Exploring the origins of grey matter damage in multiple sclerosis

High-throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV-reactive CD8+T cells

(2014) Andreas Lossius et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

What Explains Gray Matter Atrophy in Long-standing Multiple Sclerosis?

(2014) Martijn D. Steenwijk et al.   RADIOLOGY

The changing clinical course of multiple sclerosis: A matter of gray matter

(2013) Massimiliano Calabrese et al.   ANNALS OF NEUROLOGY

MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis

(2013) et al.   BRAIN

Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized rats

(2013) Christopher Gardner et al.   BRAIN

Disease-specific molecular events in cortical multiple sclerosis lesions

(2013) Marie Therese Fischer et al.   BRAIN

Radioactive in situ hybridization for Epstein–Barr virus–encoded small RNA supports presence of Epstein–Barr virus in the multiple sclerosis brain

(2013) Barbara Serafini et al.   BRAIN

Multiple sclerosis spasticity daily management: retrospective data from Europe

(2013) Thomas Berger   Expert Review of Neurotherapeutics

Cytotoxic NKG2C+ CD4 T Cells Target Oligodendrocytes in Multiple Sclerosis

(2013) F. Zaguia et al.   JOURNAL OF IMMUNOLOGY

Assessing the Correlation between Grey and White Matter Damage with Motor and Cognitive Impairment in Multiple Sclerosis Patients

(2013) Emilia Sbardella et al.   PLoS One

Neurons as targets for T cells in the nervous system

(2013) Roland S. Liblau et al.   TRENDS IN NEUROSCIENCES

Increased CD8+ T Cell Response to Epstein-Barr Virus Lytic Antigens in the Active Phase of Multiple Sclerosis

(2013) Daniela F. Angelini et al.   PLoS Pathogens

Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis

(2012) Sung R. Choi et al.   BRAIN

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

(2012) Marie T. Fischer et al.   BRAIN

B-Cell Enrichment and Epstein-Barr Virus Infection in Inflammatory Cortical Lesions in Secondary Progressive Multiple Sclerosis

(2012) Roberta Magliozzi et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The role of mitochondria in axonal degeneration and tissue repair in MS

(2012) J van Horssen et al.   Multiple Sclerosis Journal

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

Will the real multiple sclerosis please stand up?

(2012) Peter K. Stys et al.   NATURE REVIEWS NEUROSCIENCE

Heterogeneity of cortical lesions in multiple sclerosis: Clinical and pathologic implications

(2012) E.-J. Kooi et al.   NEUROLOGY

Epstein-Barr Virus Stimulates Torque Teno Virus Replication: A Possible Relationship to Multiple Sclerosis

(2012) Silvia S. Borkosky et al.   PLoS One

The neuropathological basis of clinical progression in multiple sclerosis

(2011) Richard Reynolds et al.   ACTA NEUROPATHOLOGICA

Epstein-Barr virus in the multiple sclerosis brain: a controversial issue--report on a focused workshop held in the Centre for Brain Research of the Medical University of Vienna, Austria

(2011) H. Lassmann et al.   BRAIN

Disability, atrophy and cortical reorganization following spinal cord injury

(2011) Patrick Freund et al.   BRAIN

Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis

(2011) Owain W. Howell et al.   BRAIN

Th17 Cells Induce Ectopic Lymphoid Follicles in Central Nervous System Tissue Inflammation

(2011) Anneli Peters et al.   IMMUNITY

Imaging the tip of the iceberg: visualization of cortical lesions in multiple sclerosis

(2011) Alexandra Seewann et al.   Multiple Sclerosis Journal

Grey matter volume in a large cohort of MS patients: relation to MRI parameters and disability

(2011) Stefan D Roosendaal et al.   Multiple Sclerosis Journal

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

In vivo evidence of disseminated subpial T2* signal changes in multiple sclerosis at 7 T: A surface-based analysis

(2011) J. Cohen-Adad et al.   NEUROIMAGE

Cortical lesions in radiologically isolated syndrome

(2011) A. Giorgio et al.   NEUROLOGY

Inflammatory Cortical Demyelination in Early Multiple Sclerosis

(2011) Claudia F. Lucchinetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Meningeal T cells associate with diffuse axonal loss in multiple sclerosis spinal cords

