Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration

Neuron-specific activation of necroptosis signaling in multiple sclerosis cortical grey matter

(2021) Carmen Picon et al.   ACTA NEUROPATHOLOGICA

Calming Neurons with a Microglial Touch

(2020) Kaushik Sharma et al.   TRENDS IN NEUROSCIENCES

Lymphoid Aggregates in the CNS of Progressive Multiple Sclerosis Patients Lack Regulatory T Cells

(2020) Luisa Bell et al.   Frontiers in Immunology

The CSF profile linked to cortical damage predicts Multiple Sclerosis activity

(2020) Roberta Magliozzi et al.   ANNALS OF NEUROLOGY

B cell rich meningeal inflammation associates with increased spinal cord pathology in multiple sclerosis

(2020) Camilla Reali et al.   BRAIN PATHOLOGY

Persistent elevation of intrathecal pro-inflammatory cytokines leads to multiple sclerosis-like cortical demyelination and neurodegeneration

(2020) Rachel E. James et al.   Acta Neuropathologica Communications

MetaboAnalystR 3.0: Toward an Optimized Workflow for Global Metabolomics

(2020) Zhiqiang Pang et al.   Metabolites

Synaptic Loss in Multiple Sclerosis Spinal Cord

(2020) Natalia Petrova et al.   ANNALS OF NEUROLOGY

Astrocytes and microglia play orchestrated roles and respect phagocytic territories during neuronal corpse removal in vivo

(2020) Eyiyemisi C. Damisah et al.   Science Advances

Neuronal vulnerability and multilineage diversity in multiple sclerosis

(2019) Lucas Schirmer et al.   NATURE

Microglial cell hyper-ramification and neuronal dendritic spine loss in the hippocampus and medial prefrontal cortex in a mouse model of PTSD

(2019) Kristie Leigh Smith et al.   BRAIN BEHAVIOR AND IMMUNITY

Progressive multiple sclerosis: from pathophysiology to therapeutic strategies

(2019) Simon Faissner et al.   NATURE REVIEWS DRUG DISCOVERY

Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease

(2019) Sebastian Werneburg et al.   IMMUNITY

Microglia monitor and protect neuronal function through specialized somatic purinergic junctions

(2019) Csaba Cserép et al.   SCIENCE

Progressive multiple sclerosis patients show substantial lesion activity that correlates with clinical disease severity and sex: a retrospective autopsy cohort analysis

(2018) Sabina Luchetti et al.   ACTA NEUROPATHOLOGICA

OUP accepted manuscript

(2018)   BRAIN

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

(2018) Aleksandra Deczkowska et al.   CELL

Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping

(2018) Giovanni Di Liberto et al.   CELL

Microglial signatures and their role in health and disease

(2018) Oleg Butovsky et al.   NATURE REVIEWS NEUROSCIENCE

Combination of cuprizone and experimental autoimmune encephalomyelitis to study inflammatory brain lesion formation and progression

(2017) Bernhard Josef Rüther et al.   GLIA

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

(2017) Susanne Krasemann et al.   IMMUNITY

Quantitative microglia analyses reveal diverse morphologic responses in the rat cortex after diffuse brain injury

(2017) Helena Morrison et al.   Scientific Reports

QuPath: Open source software for digital pathology image analysis

(2017) Peter Bankhead et al.   Scientific Reports

Altered microglia morphology and higher resilience to stress-induced depression-like behavior in CX3CR1-deficient mice

(2016) Sabine Hellwig et al.   BRAIN BEHAVIOR AND IMMUNITY

Complement C1q-C3-associated synaptic changes in multiple sclerosis hippocampus

(2015) Iliana Michailidou et al.   ANNALS OF NEUROLOGY

Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis

(2015) Tanja Jürgens et al.   BRAIN

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

What drives MRI-measured cortical atrophy in multiple sclerosis?

(2015) V Popescu et al.   Multiple Sclerosis Journal

Exploring the origins of grey matter damage in multiple sclerosis

(2015) Massimiliano Calabrese et al.   NATURE REVIEWS NEUROSCIENCE

Microglia: Dynamic Mediators of Synapse Development and Plasticity

(2015) Yuwen Wu et al.   TRENDS IN IMMUNOLOGY

What drives MRI-measured cortical atrophy in multiple sclerosis?

(2015) V Popescu et al.   Multiple Sclerosis Journal

Dendrite architecture organized by transcriptional control of the F-actin nucleator Spire

(2014) T. Ferreira et al.   DEVELOPMENT

Activation of Neuronal NMDA Receptors Triggers Transient ATP-Mediated Microglial Process Outgrowth

(2014) L. Dissing-Olesen et al.   JOURNAL OF NEUROSCIENCE

Defining the clinical course of multiple sclerosis: The 2013 revisions

(2014) F. D. Lublin et al.   NEUROLOGY

Microglial displacement of inhibitory synapses provides neuroprotection in the adult brain

(2014) Zhihong Chen et al.   Nature Communications

Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized rats

(2013) Christopher Gardner et al.   BRAIN

Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status

(2013) Daphne YS Vogel et al.   Journal of Neuroinflammation

Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis

(2013) Amanda Sierra et al.   Frontiers in Cellular Neuroscience

Cortical lesion load associates with progression of disability in multiple sclerosis

(2012) M. Calabrese et al.   BRAIN

Chronic Stress Induced Remodeling of the Prefrontal Cortex: Structural Re-Organization of Microglia and the Inhibitory Effect of Minocycline

(2012) M. Hinwood et al.   CEREBRAL CORTEX

Adenosine A3 receptor is involved in ADP-induced microglial process extension and migration

(2012) Keiko Ohsawa et al.   JOURNAL OF NEUROCHEMISTRY

Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis

(2011) Owain W. Howell et al.   BRAIN

Microglial Morphology and Dynamic Behavior Is Regulated by Ionotropic Glutamatergic and GABAergic Neurotransmission

(2011) Aurora M. Fontainhas et al.   PLoS One

A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis

(2010) Roberta Magliozzi et al.   ANNALS OF NEUROLOGY

Demyelination causes synaptic alterations in hippocampi from multiple sclerosis patients

(2010) Ranjan Dutta et al.   ANNALS OF NEUROLOGY

3D reconstruction of histological sections: Application to mammary gland tissue

(2010) Ignacio Arganda-Carreras et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET