Aging lens epithelium is susceptible to ferroptosis

Ferroptosis: mechanisms, biology and role in disease

(2021) Xuejun Jiang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ferroptosis: past, present and future

(2020) Jie Li et al.   Cell Death & Disease

Ferroptosis in Cancer Cell Biology

(2020) Christina M. Bebber et al.   Cancers

Lipid peroxidation and ferroptosis: The role of GSH and GPx4

(2020) Fulvio Ursini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vitamin C is a source of oxoaldehyde and glycative stress in age‐related cataract and neurodegenerative diseases

(2020) Xingjun Fan et al.   AGING CELL

Emerging Mechanisms and Disease Relevance of Ferroptosis

(2020) Brent R. Stockwell et al.   TRENDS IN CELL BIOLOGY

The Mechanism of Ferroptosis and Applications in Tumor Treatment

(2020) Xinyue Lin et al.   Frontiers in Pharmacology

Synchrotron-based FTIR microspectroscopy of protein aggregation and lipids peroxidation changes in human cataractous lens epithelial cells

(2020) Martin Kreuzer et al.   Scientific Reports

Ferroptosis Mechanisms Involved in Neurodegenerative Diseases

(2020) Cadiele Oliana Reichert et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanisms of Ferroptosis and Relations With Regulated Cell Death: A Review

(2019) Pengxu Lei et al.   Frontiers in Physiology

Ferroptosis as a target for protection against cardiomyopathy

(2019) Xuexian Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of H2A ubiquitination and SLC7A11 expression by BAP1 and PRC1

(2019) Yilei Zhang et al.   CELL CYCLE

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

Mitochondria regulation in ferroptosis

(2019) Hai Wang et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Comprehensive expression patterns of inflammatory cytokines in aqueous humor of patients with neovascular age-related macular degeneration

(2019) Tomohito Sato et al.   Scientific Reports

Serum selenium levels are associated with age-related cataract

(2018) Michał Post et al.   ANNALS OF AGRICULTURAL AND ENVIRONMENTAL MEDICINE

Transferrin and transferrin receptors update

(2018) Hiroshi Kawabata   FREE RADICAL BIOLOGY AND MEDICINE

BECN1 is a new driver of ferroptosis

(2018) Rui Kang et al.   Autophagy

Prion Protein Regulates Iron Transport by Functioning as a Ferrireductase

(2018) Ajay Singh et al.   JOURNAL OF ALZHEIMERS DISEASE

Increased Iron Levels and Decreased Tissue Integrity in Hippocampus of Alzheimer's Disease Detected in vivo with Magnetic Resonance Imaging

(2018) Erika P. Raven et al.   JOURNAL OF ALZHEIMERS DISEASE

Aqueous humor cytokine levels in patients with diabetic macular edema refractory to anti-VEGF treatment

(2018) Jin-woo Kwon et al.   PLoS One

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

(2017) Vasanthi S. Viswanathan et al.   NATURE

Cell death pattern in lens epithelium of cataract patients

(2016) Øyvind Osnes-Ringen et al.   ACTA OPHTHALMOLOGICA

The oxidized thiol proteome in aging and cataractous mouse and human lens revealed by ICAT labeling

(2016) Benlian Wang et al.   AGING CELL

Iron Homeostasis in Health and Disease

(2016) Raffaella Gozzelino et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Selenite and ebselen supplementation attenuates d-galactose-induced oxidative stress and increases expression of SELR and SEP15 in rat lens

(2016) Jie Dai et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Ironing out Ferroportin

(2015) Hal Drakesmith et al.   Cell Metabolism

Evidence of Highly Conserved β-Crystallin Disulfidome that Can be Mimicked byIn VitroOxidation in Age-related Human Cataract and Glutathione Depleted Mouse Lens

(2015) Xingjun Fan et al.   MOLECULAR & CELLULAR PROTEOMICS

The role of lipoxygenases in pathophysiology; new insights and future perspectives

(2015) Ryuichi Mashima et al.   Redox Biology

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase

(2014) A. G. Frey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

ZIP8 Is an Iron and Zinc Transporter Whose Cell-surface Expression Is Up-regulated by Cellular Iron Loading

(2012) Chia-Yu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The LEGSKO Mouse: A Mouse Model of Age-Related Nuclear Cataract Based on Genetic Suppression of Lens Glutathione Synthesis

(2012) Xingjun Fan et al.   PLoS One

Instability of the cellular lipidome with age

(2011) Jessica R. Hughes et al.   AGE

Ferritin and metallothionein: dangerous liaisons

(2011) Ruben Orihuela et al.   CHEMICAL COMMUNICATIONS

The lens as a model for fibrotic disease

(2011) J. A. Eldred et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Anaerobic vs aerobic pathways of carbonyl and oxidant stress in human lens and skin during aging and in diabetes: A comparative analysis

(2010) Xingjun Fan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lipids and the ocular lens

(2010) Douglas Borchman et al.   JOURNAL OF LIPID RESEARCH

Oxidative Damage and the Prevention of Age-Related Cataracts

(2010) David C. Beebe et al.   OPHTHALMIC RESEARCH

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY