Synthesis, characterization, biological evaluation, and in silico studies of novel 1,3‐diaryltriazene‐substituted sulfathiazole derivatives

Sulphonamides incorporating 1,3,5-triazine structural motifs show antioxidant, acetylcholinesterase, butyrylcholinesterase, and tyrosinase inhibitory profile

(2020) Nabih Lolak et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

High Stability of Immobilized Acetylcholinesterase on Chitosan Beads

(2020) Mesut Işık   ChemistrySelect

Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs

(2020) Nebih Lolak et al.   BIOORGANIC CHEMISTRY

Synthesis, crystal structure, and biological evaluation of optically active 2-amino-4-aryl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H -chromen-3-carbonitriles: Antiepileptic, antidiabetic, and anticholinergics potentials

(2019) Abel Maharramov et al.   ARCHIV DER PHARMAZIE

Phytochemical content, antioxidant activity, and enzyme inhibition effect of Salvia eriophora Boiss. & Kotschy against acetylcholinesterase, α-amylase, butyrylcholinesterase, and α-glycosidase enzymes

(2019) Ercan Bursal et al.   JOURNAL OF FOOD BIOCHEMISTRY

Investigation of Potential Paraoxonase-I Inhibitors by Kinetic and Molecular Docking Studies: Chemotherapeutic Drugs

(2019) Cüneyt Türkeş   PROTEIN AND PEPTIDE LETTERS

Synthesis and investigation of anticancer, antibacterial activities and carbonic anhydrase, acetylcholinesterase inhibition profiles of novel (3aR,4S,7R,7aS)-2-[4-[1-acetyl-5-(aryl/heteroaryl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl]-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-diones

(2019) Umit M. Kocyigit et al.   MONATSHEFTE FUR CHEMIE

Towards more effective acetylcholinesterase inhibitors: a comprehensive modelling study based on human acetylcholinesterase protein–drug complex

(2019) Abdulilah Ece   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

The antidiabetic and anticholinergic effects of chrysin on cyclophosphamide-induced multiple organ toxicity in rats: Pharmacological evaluation of some metabolic enzyme activities

(2019) Parham Taslimi et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Anti-diabetic Properties of Calcium Channel Blockers: Inhibition Effects on Aldose Reductase Enzyme Activity

(2019) Cüneyt Türkeş et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Synthesis, characterization, molecular docking and biological activities of novel pyrazoline derivatives

(2019) Fikret Turkan et al.   ARCHIV DER PHARMAZIE

Synthesis and biological evaluation of bromophenol derivatives with cyclopropyl moiety: Ring opening of cyclopropane with monoester

(2019) Murat Boztas et al.   BIOORGANIC CHEMISTRY

Inhibition of Human Serum Paraoxonase-I with Antimycotic Drugs: In Vitro and In Silico Studies

(2019) Cüneyt Türkeş et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Novel eugenol bearing oxypropanolamines: Synthesis, characterization, antibacterial, antidiabetic, and anticholinergic potentials

(2019) Hayriye Genç Bilgiçli et al.   BIOORGANIC CHEMISTRY

Gadolinium-based contrast agents: in vitro paraoxonase 1 inhibition, in silico studies

(2019) Şükrü Beydemir et al.   DRUG AND CHEMICAL TOXICOLOGY

A potential risk factor for paraoxonase 1: in silico and in‐vitro analysis of the biological activity of proton‐pump inhibitors

(2019) Cüneyt Türkeş   JOURNAL OF PHARMACY AND PHARMACOLOGY

Synthesis, biological evaluation and in silico studies of novel N-substituted phthalazine sulfonamide compounds as potent carbonic anhydrase and acetylcholinesterase inhibitors

(2019) Cüneyt Türkeş et al.   BIOORGANIC CHEMISTRY

Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery

(2019) Alessio Nocentini et al.   Expert Opinion on Drug Discovery

Inhibition profiles of Voriconazole against acetylcholinesterase, α‐glycosidase, and human carbonic anhydrase I and II isoenzymes

(2019) Fevzi Topal   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

The Binding Mechanisms and Inhibitory Effect of Intravenous Anesthetics on AChE In Vitro and In Vivo: Kinetic Analysis and Molecular Docking

(2019) Mesut Işık   NEUROCHEMICAL RESEARCH

In Vitro and In Silico Studies on the Toxic Effects of Antibacterial Drugs as Human Serum Paraoxonase 1 Inhibitor

(2019) Cüneyt Türkeş et al.   ChemistrySelect

Novel 2-aminopyridine liganded Pd(II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties

(2019) Fatoş Erdemir et al.   BIOORGANIC CHEMISTRY

Benzenesulfonamide derivatives containing imine and amine groups: Inhibition on human paraoxonase and molecular docking studies

(2019) Mesut Işık et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Novel sulphonamides incorporating triazene moieties show powerful carbonic anhydrase I and II inhibitory properties

(2019) Sinan Bilginer et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Novel carvacrol based new oxypropanolamine derivatives: Design, synthesis, characterization, biological evaluation, and molecular docking studies

(2019) Arlinda Bytyqi-Damoni et al.   JOURNAL OF MOLECULAR STRUCTURE

New Isoindole‐1,3‐dione Substituted Sulfonamides as Potent Inhibitors of Carbonic Anhydrase and Acetylcholinesterase: Design, Synthesis, and Biological Evaluation

(2019) Saliha Gündoğdu et al.   ChemistrySelect

Synthesis and biological evaluation of novel N , N ′-diaryl cyanoguanidines acting as potent and selective carbonic anhydrase II inhibitors

(2018) Suleyman Akocak et al.   BIOORGANIC CHEMISTRY

Design and synthesis of novel 1,3-diaryltriazene-substituted sulfonamides as potent and selective carbonic anhydrase II inhibitors

(2018) Nabih Lolak et al.   BIOORGANIC CHEMISTRY

Experimental and theoretical studies on tautomeric structures of a newly synthesized 2,2′(hydrazine-1,2-diylidenebis(propan-1-yl-1-ylidene))diphenol

(2018) Tuncay Karakurt et al.   CHEMICAL PHYSICS LETTERS

Discovery of 4-Hydroxy-3-(3-(phenylureido)benzenesulfonamides as SLC-0111 Analogues for the Treatment of Hypoxic Tumors Overexpressing Carbonic Anhydrase IX

(2018) Murat Bozdag et al.   JOURNAL OF MEDICINAL CHEMISTRY

The effects of some antibiotics from cephalosporin groups on the acetylcholinesterase and butyrylcholinesterase enzymes activities in different tissues of rats

(2018) Fikret Türkan et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Schiff bases and their amines: Synthesis and discovery of carbonic anhydrase and acetylcholinesterase enzymes inhibitors

(2018) Beyhan Yiğit et al.   ARCHIV DER PHARMAZIE

Synthesis, characterization, and SAR of arylated indenoquinoline-based cholinesterase and carbonic anhydrase inhibitors

(2018) Makbule Ekiz et al.   ARCHIV DER PHARMAZIE

Novel sulfamate derivatives of menthol: Synthesis, characterization, and cholinesterases and carbonic anhydrase enzymes inhibition properties

(2018) Shahla Daryadel et al.   ARCHIV DER PHARMAZIE

Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors – Their antidiabetic, anticholinergic and antibacterial potentials

(2018) Mustafa Zengin et al.   BIOORGANIC CHEMISTRY

Diarylmethanon, bromophenol and diarylmethane compounds: Discovery of potent aldose reductase, α-amylase and α-glycosidase inhibitors as new therapeutic approach in diabetes and functional hyperglycemia

(2018) Parham Taslimi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Antidiabetic and antiparasitic potentials: Inhibition effects of some natural antioxidant compounds on α-glycosidase, α-amylase and human glutathione S-transferase enzymes

(2018) İlhami Gulçin et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The Impacts of Some Sedative Drugs on α-Glycosidase, Acetylcholinesterase and Butyrylcholinesterase Enzymes-Potential Drugs for Some Metabolic Diseases

(2018) Ruya Kaya et al.   Letters in Drug Design & Discovery

Synthesis, characterization, crystal structure, electrochemical studies and biological evaluation of metal complexes with thiosemicarbazone of glyoxylic acid

(2018) Mansura Huseynova et al.   POLYHEDRON

Screening the in vitro antioxidant, antimicrobial, anticholinesterase, antidiabetic activities of endemic Achillea cucullata (Asteraceae) ethanol extract

(2018) N. Eruygur et al.   SOUTH AFRICAN JOURNAL OF BOTANY

Antidiabetic potential: In vitro inhibition effects of bromophenol and diarylmethanones derivatives on metabolic enzymes

(2018) Yeliz Demir et al.   ARCHIV DER PHARMAZIE

In vitro cytotoxic and in vivo antitumoral activities of some aminomethyl derivatives of 2,4-dihydro-3H-1,2,4-triazole-3-thiones-Evaluation of their acetylcholinesterase and carbonic anhydrase enzymes inhibition profiles

(2018) İrfan Timur et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Synthesis and cytotoxic activities of novel copper and silver complexes of 1,3-diaryltriazene-substituted sulfonamides

(2018) Dilek Canakci et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

The effects of hesperidin on sodium arsenite-induced different organ toxicity in rats on metabolic enzymes as antidiabetic and anticholinergics potentials: A biochemical approach

(2018) Cuneyt Caglayan et al.   JOURNAL OF FOOD BIOCHEMISTRY

Imidazolinium chloride salts bearing wingtip groups: Synthesis, molecular docking and metabolic enzymes inhibition

(2018) Beyhan Yiğit et al.   JOURNAL OF MOLECULAR STRUCTURE

Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors

(2018) Zhi-Qiang Cheng et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization, crystal structure of novel bis-thiomethylcyclohexanone derivatives and their inhibitory properties against some metabolic enzymes

(2018) Abdullah Biçer et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization, crystal structure of the coordination polymer Zn(II) with thiosemicarbazone of glyoxalic acid and their inhibitory properties against some metabolic enzymes

(2018) Mansura Huseynova et al.   BIOORGANIC CHEMISTRY

The first synthesis, carbonic anhydrase inhibition and anticholinergic activities of some bromophenol derivatives with S including natural products

(2018) Cetin Bayrak et al.   BIOORGANIC CHEMISTRY

Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors

(2017) Roberta Cadoni et al.   ACS Medicinal Chemistry Letters

Structure of human lysosomal acid α-glucosidase–a guide for the treatment of Pompe disease

(2017) Véronique Roig-Zamboni et al.   Nature Communications

In vitro inhibitory effects of palonosetron hydrochloride, bevacizumab and cyclophosphamide on purified paraoxonase-I (hPON1) from human serum

(2016) Cüneyt Türkeş et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Human serum paraoxonase-1 (hPON1):in vitroinhibition effects of moxifloxacin hydrochloride, levofloxacin hemihidrate, cefepime hydrochloride, cefotaxime sodium and ceftizoxime sodium

(2014) Cüneyt Türkeş et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Effect of calcium channel blockers on paraoxonase-1 (PON1) activity and oxidative stress

(2014) Cüneyt Türkeş et al.   Pharmacological Reports

Rapid screening and identification ofα-glucosidase inhibitors from mulberry leaves using enzyme-immobilized magnetic beads coupled with HPLC/MS and NMR

(2012) Yi Tao et al.   BIOMEDICAL CHROMATOGRAPHY

Synthesis and paroxonase activities of novel bromophenols

(2012) Yusuf Akbaba et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY