GM-CSF therapy inhibits chronic graft-versus-host disease via expansion of regulatory T cells

Low-dose interleukin-2 as a modulator of Treg homeostasis after HSCT: current understanding and future perspectives

(2017) Ken-ichi Matsuoka   INTERNATIONAL JOURNAL OF HEMATOLOGY

Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease

(2016) John Koreth et al.   BLOOD

Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling

(2016) Sophie E. Broughton et al.   STRUCTURE

Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

(2015) C. G. Brunstein et al.   BLOOD

CSF-1–dependant donor-derived macrophages mediate chronic graft-versus-host disease

(2014) Kylie A. Alexander et al.   JOURNAL OF CLINICAL INVESTIGATION

CD8+CD205+ Splenic Dendritic Cells Are Specialized to Induce Foxp3+ Regulatory T Cells

(2014) S. Yamazaki et al.   JOURNAL OF IMMUNOLOGY

CD1dhiCD5+B Cells Expanded by GM-CSF In Vivo Suppress Experimental Autoimmune Myasthenia Gravis

(2014) Jian Rong Sheng et al.   JOURNAL OF IMMUNOLOGY

CCL22-Producing CD8 - Myeloid Dendritic Cells Mediate Regulatory T Cell Recruitment in Response to G-CSF Treatment

(2013) E. Layseca-Espinosa et al.   JOURNAL OF IMMUNOLOGY

OX40L/Jagged1 Cosignaling by GM-CSF-Induced Bone Marrow-Derived Dendritic Cells Is Required for the Expansion of Functional Regulatory T Cells

(2013) A. Gopisetty et al.   JOURNAL OF IMMUNOLOGY

Induced CD4+Foxp3+ Regulatory T Cells in Immune Tolerance

(2012) Angelina M. Bilate et al.   Annual Review of Immunology

Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets

(2012) K. A. Markey et al.   BLOOD

Regulation of dendritic cell development by GM-CSF: molecular control and implications for immune homeostasis and therapy

(2012) L. van de Laar et al.   BLOOD

GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells

(2012) Melanie Greter et al.   IMMUNITY

The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling

(2012) Sophie E. Broughton et al.   IMMUNOLOGICAL REVIEWS

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

(2011) M. Di Ianni et al.   BLOOD

Immunologic unresponsiveness to alloantigen in vivo: a role for regulatory T cells

(2011) Kathryn J. Wood et al.   IMMUNOLOGICAL REVIEWS

Differentiation of Inflammatory Dendritic Cells Is Mediated by NF- B1-Dependent GM-CSF Production in CD4 T Cells

(2011) I. K. Campbell et al.   JOURNAL OF IMMUNOLOGY

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease

(2011) John Koreth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cellular therapies supplement: the role of granulocyte macrophage colony-stimulating factor and dendritic cells in regulatory T-cell homeostasis and expansion

(2011) Tao Zou et al.   TRANSFUSION

Origin and development of dendritic cells

(2010) Kang Liu et al.   IMMUNOLOGICAL REVIEWS

Dendritic Cells Induce Regulatory T Cell Proliferation through Antigen-Dependent and -Independent Interactions

(2010) T. Zou et al.   JOURNAL OF IMMUNOLOGY

Expansion of peripheral naturally occurring T regulatory cells by Fms-like tyrosine kinase 3 ligand treatment

(2009) L. K. Swee et al.   BLOOD

Dendritic cell homeostasis

(2009) M. Merad et al.   BLOOD

Modulation of dendritic cells using granulocyte-macrophage colony-stimulating factor (GM-CSF) delays type 1 diabetes by enhancing CD4+CD25+ regulatory T cell function

(2009) Donald Cheatem et al.   CLINICAL IMMUNOLOGY

GM-CSF-induced CD11c+CD8a--dendritic cells facilitate Foxp3+ and IL-10+ regulatory T cell expansion resulting in suppression of autoimmune thyroiditis

(2009) B. B. Ganesh et al.   INTERNATIONAL IMMUNOLOGY

In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

(2009) Kylie E. Webster et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

(2009) Guillaume Darrasse-Jèze et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hematopoietic cytokines

(2008) D. Metcalf   BLOOD

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology