Anti-inflammatory activity of ortho-trifluoromethoxy-substituted 4-piperidione-containing mono-carbonyl curcumin derivatives in vitro and in vivo

Recent Developments of Small Molecules with Anti-inflammatory Activities for the Treatment of Acute Lung Injury

(2020) Tianpeng Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The curcumin analog EF24 is a novel senolytic agent

(2019) Wen Li et al.   Aging-US

Monocarbonyl Curcumin-Based Molecular Hybrids as Potent Antibacterial Agents

(2019) Atamjit Singh et al.   ACS Omega

Design, synthesis, anti-lung cancer activity, and chemosensitization of tumor-selective MCACs based on ROS-mediated JNK pathway activation and NF-κB pathway inhibition

(2018) Liping Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Oxidative Stress and Effect of Treatment on the Oxidation Product Decomposition Processes in IBD

(2018) Ewa Dudzińska et al.   Oxidative Medicine and Cellular Longevity

Bioactivities of EF24, a Novel Curcumin Analog: A Review

(2018) Yonghan He et al.   Frontiers in Oncology

Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 2: Current Management

(2017) Marcus Harbord et al.   Journal of Crohns & Colitis

3,5-Bis(2-fluorobenzylidene)-4-piperidone induce reactive oxygen species-mediated apoptosis in A549 cells

(2017) Guo-Yun Liu et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis and optimization of novel allylated mono-carbonyl analogs of curcumin (MACs) act as potent anti-inflammatory agents against LPS-induced acute lung injury (ALI) in rats

(2016) Heping Zhu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2,2′-Fluorine mono-carbonyl curcumin induce reactive oxygen species-Mediated apoptosis in Human lung cancer NCI-H460 cells

(2016) Guo-Yun Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Anti-inflammatory action of high molecular weight Mytilus edulis hydrolysates fraction in LPS-induced RAW264.7 macrophage via NF-κB and MAPK pathways

(2016) Young-Sang Kim et al.   FOOD CHEMISTRY

Anti-inflammatory Actions of (+)-3′α-Angeloxy-4′-keto-3′,4′-dihydroseselin (Pd-Ib) against Dextran Sulfate Sodium-Induced Colitis in C57BL/6 Mice

(2016) Huai-Xue Mu et al.   JOURNAL OF NATURAL PRODUCTS

Fluorination methods in drug discovery

(2016) Damian E. Yerien et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Curcumin Modulates Macrophage Polarization Through the Inhibition of the Toll-Like Receptor 4 Expression and its Signaling Pathways

(2015) Yaoyao Zhou et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Insights into the importance for designing curcumin-inspired anticancer agents by a prooxidant strategy: The case of diarylpentanoids

(2015) Fang Dai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Curcumin, a golden spice with a low bioavailability

(2015) Angelo Siviero et al.   Journal of Herbal Medicine

The Role of Nitric Oxide and Oxidative Stress in Intestinal Damage Induced by Selenium Deficiency in Chickens

(2014) Jiao Yu et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Redox Regulation of Inflammation: Old Elements, a New Story

(2014) Yunlong Lei et al.   MEDICINAL RESEARCH REVIEWS

Conventional drug therapy for inflammatory bowel disease

(2014) Robert V Bryant et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Profound Methyl Effects in Drug Discovery and a Call for New CH Methylation Reactions

(2013) Heike Schönherr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification of Michael Acceptor-Centric Pharmacophores with Substituents That Yield Strong Thioredoxin Reductase Inhibitory Character Correlated to Antiproliferative Activity

(2013) Fei-Fei Gan et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive Oxygen Species in Inflammation and Tissue Injury

(2013) Manish Mittal et al.   ANTIOXIDANTS & REDOX SIGNALING

Discovery and evaluation of piperid-4-one-containing mono-carbonyl analogs of curcumin as anti-inflammatory agents

(2013) Jianzhang Wu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Epidemiology and Natural History of Inflammatory Bowel Diseases

(2011) Jacques Cosnes et al.   GASTROENTEROLOGY

Cinnamaldehydes inhibit thioredoxin reductase and induce Nrf2: potential candidates for cancer therapy and chemoprevention

(2009) Eng-Hui Chew et al.   FREE RADICAL BIOLOGY AND MEDICINE

Exploring the ameliorative potential ofPunica granatumin dextran sulfate sodium induced ulcerative colitis in mice

(2009) Kavinder Singh et al.   PHYTOTHERAPY RESEARCH

Quantitative cellular uptake, localization and cytotoxicity of curcumin in normal and tumor cells

(2008) A. Kunwar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Distinct role of spleen tyrosine kinase in the early phosphorylation of inhibitor of κBα via activation of the phosphoinositide-3-kinase and Akt pathways

(2008) Yong Gyu Lee et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease

(2008) A. N. Begum et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS