Neuroinflammation in Parkinson's disease: role in neurodegeneration and tissue repair

Identification of blood serum micro-RNAs associated with idiopathic andLRRK2Parkinson's disease

(2014) Teresa Botta-Orfila et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression

(2013) Peter Reinhardt et al.   Cell Stem Cell

Activation of microglia induces symptoms of Parkinson’s disease in wild-type, but not in IL-1 knockout mice

(2013) Sachiko Tanaka et al.   Journal of Neuroinflammation

Inflammation and Adaptive Immunity in Parkinson's Disease

(2013) R. L. Mosley et al.   Cold Spring Harbor Perspectives in Medicine

Anti-inflammatory properties rather than anti-oxidant capability is the major mechanism of neuroprotection by sodium salicylate in a chronic rotenone model of Parkinson’s disease

(2012) P. Thakur et al.   NEUROSCIENCE

Meloxicam ameliorates motor dysfunction and dopaminergic neurodegeneration by maintaining Akt-signaling in a mouse Parkinson's disease model

(2012) Yoshikazu Tasaki et al.   NEUROSCIENCE LETTERS

Lipopolysaccharide-induced nigral inflammation leads to increased IL-1β tissue content and expression of astrocytic glial cell line-derived neurotrophic factor

(2012) Mahmoud M. Iravani et al.   NEUROSCIENCE LETTERS

Non-Motor Symptoms in Patients with Parkinson’s Disease – Correlations with Inflammatory Cytokines in Serum

(2012) Daniel Lindqvist et al.   PLoS One

Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson’s Disease

(2011) Hui-Ming Gao et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Genome-wide association study confirms extant PD risk loci among the Dutch

(2011) Javier Simón-Sánchez et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

NSAID use and risk of Parkinson disease: a population-based case-control study

(2011) C. Becker et al.   EUROPEAN JOURNAL OF NEUROLOGY

Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures

(2011) Mansoureh Hakimi et al.   JOURNAL OF NEURAL TRANSMISSION

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

(2011)   LANCET

The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease

(2011) Zhihua Liu et al.   NATURE IMMUNOLOGY

Amantadine protects dopamine neurons by a dual action: Reducing activation of microglia and inducing expression of GNDF in astroglia

(2011) Bernardino Ossola et al.   NEUROPHARMACOLOGY

Human leukocyte antigen variation and Parkinson’s disease

(2011) Andreas Puschmann et al.   PARKINSONISM & RELATED DISORDERS

What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease

(2011) Olga Corti et al.   PHYSIOLOGICAL REVIEWS

Lipopolysaccharide and Tumor Necrosis Factor Regulate Parkin Expression via Nuclear Factor-Kappa B

(2011) Thi A. Tran et al.   PLoS One

Regulatory T Cells Attenuate Th17 Cell-Mediated Nigrostriatal Dopaminergic Neurodegeneration in a Model of Parkinson’s Disease

(2010) Ashley D. Reynolds et al.   JOURNAL OF IMMUNOLOGY

Association of the human leucocyte antigen region with susceptibility to Parkinson's disease

(2010) M. Saiki et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Mitochondrial dysfunction: A potential link between neuroinflammation and neurodegeneration?

(2010) Maarten E. Witte et al.   MITOCHONDRION

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

(2010) Taye H Hamza et al.   NATURE GENETICS

Innate and Adaptive Immunity for the Pathobiology of Parkinson's Disease

(2009) David K. Stone et al.   ANTIOXIDANTS & REDOX SIGNALING

A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

(2009) Kaoru Saijo et al.   CELL

NSAID Use and the Risk of Parkinsonʼs Disease

(2009) Ali Samii et al.   DRUGS & AGING

Nitrated  -Synuclein-Induced Alterations in Microglial Immunity Are Regulated by CD4+ T Cell Subsets

(2009) A. D. Reynolds et al.   JOURNAL OF IMMUNOLOGY

CNS Infiltration of Peripheral Immune Cells: D-Day for Neurodegenerative Disease?

(2009) Kavon Rezai-Zadeh et al.   Journal of Neuroimmune Pharmacology

Neuroinflammation in Parkinson’s Disease

(2009) Jae-Kyung Lee et al.   Journal of Neuroimmune Pharmacology

Human neuromelanin induces neuroinflammation and neurodegeneration in the rat substantia nigra: implications for Parkinson's disease

(2008) Luigi Zecca et al.   ACTA NEUROPATHOLOGICA

Neuroinflammation and Oxidation/Nitration of  -Synuclein Linked to Dopaminergic Neurodegeneration

(2008) H.-M. Gao et al.   JOURNAL OF NEUROSCIENCE

Human Interleukin-10 Gene Transfer Is Protective in a Rat Model of Parkinson's Disease

(2008) Louisa C Johnston et al.   MOLECULAR THERAPY

Glial reactions in Parkinson's disease

(2007) Patrick L. McGeer et al.   MOVEMENT DISORDERS

Synuclein activates microglia in a model of Parkinson's disease

(2007) Xiaomin Su et al.   NEUROBIOLOGY OF AGING

α-Synuclein activates stress signaling protein kinases in THP-1 cells and microglia

(2006) Andis Klegeris et al.   NEUROBIOLOGY OF AGING