) Gang Liu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Framingham Heart Study — 67 years of discovery in metabolic disease

(2016) Michelle T. Long et al.   Nature Reviews Endocrinology

Cardiomyocyte Overexpression of FABP4 Aggravates Pressure Overload-Induced Heart Hypertrophy

(2016) Ji Zhang et al.   PLoS One

Calcium/Calmodulin-Dependent Kinase II Inhibition in Smooth Muscle Reduces Angiotensin II-Induced Hypertension by Controlling Aortic Remodeling and Baroreceptor Function

(2015) A. M. Prasad et al.   Journal of the American Heart Association

The Adipocyte-Inducible Secreted Phospholipases PLA2G5 and PLA2G2E Play Distinct Roles in Obesity

(2014) Hiroyasu Sato et al.   Cell Metabolism

Cardiac CaM Kinase II Genes δ and γ Contribute to Adverse Remodeling but Redundantly Inhibit Calcineurin-Induced Myocardial Hypertrophy

(2014) Michael M. Kreusser et al.   CIRCULATION

The Rat Genome Database 2015: genomic, phenotypic and environmental variations and disease

(2014) Mary Shimoyama et al.   NUCLEIC ACIDS RESEARCH

CaMKII inhibitors: from research tools to therapeutic agents

(2014) Patricia Pellicena et al.   Frontiers in Pharmacology

State of the art paper Biochemistry of adipose tissue: an endocrine organ

(2013) Marisa Coelho et al.   Archives of Medical Science

Activation of Calcium/Calmodulin-Dependent Protein Kinase II in Obesity Mediates Suppression of Hepatic Insulin Signaling

(2013) Lale Ozcan et al.   Cell Metabolism

Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes

(2013) H. Yaghootkar et al.   DIABETES

Differential Control of Calcium Homeostasis and Vascular Reactivity by Ca 2+ /Calmodulin-Dependent Kinase II

(2013) Anand M. Prasad et al.   HYPERTENSION

Systems-level approaches reveal conservation of trans-regulated genes in the rat and genetic determinants of blood pressure in humans

(2012) Sarah R. Langley et al.   CARDIOVASCULAR RESEARCH

Angiotensin-(1–7): beyond the cardio-renal actions

(2012) Danielle G. Passos-Silva et al.   CLINICAL SCIENCE

An Inhibitor of Phospholipase A2 Group IIA Modulates Adipocyte Signaling and Protects Against Diet-Induced Metabolic Syndrome in Rats

(2012) A. Iyer et al.   DIABETES

Association of ACE2 Genetic Variants With Blood Pressure, Left Ventricular Mass, and Cardiac Function in Caucasians With Type 2 Diabetes

(2011) S. K. Patel et al.   AMERICAN JOURNAL OF HYPERTENSION

Up-regulation of p27kip1 contributes to Nrf2-mediated protection against angiotensin II-induced cardiac hypertrophy

(2011) Jinqing Li et al.   CARDIOVASCULAR RESEARCH

Integrated genomic approaches to identification of candidate genes underlying metabolic and cardiovascular phenotypes in the spontaneously hypertensive rat

(2011) Catherine Morrissey et al.   PHYSIOLOGICAL GENOMICS

Calmodulin kinase II is required for angiotensin II-mediated vascular smooth muscle hypertrophy

(2009) Hui Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Adiponectin Levels and Risk of Type 2 Diabetes

(2009) Shanshan Li et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

CaMKII-Mediated Phosphorylation of the Myosin Motor Myo1c Is Required for Insulin-Stimulated GLUT4 Translocation in Adipocytes

(2008) Ming Fai Yip et al.   Cell Metabolism

The Helix–Loop–Helix Factors Id3 and E47 Are Novel Regulators of Adiponectin

(2008) Amanda C. Doran et al.   CIRCULATION RESEARCH

Progress and prospects in rat genetics: a community view

(2008) Timothy J Aitman et al.   NATURE GENETICS