Senescence‐associated β‐galactosidase reveals the abundance of senescent CD8+ T cells in aging humans

Sestrins induce natural killer function in senescent-like CD8+ T cells

(2020) Branca I. Pereira et al.   NATURE IMMUNOLOGY

T cells with dysfunctional mitochondria induce multimorbidity and premature senescence

(2020) Gabriela Desdín-Micó et al.   SCIENCE

T cells, aging and senescence

(2020) Luca Pangrazzi et al.   EXPERIMENTAL GERONTOLOGY

AP-1 imprints a reversible transcriptional programme of senescent cells

(2020) Ricardo Iván Martínez-Zamudio et al.   NATURE CELL BIOLOGY

L1 drives IFN in senescent cells and promotes age-associated inflammation

(2019) Marco De Cecco et al.   NATURE

Senescent cell clearance by the immune system: Emerging therapeutic opportunities

(2019) Larissa G.P. Langhi Prata et al.   SEMINARS IN IMMUNOLOGY

Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition

(2019) Branca I. Pereira et al.   Nature Communications

Cellular senescence in development, regeneration and disease

(2019) Muriel Rhinn et al.   DEVELOPMENT

Cellular Senescence: Defining a Path Forward

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Mitochondrial mass governs the extent of human T cell senescence

(2019) Lauren A. Callender et al.   AGING CELL

T-cell Immunoglobulin and ITIM Domain Contributes to CD8+ T-cell Immunosenescence

(2018) Yangzi Song et al.   AGING CELL

Signaling and Function of Interleukin-2 in T Lymphocytes

(2018) Sarah H. Ross et al.   Annual Review of Immunology

Hallmarks of Cellular Senescence

(2018) Alejandra Hernandez-Segura et al.   TRENDS IN CELL BIOLOGY

Age-Related Decline in Primary CD8 + T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8 + T Cells

(2018) Kylie M. Quinn et al.   Cell Reports

Impaired immune surveillance accelerates accumulation of senescent cells and aging

(2018) Yossi Ovadya et al.   Nature Communications

Markers of T Cell Senescence in Humans

(2017) Weili Xu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Telomere Dynamics in Immune Senescence and Exhaustion Triggered by Chronic Viral Infection

(2017) Marcia Bellon et al.   Viruses-Basel

A topically-sprayable, activatable fluorescent and retaining probe, SPiDER-βGal for detecting cancer: Advantages of anchoring to cellular proteins after activation

(2017) Yuko Nakamura et al.   Oncotarget

Cellular senescence impact on immune cell fate and function

(2016) Rita Vicente et al.   AGING CELL

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses

(2016) Vesna Pulko et al.   NATURE IMMUNOLOGY

Mitochondrial Respiration Controls Lysosomal Function during Inflammatory T Cell Responses

(2015) Francesc Baixauli et al.   Cell Metabolism

limma powers differential expression analyses for RNA-sequencing and microarray studies

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The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8+ T cells

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Cellular senescence: from physiology to pathology

(2014) Daniel Muñoz-Espín et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit

(2014) Pavan Kumar Puvvula et al.   Nature Communications

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

(2012) Marzia Fumagalli et al.   NATURE CELL BIOLOGY

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence

(2012) Graeme Hewitt et al.   Nature Communications

Expression ofp16INK4ain peripheral blood T-cells is a biomarker of human aging

(2009) Yan Liu et al.   AGING CELL

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

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(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Phenotype and function of human T lymphocyte subsets: Consensus and issues

(2008) Victor Appay et al.   CYTOMETRY PART A

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY