EMI1 switches from being a substrate to an inhibitor of APC/CCDH1 to start the cell cycle

Competing memories of mitogen and p53 signalling control cell-cycle entry

(2017) Hee Won Yang et al.   NATURE

Endogenous Replication Stress in Mother Cells Leads to Quiescence of Daughter Cells

(2017) Mansi Arora et al.   Cell Reports

Irreversible APC Cdh1 Inactivation Underlies the Point of No Return for Cell-Cycle Entry

(2016) Steven D. Cappell et al.   CELL

APC/C and SCF cyclin F Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry

(2016) Rajarshi Choudhury et al.   Cell Reports

Enhanced Protein Degradation by Branched Ubiquitin Chains

(2014) Hermann-Josef Meyer et al.   CELL

Molecular architecture and mechanism of the anaphase-promoting complex

(2014) Leifu Chang et al.   NATURE

The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit

(2013) Sabrina L. Spencer et al.   CELL

Emi1 preferentially inhibits ubiquitin chain elongation by the anaphase-promoting complex

(2013) Weiping Wang et al.   NATURE CELL BIOLOGY

Electron microscopy structure of human APC/CCDH1–EMI1 reveals multimodal mechanism of E3 ligase shutdown

(2013) Jeremiah J Frye et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SCF-Mediated Cdh1 Degradation Defines a Negative Feedback System that Coordinates Cell-Cycle Progression

(2013) Hidefumi Fukushima et al.   Cell Reports

Bistability, Bifurcations, and Waddington's Epigenetic Landscape

(2012) James E. Ferrell   CURRENT BIOLOGY

APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

(2012) Nevena V. Dimova et al.   NATURE CELL BIOLOGY

Regulation of the Action of Early Mitotic Inhibitor 1 on the Anaphase-promoting Complex/Cyclosome by Cyclin-dependent Kinases

(2011) Yakir Moshe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deubiquitinase USP37 Is Activated by CDK2 to Antagonize APCCDH1 and Promote S Phase Entry

(2011) XiaoDong Huang et al.   MOLECULAR CELL

Pharmacologic Inhibition of the Anaphase-Promoting Complex Induces A Spindle Checkpoint-Dependent Mitotic Arrest in the Absence of Spindle Damage

(2010) Xing Zeng et al.   CANCER CELL

Regulated Degradation of Spindle Assembly Factors by the Anaphase-Promoting Complex

(2010) Ling Song et al.   MOLECULAR CELL

Detection of sequential polyubiquitylation on a millisecond timescale

(2009) Nathan W. Pierce et al.   NATURE