Mechanisms of signalling-memory governing progression through the eukaryotic cell cycle

Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B

(2020) Nadia Hégarat et al.   EMBO JOURNAL

Restriction point regulation at the crossroads between quiescence and cell proliferation

(2020) Betheney R. Pennycook et al.   FEBS LETTERS

Transient Hysteresis in CDK4/6 Activity Underlies Passage of the Restriction Point in G1

(2019) Mingyu Chung et al.   MOLECULAR CELL

The G2-to-M Transition Is Ensured by a Dual Mechanism that Protects Cyclin B from Degradation by Cdc20-Activated APC/C

(2019) Pablo Lara-Gonzalez et al.   DEVELOPMENTAL CELL

PP2A‐B56 binds to Apc1 and promotes Cdc20 association with the APC/C ubiquitin ligase in mitosis

(2019) Kazuyuki Fujimitsu et al.   EMBO REPORTS

Cyclin A-cdk1-Dependent Phosphorylation of Bora Is the Triggering Factor Promoting Mitotic Entry

(2018) Suzanne Vigneron et al.   DEVELOPMENTAL CELL

A Precise Cdk Activity Threshold Determines Passage through the Restriction Point

(2018) Clayton Schwarz et al.   MOLECULAR CELL

EMI1 switches from being a substrate to an inhibitor of APC/CCDH1 to start the cell cycle

(2018) Steven D. Cappell et al.   NATURE

Control of the Restriction Point by Rb and p21

(2018) Justin Moser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two Interlinked Bistable Switches Govern Mitotic Control in Mammalian Cells

(2018) Scott Rata et al.   CURRENT BIOLOGY

Competing memories of mitogen and p53 signalling control cell-cycle entry

(2017) Hee Won Yang et al.   NATURE

Distinct kinetics of serine and threonine dephosphorylation are essential for mitosis

(2017) Jamin B. Hein et al.   NATURE CELL BIOLOGY

DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression

(2017) Alexis R. Barr et al.   Nature Communications

Quantitative Cell Cycle Analysis Based on an Endogenous All-in-One Reporter for Cell Tracking and Classification

(2017) Thomas Zerjatke et al.   Cell Reports

Endogenous Replication Stress in Mother Cells Leads to Quiescence of Daughter Cells

(2017) Mansi Arora et al.   Cell Reports

Irreversible APC Cdh1 Inactivation Underlies the Point of No Return for Cell-Cycle Entry

(2016) Steven D. Cappell et al.   CELL

Two Bistable Switches Govern M Phase Entry

(2016) Satoru Mochida et al.   CURRENT BIOLOGY

A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit

(2016) Michael J. Cundell et al.   JOURNAL OF CELL BIOLOGY

Molecular mechanism of APC/C activation by mitotic phosphorylation

(2016) Suyang Zhang et al.   NATURE

Cyclin-dependent kinase 1-dependent activation of APC/C ubiquitin ligase

(2016) K. Fujimitsu et al.   SCIENCE

A Dynamical Framework for the All-or-None G1/S Transition

(2016) Alexis R. Barr et al.   Cell Systems

Protein phosphatase 1 is essential for Greatwall inactivation at mitotic exit

(2015) A. Heim et al.   EMBO REPORTS

The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit

(2013) Sabrina L. Spencer et al.   CELL

The Cdk1–APC/C cell cycle oscillator circuit functions as a time-delayed, ultrasensitive switch

(2013) Qiong Yang et al.   NATURE CELL BIOLOGY

Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/C

(2012) Helene Labit et al.   EMBO JOURNAL

Origin of bistability underlying mammalian cell cycle entry

(2011) G. Yao et al.   Molecular Systems Biology

Driving the cell cycle with a minimal CDK control network

(2010) Damien Coudreuse et al.   NATURE

The Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A

(2010) A. Gharbi-Ayachi et al.   SCIENCE

Greatwall Phosphorylates an Inhibitor of Protein Phosphatase 2A That Is Essential for Mitosis

(2010) S. Mochida et al.   SCIENCE

A bistable Rb–E2F switch underlies the restriction point

(2008) Guang Yao et al.   NATURE CELL BIOLOGY