The role of inflammatory mediators in epilepsy: Focus on developmental and epileptic encephalopathies and therapeutic implications
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Title
The role of inflammatory mediators in epilepsy: Focus on developmental and epileptic encephalopathies and therapeutic implications
Authors
Keywords
Neuroinflammation, Epilepsy, Cytokine, Chemokine, West syndrome, Steroid
Journal
EPILEPSY RESEARCH
Volume 172, Issue -, Pages 106588
Publisher
Elsevier BV
Online
2021-02-19
DOI
10.1016/j.eplepsyres.2021.106588
References
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Note: Only part of the references are listed.- Clinical evaluation of neuroinflammation in child-onset focal epilepsy: a translocator protein PET study
- (2021) Kuriko Kagitani-Shimono et al. Journal of Neuroinflammation
- Neurocritical care and target immunotherapy for febrile infection-related epilepsy syndrome
- (2020) Hiroshi Sakuma et al. Biomedical Journal
- The ketogenic diet for infants: How long can you go?
- (2020) Anastasia Dressler et al. EPILEPSY RESEARCH
- Neuroinflammation in Children With Infantile Spasms: A Prospective Study Before and After Treatment With Acthar Gel (Repository Corticotropin Injection)
- (2020) Harry T. Chugani et al. JOURNAL OF CHILD NEUROLOGY
- Efficacy and Safety of a Ketogenic Diet in Children and Adolescents with Refractory Epilepsy—A Review
- (2020) Jana Wells et al. Nutrients
- Peripheral blood expression levels of inflammasome complex components in two different focal epilepsy syndromes
- (2020) Canan Ulusoy et al. JOURNAL OF NEUROIMMUNOLOGY
- Efficacy of the ketogenic diet in patients with Dravet syndrome: A meta-analysis
- (2020) Yan-Qiu Wang et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- Rasmussen's encephalitis: From immune pathogenesis towards targeted-therapy
- (2020) A. Orsini et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- Interleukin-10 inhibits interleukin-1β production and inflammasome activation of microglia in epileptic seizures
- (2019) Yi Sun et al. Journal of Neuroinflammation
- Efficacy and tolerability of the ketogenic diet versus high-dose adrenocorticotropic hormone for infantile spasms: A single-center parallel-cohort randomized controlled trial
- (2019) Anastasia Dressler et al. EPILEPSIA
- Significant roles of neuroinflammation in Parkinson’s disease: therapeutic targets for PD prevention
- (2019) Yujeong Lee et al. ARCHIVES OF PHARMACAL RESEARCH
- The Role of Chemokines in the Pathophysiology of Major Depressive Disorder
- (2019) Vladimir M. Milenkovic et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Differential neuro-immune patterns in two clinically relevant murine models of multiple sclerosis
- (2019) Krista D. DiSano et al. Journal of Neuroinflammation
- A New Hose to Extinguish the FIRES?
- (2019) Nicolas Gaspard Epilepsy Currents
- Molecular Mechanism Involved in the Pathogenesis of Early-Onset Epileptic Encephalopathy
- (2019) Giovanna Vitaliti et al. Frontiers in Molecular Neuroscience
- Chemokines in Alzheimer’s Disease: New Insights Into Prokineticins, Chemokine-Like Proteins
- (2019) Anna Rita Zuena et al. Frontiers in Pharmacology
- MiR-206 inhibits epilepsy and seizure-induced brain injury by targeting CCL2
- (2019) Zhenggang Wu et al. CYTOTECHNOLOGY
- Early changes in pro-inflammatory cytokine levels in neonates with encephalopathy are associated with remote epilepsy
- (2019) Adam L. Numis et al. PEDIATRIC RESEARCH
- Utility of chemokines CCL2, CXCL8, 10 and 13 and interleukin 6 in the pediatric cohort for the recognition of neuroinflammation and in the context of traditional cerebrospinal fluid neuroinflammatory biomarkers
- (2019) Zuzana Liba et al. PLoS One
- Centromedian thalamic nuclei deep brain stimulation and Anakinra treatment for FIRES – Two different outcomes
- (2019) Mario Sa et al. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
- Ketogenic diet activates protective γδ T cell responses against influenza virus infection
- (2019) Emily L. Goldberg et al. Science Immunology
- High Mobility Group Box 1 is a novel pathogenic factor and a mechanistic biomarker for epilepsy
- (2018) Teresa Ravizza et al. BRAIN BEHAVIOR AND IMMUNITY
- The epileptic encephalopathy jungle – from Dr West to the concepts of aetiology-related and developmental encephalopathies
- (2018) Judith Kalser et al. CURRENT OPINION IN NEUROLOGY
- Altered vaccine-induced immunity in children with Dravet syndrome
- (2018) Stéphane Auvin et al. EPILEPSIA
- Serial Analysis of Multiple Serum Cytokine Responses to Adrenocorticotropic Hormone Therapy in Patients With West Syndrome
- (2018) Gaku Yamanaka et al. JOURNAL OF CHILD NEUROLOGY
- Review: Neuroinflammatory pathways as treatment targets and biomarker candidates in epilepsy: emerging evidence from preclinical and clinical studies
- (2018) E. A. van Vliet et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- An Inflammation-Centric View of Neurological Disease: Beyond the Neuron
- (2018) Stephen D. Skaper et al. Frontiers in Cellular Neuroscience
- Roles of Microglial and Monocyte Chemokines and Their Receptors in Regulating Alzheimer's Disease-Associated Amyloid-β and Tau Pathologies
- (2018) Joana R. Guedes et al. Frontiers in Neurology
- Tocilizumab treatment for new onset refractory status epilepticus
- (2018) Jin-Sun Jun et al. ANNALS OF NEUROLOGY
- Neuro-Immune Hemostasis: Homeostasis and Diseases in the Central Nervous System
- (2018) Ciro De Luca et al. Frontiers in Cellular Neuroscience
- Reduced steroidogenesis in patients with PCDH19-female limited epilepsy
- (2017) Marina Trivisano et al. EPILEPSIA
- Chemokines as new inflammatory players in the pathogenesis of epilepsy
- (2017) Chiara Cerri et al. EPILEPSY RESEARCH
- Toll-like receptors: Significance, ligands, signaling pathways, and functions in mammals
- (2017) Mallenahally Kusha Vidya et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- Treatment of Epileptic Encephalopathies: Current State of the Art
- (2017) Hiroki Nariai et al. JOURNAL OF CHILD NEUROLOGY
- Chemokine CCL2–CCR2 Signaling Induces Neuronal Cell Death via STAT3 Activation and IL-1β Production after Status Epilepticus
- (2017) Dai-Shi Tian et al. JOURNAL OF NEUROSCIENCE
- Blockade of the IL-1R1/TLR4 pathway mediates disease-modification therapeutic effects in a model of acquired epilepsy
- (2017) Valentina Iori et al. NEUROBIOLOGY OF DISEASE
- Immunotherapeutics in Pediatric Autoimmune Central Nervous System Disease: Agents and Mechanisms
- (2017) Margherita Nosadini et al. Seminars in Pediatric Neurology
- Alteration of plasma cytokines in patients with active epilepsy
- (2016) F. Gao et al. ACTA NEUROLOGICA SCANDINAVICA
- Febrile infection-related epilepsy syndrome treated with anakinra
- (2016) Daniel L. Kenney-Jung et al. ANNALS OF NEUROLOGY
- Autoimmune epilepsy
- (2016) Antonio Greco et al. AUTOIMMUNITY REVIEWS
- Anti-tumor necrosis factor alpha therapy (adalimumab) in Rasmussen's encephalitis: An open pilot study
- (2016) Stanislas Lagarde et al. EPILEPSIA
- The Chemokine CCL2 Mediates the Seizure-enhancing Effects of Systemic Inflammation
- (2016) Chiara Cerri et al. JOURNAL OF NEUROSCIENCE
- Current understanding and neurobiology of epileptic encephalopathies
- (2016) Stéphane Auvin et al. NEUROBIOLOGY OF DISEASE
- Inflammatory mediators in human epilepsy: A systematic review and meta-analysis
- (2016) Evelien E. de Vries et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Comparison of the serum cytokine levels before and after adrenocorticotropic hormone (ACTH) therapy in patients with infantile spasm
- (2016) Esra Türe et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- The complex contribution of chemokines to neuroinflammation: switching from beneficial to detrimental effects
- (2015) Ophélia Le Thuc et al. Annals of the New York Academy of Sciences
- In response: Indications and expectations for neuropsychological assessment in routine epilepsy care: Report of the ILAE Neuropsychology Task Force, Diagnostic Methods Commission, 2013-2017
- (2015) Sarah Wilson et al. EPILEPSIA
- Serum inflammatory mediators correlate with disease activity in electrical status epilepticus in sleep (ESES) syndrome
- (2015) Bart van den Munckhof et al. EPILEPSIA
- Ketogenic diet exhibits anti-inflammatory properties
- (2015) Nina Dupuis et al. EPILEPSIA
- Effectiveness of a hybrid corticosteroid treatment regimen on refractory childhood seizures and a review of other corticosteroid treatments
- (2015) Dewi P. Bakker et al. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
- ACTH controls thymocyte homeostasis independent of glucocorticoids
- (2015) Gergely Talaber et al. FASEB JOURNAL
- Mutations of protocadherin 19 in female epilepsy (PCDH19-FE) lead to allopregnanolone deficiency
- (2015) Chuan Tan et al. HUMAN MOLECULAR GENETICS
- Increased CCL2, CCL3, CCL5, and IL-1β cytokine concentration in piriform cortex, hippocampus, and neocortex after pilocarpine-induced seizures
- (2015) Gabriel M. Arisi et al. Journal of Neuroinflammation
- Unknown
- (2015) Huan Yang et al. MOLECULAR MEDICINE
- Intravenous immunoglobulin in neurology—mode of action and clinical efficacy
- (2015) Jan D. Lünemann et al. Nature Reviews Neurology
- A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy models
- (2015) Melissa J. Benson et al. NEUROBIOLOGY OF DISEASE
- Immediate suppression of seizure clusters by corticosteroids in PCDH19 female epilepsy
- (2015) Norimichi Higurashi et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- Losartan prevents acquired epilepsy via TGF-β signaling suppression
- (2014) Guy Bar-Klein et al. ANNALS OF NEUROLOGY
- Astrocyte transforming growth factor beta 1 promotes inhibitory synapse formation via CaM kinase II signaling
- (2014) Luan Pereira Diniz et al. GLIA
- Role of Inflammatory Mediators in the Pathogenesis of Epilepsy
- (2014) Tadayuki Shimada et al. MEDIATORS OF INFLAMMATION
- Efficacy and Tolerability of Methylprednisolone Pulse Therapy in Childhood Epilepsies Other Than Infantile Spasms
- (2014) Friedrich Ebinger et al. NEUROPEDIATRICS
- Mechanisms of Epileptogenesis in Pediatric Epileptic Syndromes: Rasmussen Encephalitis, Infantile Spasms, and Febrile Infection-related Epilepsy Syndrome (FIRES)
- (2014) Carlos A. Pardo et al. Neurotherapeutics
- Neuroinflammation after intracerebral hemorrhage
- (2014) Eva Mracsko et al. Frontiers in Cellular Neuroscience
- Targeting inflammation as a therapeutic strategy for drug-resistant epilepsies
- (2014) Giovanna Vitaliti et al. Human Vaccines & Immunotherapeutics
- Adrenocorticotropic Hormone for the Treatment of West Syndrome in Children
- (2013) Nicole A Shumiloff et al. ANNALS OF PHARMACOTHERAPY
- Increased metalloprotease activity in the epileptogenic lesion—Lobectomy reduces metalloprotease activity and urokinase-type uPAR circulating levels
- (2013) Thereza Quirico-Santos et al. BRAIN RESEARCH
- Relationship Between the Chemokine Receptor CCR5 and Microglia in Neurological Disorders: Consequences of Targeting CCR5 on Neuroinflammation, Neuronal Death and Regeneration in a Model of Epilepsy
- (2013) Jean-Pierre Louboutin et al. CNS & Neurological Disorders-Drug Targets
- Interictal interleukin-17A levels are elevated and correlate with seizure severity of epilepsy patients
- (2013) Ling-Yan Mao et al. EPILEPSIA
- Fractalkine/CX3CL1 modulates GABAAcurrents in human temporal lobe epilepsy
- (2013) Cristina Roseti et al. EPILEPSIA
- Differential expression of interferon-γ and chemokine genes distinguishes Rasmussen encephalitis from cortical dysplasia and provides evidence for an early Th1 immune response
- (2013) Geoffrey C Owens et al. Journal of Neuroinflammation
- Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain
- (2013) Geeta Ramesh et al. MEDIATORS OF INFLAMMATION
- Neurogenic neuroinflammation: inflammatory CNS reactions in response to neuronal activity
- (2013) Dimitris N. Xanthos et al. NATURE REVIEWS NEUROSCIENCE
- Receptor for Advanced Glycation Endproducts is upregulated in temporal lobe epilepsy and contributes to experimental seizures
- (2013) Valentina Iori et al. NEUROBIOLOGY OF DISEASE
- A Role for the CXCR3/CXCL10 Axis in Rasmussen Encephalitis
- (2013) Isabel Mirones et al. PEDIATRIC NEUROLOGY
- An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies
- (2013) Domenica Musumeci et al. PHARMACOLOGY & THERAPEUTICS
- Febrile infection-related epilepsy syndrome: A study of 12 patients
- (2013) Roberto H. Caraballo et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- Chemokines in CNS injury and repair
- (2012) Anne Jaerve et al. CELL AND TISSUE RESEARCH
- Mechanisms underlying blood-brain barrier dysfunction in brain pathology and epileptogenesis: Role of astroglia
- (2012) Richard Kovács et al. EPILEPSIA
- The Chemokine Superfamily Revisited
- (2012) Albert Zlotnik et al. IMMUNITY
- IL-17 and IL-22 in Cerebrospinal Fluid and Plasma Are Elevated in Guillain-Barré Syndrome
- (2012) Shujuan Li et al. MEDIATORS OF INFLAMMATION
- Immunoglobulin Treatment for Severe Childhood Epilepsy
- (2012) Karen Geva-Dayan et al. PEDIATRIC NEUROLOGY
- Expression of monocyte chemoattractant protein-1 in brain tissue of patients with intractable epilepsy
- (2011) Y. Wu et al. CLINICAL NEUROPATHOLOGY
- Inflammation in epilepsy: Clinical observations
- (2011) Eleonora Aronica et al. EPILEPSIA
- Lumping encephalopathies with inflammation-mediated status epilepticus: Is there enough evidence?
- (2011) Pasquale Striano et al. EPILEPSY & BEHAVIOR
- The serum level of interleukin-6 in patients with intellectual disability and refractory epilepsy
- (2011) Kai A. Lehtimäki et al. EPILEPSY RESEARCH
- Epilepsy and brain inflammation
- (2011) Annamaria Vezzani et al. EXPERIMENTAL NEUROLOGY
- Role of microglia in CNS inflammation
- (2011) Manuel B. Graeber et al. FEBS LETTERS
- Interleukin-1 type 1 receptor/Toll-like receptor signalling in epilepsy: the importance of IL-1beta and high-mobility group box 1
- (2011) M. Maroso et al. JOURNAL OF INTERNAL MEDICINE
- Neurochemokines: a menage a trois providing new insights on the functions of chemokines in the central nervous system
- (2011) William Rostène et al. JOURNAL OF NEUROCHEMISTRY
- Clinical use of CCR5 inhibitors in HIV and beyond
- (2011) Bruce L Gilliam et al. Journal of Translational Medicine
- Inflammation and prevention of epileptogenesis
- (2011) Teresa Ravizza et al. NEUROSCIENCE LETTERS
- Interleukin-1β Biosynthesis Inhibition Reduces Acute Seizures and Drug Resistant Chronic Epileptic Activity in Mice
- (2011) Mattia Maroso et al. Neurotherapeutics
- Is ACTH a key to understanding anticonvulsant action?
- (2010) ME O'Regan et al. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
- Chemokine CCL2 modulation of neuronal excitability and synaptic transmission in rat hippocampal slices
- (2010) Yan Zhou et al. JOURNAL OF NEUROCHEMISTRY
- The emerging role for chemokines in epilepsy
- (2010) Paolo F. Fabene et al. JOURNAL OF NEUROIMMUNOLOGY
- Increased level of serum interleukin-1 receptor antagonist subsequent to resolution of clinical symptoms in patients with West syndrome
- (2010) Gaku Yamanaka et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures
- (2010) Mattia Maroso et al. NATURE MEDICINE
- The role of inflammation in epilepsy
- (2010) Annamaria Vezzani et al. Nature Reviews Neurology
- Methylprednisolone for the Treatment of Children with Refractory Epilepsy
- (2010) R. A. Sevilla-Castillo et al. NEUROPEDIATRICS
- Tissue plasminogen activator and urokinase plasminogen activator in human epileptogenic pathologies
- (2010) A.M. Iyer et al. NEUROSCIENCE
- Fcγ receptors contribute to pyramidal cell death in the mouse hippocampus following local kainic acid injection
- (2010) S. Suemitsu et al. NEUROSCIENCE
- A pilot study on the changes in immunity after ACTH therapy in patients with West syndrome
- (2009) Takashi Ohya et al. BRAIN & DEVELOPMENT
- Peripheral lymphocyte subset and serum cytokine profiles of patients with West syndrome
- (2009) Takashi Shiihara et al. BRAIN & DEVELOPMENT
- Landau-Kleffner syndrome and CSWS syndrome: Treatment with intravenous immunoglobulins
- (2009) Willem F. M. Arts et al. EPILEPSIA
- Corticosteroids as treatment of epileptic syndromes with continuous spike-waves during slow-wave sleep
- (2009) Marga Buzatu et al. EPILEPSIA
- Reduced levels of interleukin-1 receptor antagonist in the cerebrospinal fluid in patients with West syndrome
- (2009) Kazuhiro Haginoya et al. EPILEPSY RESEARCH
- Blood–brain barrier breakdown-inducing astrocytic transformation: Novel targets for the prevention of epilepsy
- (2009) Alon Friedman et al. EPILEPSY RESEARCH
- Contributions of peripheral inflammation to seizure susceptibility: Cytokines and brain excitability
- (2009) Kiarash Riazi et al. EPILEPSY RESEARCH
- Chemokine CCL2 and its receptor CCR2 are increased in the hippocampus following pilocarpine-induced status epilepticus
- (2009) Maira L Foresti et al. Journal of Neuroinflammation
- Cellular injury and neuroinflammation in children with chronic intractable epilepsy
- (2009) Jieun Choi et al. Journal of Neuroinflammation
- Interleukin-6 levels are increased in temporal lobe epilepsy but not in extra-temporal lobe epilepsy
- (2009) Suvi Liimatainen et al. JOURNAL OF NEUROLOGY
- Transcriptome Profiling Reveals TGF- Signaling Involvement in Epileptogenesis
- (2009) L. P. Cacheaux et al. JOURNAL OF NEUROSCIENCE
- Age-dependent vascular changes induced by status epilepticus in rat forebrain: Implications for epileptogenesis
- (2009) Jessica Marcon et al. NEUROBIOLOGY OF DISEASE
- Immune Proteins in Brain Development and Synaptic Plasticity
- (2009) Lisa M. Boulanger NEURON
- Interleukin-17 and Type 17 Helper T Cells
- (2009) Pierre Miossec et al. NEW ENGLAND JOURNAL OF MEDICINE
- A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1
- (2008) S. Balosso et al. BRAIN
- The role of cytokines in the pathophysiology of epilepsy
- (2008) Annamaria Vezzani et al. BRAIN BEHAVIOR AND IMMUNITY
- Possible role of the innate immunity in temporal lobe epilepsy
- (2008) Koen L.I. van Gassen et al. EPILEPSIA
- Efficacy and prognosis of a short course of prednisolone therapy for pediatric epilepsy
- (2008) S.J. You et al. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
- A critical overview of the influence of inflammation and infection on P-glycoprotein expression and activity in the brain
- (2008) Derek J Roberts et al. Expert Opinion on Drug Metabolism & Toxicology
- Chemokines in and out of the central nervous system: much more than chemotaxis and inflammation
- (2008) Astrid E. Cardona et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Interleukin Converting Enzyme inhibition impairs kindling epileptogenesis in rats by blocking astrocytic IL-1β production
- (2008) Teresa Ravizza et al. NEUROBIOLOGY OF DISEASE
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