Silencing of STE20‐type kinase MST3 in mice with antisense oligonucleotide treatment ameliorates diet‐induced nonalcoholic fatty liver disease
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Silencing of STE20‐type kinase MST3 in mice with antisense oligonucleotide treatment ameliorates diet‐induced nonalcoholic fatty liver disease
Authors
Keywords
-
Journal
FASEB JOURNAL
Volume 35, Issue 5, Pages -
Publisher
Wiley
Online
2021-04-24
DOI
10.1096/fj.202002671rr
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Acetyl-CoA carboxylase 1 and 2 inhibition ameliorates steatosis and hepatic fibrosis in a MC4R knockout murine model of nonalcoholic steatohepatitis
- (2020) Mitsuharu Matsumoto et al. PLoS One
- Antisense Oligonucleotides Targeting Jagged 1 Reduce House Dust Mite-Induced Goblet Cell Metaplasia in the Adult Murine Lung
- (2020) Michele Carrer et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Hepatocyte Deletion of Triglyceride‐Synthesis Enzyme DGAT 2 Reduces Steatosis without Increasing Inflammation or Fibrosis
- (2019) Nina L. Gluchowski et al. HEPATOLOGY
- Past, present and future perspectives in nonalcoholic fatty liver disease
- (2019) Arun J. Sanyal Nature Reviews Gastroenterology & Hepatology
- From NASH to HCC: current concepts and future challenges
- (2019) Quentin M. Anstee et al. Nature Reviews Gastroenterology & Hepatology
- Protein kinase MST3 modulates lipid homeostasis in hepatocytes and correlates with nonalcoholic steatohepatitis in humans
- (2019) Emmelie Cansby et al. FASEB JOURNAL
- WZ66, a novel acetyl-CoA carboxylase inhibitor, alleviates nonalcoholic steatohepatitis (NASH) in mice
- (2019) Ying-sheng Gao et al. ACTA PHARMACOLOGICA SINICA
- The Crosstalk between Hepatocytes, Hepatic Macrophages, and Hepatic Stellate Cells Facilitates Alcoholic Liver Disease
- (2019) Tatiana Kisseleva et al. Cell Metabolism
- Lipid droplet-associated kinase STK25 regulates peroxisomal activity and metabolic stress response in steatotic liver
- (2019) Annika Nerstedt et al. JOURNAL OF LIPID RESEARCH
- DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates
- (2018) David G. McLaren et al. Cell Metabolism
- RNA-Targeted Therapeutics
- (2018) Stanley T. Crooke et al. Cell Metabolism
- Acetyl-CoA Carboxylase Inhibitor GS-0976 for 12 Weeks Reduces Hepatic De Novo Lipogenesis and Steatosis in Patients With Nonalcoholic Steatohepatitis
- (2018) Eric J. Lawitz et al. Clinical Gastroenterology and Hepatology
- Current and future therapeutic regimens for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
- (2018) Zobair M. Younossi et al. HEPATOLOGY
- Mechanisms of NAFLD development and therapeutic strategies
- (2018) Scott L. Friedman et al. NATURE MEDICINE
- Triggering and resolution of inflammation in NASH
- (2018) Susanne Schuster et al. Nature Reviews Gastroenterology & Hepatology
- A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease
- (2018) Noura S. Abul-Husn et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma
- (2018) James S.V. Lally et al. Cell Metabolism
- GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease
- (2018) Rohit Loomba et al. GASTROENTEROLOGY
- The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
- (2018) Konstantin Kazankov et al. Nature Reviews Gastroenterology & Hepatology
- The PNPLA3 I148M variant modulates the fibrogenic phenotype of human hepatic stellate cells
- (2017) Francesca Virginia Bruschi et al. HEPATOLOGY
- The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
- (2017) Naga Chalasani et al. HEPATOLOGY
- Lipid zonation and phospholipid remodeling in nonalcoholic fatty liver disease
- (2017) Zoe Hall et al. HEPATOLOGY
- Deficiency in perilipin 5 reduces mitochondrial function and membrane depolarization in mouse hearts
- (2017) Linda Andersson et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRAS
- (2017) Sarah J. Ross et al. Science Translational Medicine
- Molecular Mechanisms of Antisense Oligonucleotides
- (2017) Stanley T. Crooke Nucleic Acid Therapeutics
- STK25 is a critical determinant in nonalcoholic steatohepatitis
- (2016) Manoj Amrutkar et al. FASEB JOURNAL
- Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes
- (2016) Zobair M. Younossi et al. HEPATOLOGY
- Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies
- (2016) Giovanni Musso et al. NATURE REVIEWS DRUG DISCOVERY
- The BUME method: a new rapid and simple chloroform-free method for total lipid extraction of animal tissue
- (2016) Lars Löfgren et al. Scientific Reports
- Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model
- (2015) Manoj Amrutkar et al. DIABETES
- Protein kinase STK25 controls lipid partitioning in hepatocytes and correlates with liver fat content in humans
- (2015) Manoj Amrutkar et al. DIABETOLOGIA
- Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH
- (2015) Manoj Amrutkar et al. FASEB JOURNAL
- Nonalcoholic Steatohepatitis Is the Second Leading Etiology of Liver Disease Among Adults Awaiting Liver Transplantation in the United States
- (2015) Robert J. Wong et al. GASTROENTEROLOGY
- Challenges and opportunities in drug and biomarker development for nonalcoholic steatohepatitis: Findings and recommendations from an American Association for the Study of Liver Diseases-U.S. Food and Drug Administration Joint Workshop
- (2015) Arun J. Sanyal et al. HEPATOLOGY
- AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer
- (2015) David Hong et al. Science Translational Medicine
- PNPLA3 variant I148M is associated with altered hepatic lipid composition in humans
- (2014) Andreas Peter et al. DIABETOLOGIA
- Pathological Features of Fatty Liver Disease
- (2014) Matthew M. Yeh et al. GASTROENTEROLOGY
- Cdk5-Dependent Mst3 Phosphorylation and Activity Regulate Neuronal Migration through RhoA Inhibition
- (2014) J. Tang et al. JOURNAL OF NEUROSCIENCE
- OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin
- (2014) Ligong Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin
- (2013) Morgan D Fullerton et al. NATURE MEDICINE
- Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis
- (2013) Quentin M. Anstee et al. Nature Reviews Gastroenterology & Hepatology
- Characterization of Target mRNA Reduction Through In Situ RNA Hybridization in Multiple Organ Systems Following Systemic Antisense Treatment in Animals
- (2013) Gene Hung et al. Nucleic Acid Therapeutics
- The Problem of Establishing Relationships between Hepatic Steatosis and Hepatic Insulin Resistance
- (2012) Robert V. Farese et al. Cell Metabolism
- Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis
- (2012) Mohamed A. Abdelmegeed et al. JOURNAL OF HEPATOLOGY
- Translocator protein (18kDa), a potential molecular imaging biomarker for non-invasively distinguishing non-alcoholic fatty liver disease
- (2012) Lin Xie et al. JOURNAL OF HEPATOLOGY
- Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
- (2012) Yoshihisa Takahashi WORLD JOURNAL OF GASTROENTEROLOGY
- RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform
- (2010) C. Frank Bennett et al. Annual Review of Pharmacology and Toxicology
- AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3)
- (2010) A. Nerstedt et al. DIABETOLOGIA
- Liver-Specific β-Catenin Knockout Mice Exhibit Defective Bile Acid and Cholesterol Homeostasis and Increased Susceptibility to Diet-Induced Steatohepatitis
- (2009) Jaideep Behari et al. AMERICAN JOURNAL OF PATHOLOGY
- Short Antisense Oligonucleotides with Novel 2′−4′ Conformationaly Restricted Nucleoside Analogues Show Improved Potency without Increased Toxicity in Animals
- (2008) Punit P. Seth et al. JOURNAL OF MEDICINAL CHEMISTRY
- Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
- (2008) Stefano Romeo et al. NATURE GENETICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started