Estrogen Activation by Steroid Sulfatase Increases Colorectal Cancer Proliferation via GPER

Epigenetic down regulation of G protein-coupled estrogen receptor (GPER) functions as a tumor suppressor in colorectal cancer

(2017) Qiao Liu et al.   Molecular Cancer

Increased risk of colorectal cancer in patients diagnosed with breast cancer in women

(2016) Yunxia Lu et al.   Cancer Epidemiology

The Regulation of Steroid Action by Sulfation and Desulfation

(2015) Jonathan W. Mueller et al.   ENDOCRINE REVIEWS

Estrogen receptor β expression and colorectal cancer

(2015) Yaron Niv   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Ca2+ channel subunit α 1D promotes proliferation and migration of endometrial cancer cells mediated by 17β-estradiol via the G protein-coupled estrogen receptor

(2015) Juan Hao et al.   FASEB JOURNAL

Estrogen regulates Hippo signaling via GPER in breast cancer

(2015) Xin Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

What have we learned about GPER function in physiology and disease from knockout mice?

(2015) Eric R. Prossnitz et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

G protein-coupled estrogen receptor is involved in modulating colonic motor function via nitric oxide release in C57BL/6 female mice

(2015) Y. Li et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Synergistic control of sex hormones by 17β-HSD type 7: a novel target for estrogen-dependent breast cancer

(2015) Xiaoqiang Wang et al.   Journal of Molecular Cell Biology

Deregulated expression of connective tissue growth factor (CTGF/CCN2)is linked to poor outcome in human cancer

(2014) Julia E. Wells et al.   INTERNATIONAL JOURNAL OF CANCER

Molecular Pathways: Estrogen Pathway in Colorectal Cancer

(2013) A. Barzi et al.   CLINICAL CANCER RESEARCH

Oestrogens promote tumorigenesis in a mouse model for colitis-associated cancer

(2013) Jarom Heijmans et al.   GUT

Oestrogen and colorectal cancer: mechanisms and controversies

(2013) Paul A. Foster   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

G Protein-coupled Estrogen Receptor Mediates the Up-regulation of Fatty Acid Synthase Induced by 17β-Estradiol in Cancer Cells and Cancer-associated Fibroblasts

(2012) Maria Francesca Santolla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The effect of estrogen vs. combined estrogen-progestogen therapy on the risk of colorectal cancer

(2011) Kueiyu Joshua Lin et al.   INTERNATIONAL JOURNAL OF CANCER

Expression of CTGF and Cyr61 in colorectal cancer

(2010) R. Ladwa et al.   JOURNAL OF CLINICAL PATHOLOGY

Postmenopausal Levels of Endogenous Sex Hormones and Risk of Colorectal Cancer

(2009) T. V. Clendenen et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Steroid Sulfatase and Estrogen Sulfotransferase in Colon Carcinoma: Regulators of Intratumoral Estrogen Concentrations and Potent Prognostic Factors

(2009) R. Sato et al.   CANCER RESEARCH

Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF

(2009) Deo Prakash Pandey et al.   EMBO JOURNAL

Transcriptional analysis of estrogen receptor alpha variant mRNAs in colorectal cancers and their matched normal colorectal tissues

(2008) Haiping Jiang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Effects of mutations and glycosylations on STS activity: A site-directed mutagenesis study

(2007) Chloe Stengel et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY