The role of Notch ligand, Delta-like ligand 4 (DLL4), in cancer angiogenesis—implications for therapy
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Title
The role of Notch ligand, Delta-like ligand 4 (DLL4), in cancer angiogenesis—implications for therapy
Authors
Keywords
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Journal
European Surgery-Acta Chirurgica Austriaca
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-04-26
DOI
10.1007/s10353-021-00707-x
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Note: Only part of the references are listed.- Oncolytic HSV infected glioma cells activate NOTCH in adjacent tumor cells sensitizing tumors to gamma secretase inhibition.
- (2020) Yoshihiro Otani et al. CLINICAL CANCER RESEARCH
- Long non-coding RNA UCA1 promotes malignant phenotypes of renal cancer cells by modulating the miR-182-5p/DLL4 axis as a ceRNA
- (2020) Wei Wang et al. Molecular Cancer
- Resistance Mechanisms to Anti-angiogenic Therapies in Cancer
- (2020) Yolla Haibe et al. Frontiers in Oncology
- Quantitative analysis on in vivo tumor-microvascular images from optical-resolution photoacoustic microscopy
- (2019) Qian Zhao et al. Journal of Biophotonics
- The bispecific antibody HB-32, blockade of both VEGF and DLL4 shows potent anti-angiogenic activity in vitro and anti-tumor activity in breast cancer xenograft models
- (2019) Rihong Zhou et al. EXPERIMENTAL CELL RESEARCH
- High levels of Notch intracellular cleaved domain are associated with stemness and reduced bevacizumab efficacy in patients with advanced colon cancer
- (2019) Francesca Negri et al. ONCOLOGY REPORTS
- Tumor angiogenesis: causes, consequences, challenges and opportunities
- (2019) Roberta Lugano et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Contribution of Tumor Endothelial Cells in Cancer Progression
- (2018) Kyoko Hida et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- ABT-165, a Dual Variable Domain Immunoglobulin (DVD-Ig) Targeting DLL4 and VEGF, Demonstrates Superior Efficacy and Favorable Safety Profiles in Preclinical Models
- (2018) Yingchun Li et al. MOLECULAR CANCER THERAPEUTICS
- Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer
- (2018) Monika A. Jarzabek et al. PLoS One
- Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses
- (2018) Fokhrul Hossain et al. Frontiers in Immunology
- An antibody fragment against human delta-like ligand-4 for inhibition of cell proliferation and neovascularization
- (2018) Rasoul Baharlou et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- A first-in-human phase 1a study of the bispecific anti-DLL4/anti-VEGF antibody navicixizumab (OMP-305B83) in patients with previously treated solid tumors
- (2018) Antonio Jimeno et al. INVESTIGATIONAL NEW DRUGS
- Notch and its oncogenic activity in human malignancies
- (2017) Marlena Brzozowa-Zasada et al. European Surgery-Acta Chirurgica Austriaca
- Simultaneous blockade of VEGF and Dll4 by HD105, a bispecific antibody, inhibits tumor progression and angiogenesis
- (2016) Dongheon Lee et al. mAbs
- Notch signalling pathway as an oncogenic factor involved in cancer development
- (2016) Marlena Brzozowa-Zasada et al. Wspolczesna Onkologia-Contemporary Oncology
- Endothelial Jagged1 Antagonizes Dll4 Regulation of Endothelial Branching and Promotes Vascular Maturation Downstream of Dll4/Notch1
- (2015) A.-R. Pedrosa et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Delta-like ligand 4-targeted nanomedicine for antiangiogenic cancer therapy
- (2015) Ya-Rong Liu et al. BIOMATERIALS
- Incomplete Dll4/Notch signaling inhibition promotes functional angiogenesis supporting the growth of skin papillomas
- (2015) Dusan Djokovic et al. BMC CANCER
- The complex interplay between Notch signaling and Snail1 transcription factor in the regulation of epithelial–mesenchymal transition (EMT)
- (2015) M. Brzozowa-Zasada et al. European Surgery-Acta Chirurgica Austriaca
- Correlation of high delta-like ligand 4 expression with peritumoral brain edema and its prediction of poor prognosis in patients with primary high-grade gliomas
- (2015) Xian-xin Qiu et al. JOURNAL OF NEUROSURGERY
- Dose dependent pharmacokinetics, tissue distribution, and anti-tumor efficacy of a humanized monoclonal antibody against DLL4 in mice
- (2014) Amrita V Kamath et al. mAbs
- High Delta-Like Ligand 4 (DLL4) Is Correlated With Peritumoral Brain Edema and Predicts Poor Prognosis in Primary Glioblastoma
- (2014) Xian-xin Qiu et al. MEDICINE
- Delta-like ligand 4: A predictor of poor prognosis in clear cell renal cell carcinoma
- (2014) WEI WANG et al. Oncology Letters
- Down-Regulated miR-30a in Clear Cell Renal Cell Carcinoma Correlated with Tumor Hematogenous Metastasis by Targeting Angiogenesis-Specific DLL4
- (2013) Qing Bo Huang et al. PLoS One
- Role of Notch signaling pathway in gastric cancer pathogenesis
- (2013) Marlena Brzozowa et al. Wspolczesna Onkologia-Contemporary Oncology
- Cross-talk between leukemic and endothelial cells promotes angiogenesis by VEGF activation of the Notch/Dll4 pathway
- (2012) Jingru Zhang et al. CARCINOGENESIS
- Fine-tuning of the intracellular canonical Notch signaling pathway
- (2012) Tilman Borggrefe et al. CELL CYCLE
- DLL4-Notch Signaling Mediates Tumor Resistance to Anti-VEGF Therapy In Vivo
- (2011) J.-L. Li et al. CANCER RESEARCH
- Anti-VEGF and beyond: shaping a new generation of anti-angiogenic therapies for cancer
- (2011) Francesco Bertolini et al. DRUG DISCOVERY TODAY
- Cross-talk between endothelial cells and tumor via delta-like ligand4/Notch/PTEN signaling inhibits lung cancer growth
- (2011) X-Y Ding et al. ONCOGENE
- Expression of Vascular Notch Ligand Delta-Like 4 and Inflammatory Markers in Breast Cancer
- (2010) Adrian M. Jubb et al. AMERICAN JOURNAL OF PATHOLOGY
- Anti-DLL4 Inhibits Growth and Reduces Tumor-Initiating Cell Frequency in Colorectal Tumors with Oncogenic KRAS Mutations
- (2010) M. Fischer et al. CANCER RESEARCH
- Vessel abnormalization: another hallmark of cancer?Molecular mechanisms and therapeutic implications
- (2010) Katrien De Bock et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- VEGF and Delta-Notch: interacting signalling pathways in tumour angiogenesis
- (2008) G Thurston et al. BRITISH JOURNAL OF CANCER
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