Ethanol-activated CaMKII signaling induces neuronal apoptosis through Drp1-mediated excessive mitochondrial fission and JNK1-dependent NLRP3 inflammasome activation
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Ethanol-activated CaMKII signaling induces neuronal apoptosis through Drp1-mediated excessive mitochondrial fission and JNK1-dependent NLRP3 inflammasome activation
Authors
Keywords
-
Journal
Cell Communication and Signaling
Volume 18, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-08-12
DOI
10.1186/s12964-020-00572-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Inflammation and NLRP3 Inflammasome Activation Initiated in Response to Pressure Overload by Ca 2+ /Calmodulin-Dependent Protein Kinase II δ Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling
- (2019) Takeshi Suetomi et al. CIRCULATION
- Dynamics of Dynamin-Related Protein 1 in Alzheimer’s Disease and Other Neurodegenerative Diseases
- (2019) Darryll Oliver et al. Cells
- Dynamin-related protein 1: A protein critical for mitochondrial fission, mitophagy, and neuronal death in Parkinson’s disease
- (2019) Si-Tong Feng et al. PHARMACOLOGICAL RESEARCH
- Mitophagy Plays a Protective Role in Iodinated Contrast-Induced Acute Renal Tubular Epithelial Cells Injury
- (2018) Rong Lei et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Mitochondrial dynamics: overview of molecular mechanisms
- (2018) Lisa Tilokani et al. Essays in Biochemistry
- Posttranslational Regulation of the NLR Family Pyrin Domain-Containing 3 Inflammasome
- (2018) Do-Wan Shim et al. Frontiers in Immunology
- Mitochondrial Morphology, Function and Homeostasis Are Impaired by Expression of an N-terminal Calpain Cleavage Fragment of Ataxin-3
- (2018) Tina Harmuth et al. Frontiers in Molecular Neuroscience
- NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation
- (2017) Nan Song et al. MOLECULAR CELL
- A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance
- (2017) Babette C. Hammerling et al. Nature Communications
- Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis
- (2016) Dah Ihm Kim et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Melatonin prevents abnormal mitochondrial dynamics resulting from the neurotoxicity of cadmium by blocking calcium-dependent translocation of Drp1 to the mitochondria
- (2016) Shangcheng Xu et al. JOURNAL OF PINEAL RESEARCH
- CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation
- (2016) Shangcheng Xu et al. Nature Communications
- Quercetin Attenuates Chronic Ethanol-Induced Hepatic Mitochondrial Damage through Enhanced Mitophagy
- (2016) Xiao Yu et al. Nutrients
- Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells
- (2016) Lidia De Filippis et al. Molecular Brain
- Carvacrol protects neuroblastoma SH-SY5Y cells against Fe2+-induced apoptosis by suppressing activation of MAPK/JNK-NF-κB signaling pathway
- (2015) Zhen-wen Cui et al. ACTA PHARMACOLOGICA SINICA
- Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in mice
- (2015) Jessica A. Williams et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- On the mechanism underlying ethanol-induced mitochondrial dynamic disruption and autophagy response
- (2015) Luis Bonet-Ponce et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Dynamin-related Protein 1 Oligomerization in Solution Impairs Functional Interactions with Membrane-anchored Mitochondrial Fission Factor
- (2015) Ryan W. Clinton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ethanol directly induced HMGB1 release through NOX2/NLRP1 inflammasome in neuronal cells
- (2015) Xiaolan Wang et al. TOXICOLOGY
- Mitochondria: diversity in the regulation of the NLRP3 inflammasome
- (2015) Prajwal Gurung et al. TRENDS IN MOLECULAR MEDICINE
- Ethanol Upregulates NMDA Receptor Subunit Gene Expression in Human Embryonic Stem Cell-Derived Cortical Neurons
- (2015) Yangfei Xiang et al. PLoS One
- Intravenous Immunoglobulin Treatment in Humans Suppresses Dendritic Cell Function via Stimulation of IL-4 and IL-13 Production
- (2014) A. S. W. Tjon et al. JOURNAL OF IMMUNOLOGY
- Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy
- (2014) J. Yu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of mitochondria ROS generation in ethanol-induced NLRP3 inflammasome activation and cell death in astroglial cells
- (2014) Silvia Alfonso-Loeches et al. Frontiers in Cellular Neuroscience
- Autophagy and mitochondrial alterations in human retinal pigment epithelial cells induced by ethanol: implications of 4-hydroxy-nonenal
- (2014) M Flores-Bellver et al. Cell Death & Disease
- Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity
- (2013) Hideki Hara et al. NATURE IMMUNOLOGY
- Minimal NF-κB activity in neurons
- (2013) S.J. Listwak et al. NEUROSCIENCE
- P2X7 Cell Death Receptor Activation and Mitochondrial Impairment in Oxaliplatin-Induced Apoptosis and Neuronal Injury: Cellular Mechanisms and In Vivo Approach
- (2013) France Massicot et al. PLoS One
- Microglial activation of the NLRP3 inflammasome by the priming signals derived from macrophages infected with mycobacteria
- (2012) Hye-Mi Lee et al. GLIA
- Dynamic Adaptation of Liver Mitochondria to Chronic Alcohol Feeding in Mice
- (2012) Derick Han et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intracellular calcium plays a critical role in the alcohol-mediated death of cerebellar granule neurons
- (2012) Dimitrios E. Kouzoukas et al. JOURNAL OF NEUROCHEMISTRY
- The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation
- (2012) Fushan Shi et al. Journal of Neuroinflammation
- The Anti-inflammatory Effect of Melatonin on Methamphetamine-Induced Proinflammatory Mediators in Human Neuroblastoma Dopamine SH-SY5Y Cell Lines
- (2012) Kannika Permpoonputtana et al. NEUROTOXICITY RESEARCH
- Critical role for calcium mobilization in activation of the NLRP3 inflammasome
- (2012) T. Murakami et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Caspase-1-induced pyroptotic cell death
- (2011) Edward A. Miao et al. IMMUNOLOGICAL REVIEWS
- Mycobacterium abscessus activates the NLRP3 inflammasome via Dectin-1-Syk and p62/SQSTM1
- (2011) Hye-Mi Lee et al. IMMUNOLOGY AND CELL BIOLOGY
- Calcium-dependent mitochondrial function and dysfunction in neurons
- (2010) Natalia B. Pivovarova et al. FEBS Journal
- Biochemical and Neurotransmitter Changes Implicated in Alcohol-Induced Brain Damage in Chronic or 'Binge Drinking' Alcohol Abuse
- (2009) R. J. Ward et al. ALCOHOL AND ALCOHOLISM
- IL-1β induces MMP-9 expression via a Ca2+-dependent CaMKII/JNK/c-JUN cascade in rat brain astrocytes
- (2009) Cheng-Ying Wu et al. GLIA
- Impact of Alcohol Abuse on Protein Expression of Midkine and Excitatory Amino Acid Transporter 1 in the Human Prefrontal Cortex
- (2008) Traute Flatscher-Bader et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- CaM kinase Iα–induced phosphorylation of Drp1 regulates mitochondrial morphology
- (2008) Xiao-Jian Han et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial fragmentation in neurodegeneration
- (2008) Andrew B. Knott et al. NATURE REVIEWS NEUROSCIENCE
- Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria
- (2008) G. M. Cereghetti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More