Granulocyte-macrophage colony-stimulating factor mRNA and Neuroprotective Immunity in Parkinson's disease

Impact of mRNA chemistry and manufacturing process on innate immune activation

(2020) Jennifer Nelson et al.   Science Advances

Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery

(2019) Piotr S. Kowalski et al.   MOLECULAR THERAPY

A Synthetic Agonist to Vasoactive Intestinal Peptide Receptor-2 Induces Regulatory T Cell Neuroprotective Activities in Models of Parkinson’s Disease

(2019) R. Lee Mosley et al.   Frontiers in Cellular Neuroscience

Granulocyte-macrophage colony-stimulating factor neuroprotective activities in Alzheimer’s disease mice

(2018) Tomomi Kiyota et al.   JOURNAL OF NEUROIMMUNOLOGY

Tolerogenic bone marrow-derived dendritic cells induce neuroprotective regulatory T cells in a model of Parkinson’s disease

(2018) Charles R. Schutt et al.   Molecular Neurodegeneration

A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates

(2018) Staci Sabnis et al.   MOLECULAR THERAPY

Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR

(2018) David Zemmour et al.   NATURE IMMUNOLOGY

Alpha-synuclein: Pathology, mitochondrial dysfunction and neuroinflammation in Parkinson’s disease

(2018) Emily M. Rocha et al.   NEUROBIOLOGY OF DISEASE

Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease

(2018) Géraldine Gelders et al.   Journal of Immunology Research

GM-CSF therapy inhibits chronic graft-versus-host disease via expansion of regulatory T cells

(2018) Masaaki Hotta et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery

(2018) Minako Ito et al.   NATURE

Editorial: Axonopathy in Neurodegenerative Disease

(2018) Robert W. Burgess et al.   Frontiers in Neuroscience

T cells and Parkinson's disease

(2017) R Lee Mosley et al.   LANCET NEUROLOGY

Epothilone B impairs functional recovery after spinal cord injury by increasing secretion of macrophage colony-stimulating factor

(2017) Liang Mao et al.   Cell Death & Disease

Parkinson's disease: Autoimmunity and neuroinflammation

(2016) Armando De Virgilio et al.   AUTOIMMUNITY REVIEWS

Immunomodulation as a neuroprotective and therapeutic strategy for Parkinson's disease

(2016) Katherine E Olson et al.   CURRENT OPINION IN PHARMACOLOGY

Amphiregulin Confers Regulatory T Cell Suppressive Function and Tumor Invasion via the EGFR/GSK-3β/Foxp3 Axis

(2016) Sihua Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol Pretreatment Protected against Cerebral Ischemia/Reperfusion Injury in Rats via Expansion of T Regulatory Cells

(2016) HongNa Yang et al.   Journal of Stroke & Cerebrovascular Diseases

Neuroprotective effects of CD4+CD25+Foxp3+ regulatory T cells in a 3xTg-AD Alzheimer’s disease model

(2016) Hyunjung Baek et al.   Oncotarget

Resveratrol Pretreatment Protected against Cerebral Ischemia/Reperfusion Injury in Rats via Expansion of T Regulatory Cells

(2016) HongNa Yang et al.   Journal of Stroke & Cerebrovascular Diseases

IL-33 Receptor-Expressing Regulatory T Cells Are Highly Activated, Th2 Biased and Suppress CD4 T Cell Proliferation through IL-10 and TGFβ Release

(2016) Julia Siede et al.   PLoS One

Neuroinflammation in Parkinson's disease: role in neurodegeneration and tissue repair

(2015) Sayinthen Vivekanantham et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

A Perspective on Roles Played by Innate and Adaptive Immunity in the Pathobiology of Neurodegenerative Disorders

(2015) Howard E. Gendelman et al.   Journal of Neuroimmune Pharmacology

Granulocyte-Macrophage Colony Stimulating Factor Exerts Protective and Immunomodulatory Effects in Cortical Trauma

(2015) Matthew L. Kelso et al.   JOURNAL OF NEUROIMMUNOLOGY

Selective VIP Receptor Agonists Facilitate Immune Transformation for Dopaminergic Neuroprotection in MPTP-Intoxicated Mice

(2015) K. E. Olson et al.   JOURNAL OF NEUROSCIENCE

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed

(2014) Jonathan D Cherry et al.   Journal of Neuroinflammation

Innate and adaptive immune responses in neurodegeneration and repair

(2013) Sandra Amor et al.   IMMUNOLOGY

GM-CSF induces neuroprotective and anti-inflammatory responses in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxicated mice

(2013) Lisa M. Kosloski et al.   JOURNAL OF NEUROIMMUNOLOGY

The innate and adaptive immunological aspects in neurodegenerative diseases

(2013) Maria C.O. Rodrigues et al.   JOURNAL OF NEUROIMMUNOLOGY

Boosting Regulatory T Cells Limits Neuroinflammation in Permanent Cortical Stroke

(2013) A. Liesz et al.   JOURNAL OF NEUROSCIENCE

Adoptive Regulatory T-Cell Therapy Preserves Systemic Immune Homeostasis After Cerebral Ischemia

(2013) Peiying Li et al.   STROKE

Inflammation and Adaptive Immunity in Parkinson's Disease

(2013) R. L. Mosley et al.   Cold Spring Harbor Perspectives in Medicine

GM-CSF promotes inflammatory dendritic cell formation but does not contribute to disease progression in experimental autoimmune myocarditis

(2012) Przemyslaw Blyszczuk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survival

(2012) Jenny S. Henkel et al.   EMBO Molecular Medicine

CD4+ Regulatory and Effector/Memory T Cell Subsets Profile Motor Dysfunction in Parkinson’s Disease

(2012) Jessica A. Hutter Saunders et al.   Journal of Neuroimmune Pharmacology

Molecular Mechanisms of Treg-Mediated T Cell Suppression

(2012) Angelika Schmidt et al.   Frontiers in Immunology

Inflammation-associated S100 proteins: new mechanisms that regulate function

(2010) Jesse Goyette et al.   AMINO ACIDS

T cells in multiple sclerosis and experimental autoimmune encephalomyelitis

(2010) J. M. Fletcher et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Regulatory T cells exhibit enhanced migratory characteristics, a feature impaired in patients with multiple sclerosis

(2010) Tilman Schneider-Hohendorf et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory T Cells Attenuate Th17 Cell-Mediated Nigrostriatal Dopaminergic Neurodegeneration in a Model of Parkinson’s Disease

(2010) Ashley D. Reynolds et al.   JOURNAL OF IMMUNOLOGY

Brain ingress of regulatory T cells in a murine model of HIV-1 encephalitis☆

(2010) Nan Gong et al.   JOURNAL OF NEUROIMMUNOLOGY

The transcription cofactor Hopx is required for regulatory T cell function in dendritic cell–mediated peripheral T cell unresponsiveness

(2010) Daniel Hawiger et al.   NATURE IMMUNOLOGY

Innate and Adaptive Immunity for the Pathobiology of Parkinson's Disease

(2009) David K. Stone et al.   ANTIOXIDANTS & REDOX SIGNALING

A Central Role for Induced Regulatory T Cells in Tolerance Induction in Experimental Colitis

(2009) D. Haribhai et al.   JOURNAL OF IMMUNOLOGY

CD 4+ T cells in the pathobiology of neurodegenerative disorders

(2009) Xiuyan Huang et al.   JOURNAL OF NEUROIMMUNOLOGY

The scientific and clinical basis for the treatment of Parkinson disease (2009)

(2009) C. W. Olanow et al.   NEUROLOGY

IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells

(2009) W. Elyaman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GARP (LRRC32) is essential for the surface expression of latent TGF-  on platelets and activated FOXP3+ regulatory T cells

(2009) D. Q. Tran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory T cells induced by GM-CSF suppress ongoing experimental myasthenia gravis

(2008) Jian Rong Sheng et al.   CLINICAL IMMUNOLOGY

Targeted Overexpression of Human α-Synuclein Triggers Microglial Activation and an Adaptive Immune Response in a Mouse Model of Parkinson Disease

(2008) Shaji Theodore et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Adaptive Immune Neuroprotection in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice

(2008) Rebecca Banerjee et al.   PLoS One