- Home
- Publications
- Publication Search
- Publication Details
Title
Steroid sulfatase inhibitors: the current landscape
Authors
Keywords
-
Journal
EXPERT OPINION ON THERAPEUTIC PATENTS
Volume -, Issue -, Pages 1-20
Publisher
Informa UK Limited
Online
2021-03-30
DOI
10.1080/13543776.2021.1910237
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases
- (2021) Mercedes M. Pérez-Jiménez et al. Nature Communications
- Design and synthesis of dansyl-labeled inhibitors of steroid sulfatase for optical imaging
- (2020) René Maltais et al. BIOORGANIC & MEDICINAL CHEMISTRY
- A new series of aryl sulfamate derivatives: Design, synthesis, and biological evaluation
- (2020) Mohammed I. El-Gamal et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Design and synthesis of 3-benzylaminocoumarin-7-O-sulfamate derivatives as steroid sulfatase inhibitors
- (2020) Yue Hng et al. BIOORGANIC CHEMISTRY
- Estrogen Formation and Inactivation Following TBI: What we Know and Where we Could go
- (2020) Kelli A. Duncan Frontiers in Endocrinology
- New potent steroid sulphatase inhibitors based on 6-(1-phenyl-1H-1,2,3-triazol-4-yl)naphthalen-2-yl sulphamate derivatives
- (2020) Olga Ciupak et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Behavioural and psychiatric phenotypes in female carriers of genetic mutations associated with X-linked ichthyosis
- (2019) Alice Cavenagh et al. PLoS One
- Estrogen sulfotransferase in the metabolism of estrogenic drugs and in the pathogenesis of diseases
- (2019) Anne Caroline S Barbosa et al. Expert Opinion on Drug Metabolism & Toxicology
- Antisulfatase, osteogenic and anticancer activities of steroid sulfatase inhibitor EO-33 in mice
- (2019) Donald Poirier et al. JOURNAL OF MEDICINAL CHEMISTRY
- Adrenal androgens rescue prostatic dihydrotestosterone production and growth of prostate cancer cells after castration
- (2019) Yue Wu et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Expression of genes controlling steroid metabolism and action in granulosa-lutein cells of women with polycystic ovaries
- (2019) A. Lerner et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Novel steroid sulfatase inhibitors based on N ‐thiophosphorylated 3‐(4‐aminophenyl)‐coumarin‐7‐O‐sulfamates
- (2019) Mateusz Daśko et al. DRUG DEVELOPMENT RESEARCH
- Hepatic steroid sulfatase critically determines estrogenic activities of conjugated equine estrogens in human cells in vitro and in mice
- (2019) Ye Feng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 1H NMR-MS-based heterocovariance as a drug discovery tool for fishing bioactive compounds out of a complex mixture of structural analogues
- (2019) Ulrike Grienke et al. Scientific Reports
- Prognostic Relevance of Steroid Sulfation in Adrenocortical Carcinoma Revealed by Molecular Phenotyping Using High-Resolution Mass Spectrometry Imaging
- (2019) Na Sun et al. CLINICAL CHEMISTRY
- The Roles of Sex Hormones in the Course of Atopic Dermatitis
- (2019) Kanda et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Sulfamates in drug design and discovery: Pre-clinical and clinical investigations
- (2019) Seyed-Omar Zaraei et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors
- (2019) Davide Moi et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- New potent STS inhibitors based on fluorinated 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenyl sulfamates
- (2019) Mateusz Daśko et al. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
- Mutual regulations and breast cancer cell control by steroidogenic enzymes: Dual sex-hormone receptor modulation upon 17β-HSD7 inhibition
- (2019) Xiaoye Sang et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Steroid sulfatase inhibiting lanostane triterpenes – Structure activity relationship and in silico insights
- (2019) Ulrike Grienke et al. BIOORGANIC CHEMISTRY
- In breast cancer subtypes steroid sulfatase (STS) is associated with less aggressive tumour characteristics
- (2018) Keely M McNamara et al. BRITISH JOURNAL OF CANCER
- Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure
- (2018) Wolfgang Dohle et al. JOURNAL OF MEDICINAL CHEMISTRY
- SULFATION PATHWAYS: The steroid sulfate axis and its relationship to maternal behaviour and mental health
- (2018) William Davies JOURNAL OF MOLECULAR ENDOCRINOLOGY
