HDAC8, A Potential Therapeutic Target for the Treatment of Malignant Peripheral Nerve Sheath Tumors (MPNST)

Anti-Cancer Effect of Thiacremonone through Down Regulation of Peroxiredoxin 6

(2014) Miran Jo et al.   PLoS One

HDAC8 substrates: Histones and beyond

(2012) Noah A. Wolfson et al.   BIOPOLYMERS

Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth

(2012) Taro Hitosugi et al.   CANCER CELL

HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle

(2012) Matthew A. Deardorff et al.   NATURE

Comprehensive identification of novel post-translational modifications in cellular peroxiredoxin 6

(2012) Jaeho Jeong et al.   PROTEOMICS

Acetylation of Heat Shock Protein 20 (Hsp20) Regulates Human Myometrial Activity

(2011) Magdalena Karolczak-Bayatti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Glycolytic Enzyme Phosphoglycerate Mutase-1 by Sirt1 Protein-mediated Deacetylation

(2011) William C. Hallows et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cohesin: a catenase with separate entry and exit gates?

(2011) Kim Nasmyth   NATURE CELL BIOLOGY

High-mobility group box 1 and cancer

(2010) Daolin Tang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Autophagic Survival in Resistance to Histone Deacetylase Inhibitors: Novel Strategies to Treat Malignant Peripheral Nerve Sheath Tumors

(2010) G. Lopez et al.   CANCER RESEARCH

An Acetylation Switch Modulates the Transcriptional Activity of Estrogen-Related Receptor α

(2010) Brian J. Wilson et al.   MOLECULAR ENDOCRINOLOGY

Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease

(2010) James E. Bradner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combining PCI-24781, a Novel Histone Deacetylase Inhibitor, with Chemotherapy for the Treatment of Soft Tissue Sarcoma

(2009) G. Lopez et al.   CLINICAL CANCER RESEARCH

Targeting of HDAC8 and investigational inhibitors in neuroblastoma

(2009) Ina Oehme et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumours

(2009) Subbaya Subramanian et al.   JOURNAL OF PATHOLOGY

Dual targeting of AKT and mammalian target of rapamycin: A potential therapeutic approach for malignant peripheral nerve sheath tumor

(2009) C. Y. Zou et al.   MOLECULAR CANCER THERAPEUTICS

DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses

(2009) S. Vasseur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inactivation of CREB mediated gene transcription by HDAC8 bound protein phosphatase

(2008) Jingxia Gao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Histone Deacetylase 8 in Neuroblastoma Tumorigenesis

(2008) I. Oehme et al.   CLINICAL CANCER RESEARCH

A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas

(2008) S Balasubramanian et al.   LEUKEMIA

Acetylation of Smc3 by Eco1 Is Required for S Phase Sister Chromatid Cohesion in Both Human and Yeast

(2008) Jinglan Zhang et al.   MOLECULAR CELL

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(2008) John Klune et al.   MOLECULAR MEDICINE