- SULFATION PATHWAYS: Steroid sulphatase inhibition via aryl sulphamates: clinical progress, mechanism and future prospects
- (2018) Barry V L Potter JOURNAL OF MOLECULAR ENDOCRINOLOGY
- SULFATION PATHWAYS: A role for steroid sulphatase in intracrine regulation of endometrial decidualisation
- (2018) Douglas A Gibson et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- SULFATION PATHWAYS: Contribution of intracrine oestrogens to the aetiology of endometriosis
- (2018) Carla A Piccinato et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Steroid sulfatase inhibition success and limitation in breast cancer clinical assays: an underlying mechanism
- (2018) Xiaoye Sang et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Synthesis and structure–activity relationships of 2- and/or 4-halogenated 13β- and 13α-estrone derivatives as enzyme inhibitors of estrogen biosynthesis
- (2018) Ildikó Bacsa et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Identification of zebrafish steroid sulfatase and comparative analysis of the enzymatic properties with human steroid sulfatase
- (2018) Katsuhisa Kurogi et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Increased body fat mass and androgen metabolism – A twin study in healthy young women
- (2018) Veera Vihma et al. STEROIDS
- The sulfatase pathway as estrogen supply in endometrial cancer
- (2018) K.M.C. Cornel et al. STEROIDS
- The expression of sex steroid receptors and sex steroid–synthesizing/metabolizing enzymes in metastasized lymph nodes of prostate cancer
- (2018) Yasuhiro Nakamura et al. HUMAN PATHOLOGY
- Synthesis and biological evaluation of fluorinated N -benzoyl and N -phenylacetoyl derivatives of 3-(4-aminophenyl)-coumarin-7- O -sulfamate as steroid sulfatase inhibitors
- (2017) Mateusz Daśko et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Estrogen Activation by Steroid Sulfatase Increases Colorectal Cancer Proliferation via GPER
- (2017) Lorna C Gilligan et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- First Dual Inhibitors of Steroid Sulfatase (STS) and 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1): Designed Multiple Ligands as Novel Potential Therapeutics for Estrogen-Dependent Diseases
- (2017) Mohamed Salah et al. JOURNAL OF MEDICINAL CHEMISTRY
- Uptake and metabolism of sulphated steroids by the blood-brain barrier in the adult male rat
- (2017) M. Zeeshan Qaiser et al. JOURNAL OF NEUROCHEMISTRY
- Increased levels of enzymes involved in local estradiol synthesis in chronic obstructive pulmonary disease
- (2017) G.F.J. Konings et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- mRNA expression of steroidogenic enzymes, steroid hormone receptors and their coregulators in gastric cancer
- (2017) Bartosz Adam Frycz et al. Oncology Letters
- Clinical significance of the estrogen-modifying enzymes steroid sulfatase and estrogen sulfotransferase in epithelial ovarian cancer
- (2017) Felicitas Mungenast et al. Oncology Letters
- Human steroid sulfatase induces Wnt/β-catenin signaling and epithelial-mesenchymal transition by upregulating Twist1 and HIF-1α in human prostate and cervical cancer cells
- (2017) Sangyun Shin et al. Oncotarget
- Estrogen-Related Factors in the Frontal Lobe of Alzheimer’s Disease Patients and Importance of Body Mass Index
- (2017) Naoko Honma et al. Scientific Reports
- A genetic variant withinSTSpreviously associated with inattention in boys with attention deficit hyperactivity disorder is associated with enhanced cognition in healthy adult males
- (2017) Trevor Humby et al. Brain and Behavior
- Polymorphisms of STS gene and SULT2A1 gene and neurosteroid levels in Han Chinese boys with attention-deficit/hyperactivity disorder: an exploratory investigation
- (2017) Liang-Jen Wang et al. Scientific Reports
- Estrogens in Men: Another Layer of Complexity of Estradiol Metabolism in Pulmonary Hypertension
- (2016) Stevan P. Tofovic et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Design, synthesis, and biological evaluation of new arylamide derivatives possessing sulfonate or sulfamate moieties as steroid sulfatase enzyme inhibitors
- (2016) Mohammed I. El-Gamal et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Sulfatase inhibitors for recidivist breast cancer treatment: A chemical review
- (2016) Ramanpreet Shah et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of a sulfamate-based steroid sulfatase inhibitor with intrinsic selective estrogen receptor modulator properties
- (2016) Charles Ouellet et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Steroid sulfatase inhibitor DU-14 protects spatial memory and synaptic plasticity from disruption by amyloid β protein in male rats
- (2016) Xing-Hua Yue et al. HORMONES AND BEHAVIOR
- Steroid Sulfatase Deficiency and Androgen Activation Before and After Puberty
- (2016) Jan Idkowiak et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Inflammatory regulation of steroid sulfatase: A novel mechanism to control estrogen homeostasis and inflammation in chronic liver disease
- (2016) Mengxi Jiang et al. JOURNAL OF HEPATOLOGY
- Effects of steroid hormone on estrogen sulfotransferase and on steroid sulfatase expression in endometriosis tissue and stromal cells
- (2016) Carla A. Piccinato et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Steroid sulfatase is increased in the placentas and whole blood of women with early-onset preeclampsia
- (2016) Amy M. Gratton et al. PLACENTA
- The Role of Steroid Sulfatase as a Prognostic Factor in Patients with Endometrial Cancer
- (2016) Won Moo Lee et al. YONSEI MEDICAL JOURNAL
- Synthesis and steroid sulfatase inhibitory activities of N-phosphorylated 3-(4-aminophenyl)-coumarin-7-O-sulfamates
- (2016) Mateusz Daśko et al. MedChemComm
- The Important Roles of Steroid Sulfatase and Sulfotransferases in Gynecological Diseases
- (2016) Tea Lanišnik Rižner Frontiers in Pharmacology
- Behavioural and Psychiatric Phenotypes in Men and Boys with X-Linked Ichthyosis: Evidence from a Worldwide Online Survey
- (2016) Sohini Chatterjee et al. PLoS One
- Synthesis and Biological Evaluation of Fluorinated 3-Phenylcoumarin-7-O-Sulfamate Derivatives as Steroid Sulfatase Inhibitors
- (2015) Sebastian Demkowicz et al. Chemical Biology & Drug Design
- The Regulation of Steroid Action by Sulfation and Desulfation
- (2015) Jonathan W. Mueller et al. ENDOCRINE REVIEWS
- Steroid sulfatase activity in subcutaneous and visceral adipose tissue: a comparison between pre- and postmenopausal women
- (2015) Hanna Paatela et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- All sex steroids are made intracellularly in peripheral tissues by the mechanisms of intracrinology after menopause
- (2015) Fernand Labrie JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Hepatic Overexpression of Steroid Sulfatase Ameliorates Mouse Models of Obesity and Type 2 Diabetes through Sex-specific Mechanisms
- (2014) Mengxi Jiang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Population Pharmacokinetic Modelling of Irosustat in Postmenopausal Women with Oestrogen-Receptor Positive Breast Cancer Incorporating Non-Linear Red Blood Cell Uptake
- (2014) Zinnia P. Parra-Guillen et al. PHARMACEUTICAL RESEARCH
- Induced Synthesis of Oestrogens by Glia in the Songbird Brain
- (2013) C. J. Saldanha et al. JOURNAL OF NEUROENDOCRINOLOGY
- Placental expression of a novel primate-specific splice variant of sFlt-1 is upregulated in pregnancies complicated by severe early onset pre-eclampsia
- (2011) CL Whitehead et al. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
- Induction of steroid sulfatase expression by tumor necrosis factor-α through phosphatidylinositol 3-kinase/Akt signaling pathway in PC-3 human prostate cancer cells
- (2011) Bo-Young Suh et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Steroid sulfatase is a potential modifier of cognition in attention deficit hyperactivity disorder
- (2011) E. Stergiakouli et al. GENES BRAIN AND BEHAVIOR
- Polymorphisms of the steroid sulfatase (STS) gene are associated with attention deficit hyperactivity disorder and influence brain tissue mRNA expression
- (2010) K.J. Brookes et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Analysis of the STS gene in 40 patients with recessive X-linked ichthyosis: a high frequency of partial deletions in a Spanish population
- (2010) J Cañueto et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion
- (2009) X N Meng et al. BRITISH JOURNAL OF CANCER
- Transcriptional control of human steroid sulfatase
- (2009) Alessia Nardi et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now