(2010) Géraldine Androdias et al.   ANNALS OF NEUROLOGY

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis

(2010) Graham R. Campbell et al.   ANNALS OF NEUROLOGY

A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis

(2010) Roberta Magliozzi et al.   ANNALS OF NEUROLOGY

Detection of Epstein–Barr virus and B-cell follicles in the multiple sclerosis brain: what you find depends on how and where you look

(2010) Francesca Aloisi et al.   BRAIN

Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis

(2010) Sergio E. Baranzini et al.   BRAIN

Spatiotemporal distribution pattern of white matter lesion volumes and their association with regional grey matter volume reductions in relapsing-remitting multiple sclerosis

(2010) Kerstin Bendfeldt et al.   HUMAN BRAIN MAPPING

Epstein–Barr Virus Infection and Multiple Sclerosis: A Review

(2010) Alberto Ascherio et al.   Journal of Neuroimmune Pharmacology

Atrophy mainly affects the limbic system and the deep grey matter at the first stage of multiple sclerosis

(2010) B. Audoin et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Mitochondrial dysfunction: A potential link between neuroinflammation and neurodegeneration?

(2010) Maarten E. Witte et al.   MITOCHONDRION

Cortical lesions in multiple sclerosis

(2010) Massimiliano Calabrese et al.   Nature Reviews Neurology

Imaging distribution and frequency of cortical lesions in patients with multiple sclerosis

(2010) M. Calabrese et al.   NEUROLOGY

Absence of Epstein-Barr virus in the brain and CSF of patients with multiple sclerosis

(2010) S. A. Sargsyan et al.   NEUROLOGY

Multiple sclerosis: Distribution of inflammatory cells in newly forming lesions

(2009) Andrew P. D. Henderson et al.   ANNALS OF NEUROLOGY

Contribution of White Matter Lesions to Gray Matter Atrophy in Multiple Sclerosis

(2009) Jorge Sepulcre et al.   ARCHIVES OF NEUROLOGY

Epstein–Barr virus infection is not a characteristic feature of multiple sclerosis brain

(2009) Simon N. Willis et al.   BRAIN

Demyelination, Inflammation, and Neurodegeneration in Multiple Sclerosis Deep Gray Matter

(2009) Marco Vercellino et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Meningeal Inflammation is not Associated With Cortical Demyelination in Chronic Multiple Sclerosis

(2009) Evert-Jan Kooi et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cytotoxic CD8+ T Cell-Neuron Interactions: Perforin-Dependent Electrical Silencing Precedes But Is Not Causally Linked to Neuronal Cell Death

(2009) S. G. Meuth et al.   JOURNAL OF NEUROSCIENCE

Voxel-wise assessment of progression of regional brain atrophy in relapsing-remitting multiple sclerosis

(2009) Marco Battaglini et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Grey matter pathology in clinically early multiple sclerosis: Evidence from magnetic resonance imaging

(2009) Declan Chard et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

White matter hemodynamic abnormalities precede sub-cortical gray matter changes in multiple sclerosis

(2009) Andrew W. Varga et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Connecting white matter injury and thalamic atrophy in clinically isolated syndromes

(2009) Roland G. Henry et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

(2009) Bruce D Trapp et al.   LANCET NEUROLOGY

Different white matter lesion characteristics correlate with distinct grey matter abnormalities on magnetic resonance imaging in secondary progressive multiple sclerosis

(2009) J Furby et al.   Multiple Sclerosis Journal

Magnetic resonance evidence of cortical onset of multiple sclerosis

(2009) M Calabrese et al.   Multiple Sclerosis Journal

Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis

(2009) Gurumoorthy Krishnamoorthy et al.   NATURE MEDICINE

Mitochondrial defects in acute multiple sclerosis lesions

(2008) Don Mahad et al.   BRAIN

Spinal Cord Neuronal Pathology in Multiple Sclerosis

(2008) Christopher P. Gilmore et al.   BRAIN PATHOLOGY

Interferon-γ directly induces neurotoxicity through a neuron specific, calcium-permeable complex of IFN-γ receptor and AMPA GluR1 receptor

(2008) Tetsuya Mizuno et al.   FASEB JOURNAL

Regional variations in the extent and pattern of grey matter demyelination in multiple sclerosis: a comparison between the cerebral cortex, cerebellar cortex, deep grey matter nuclei and the spinal cord

(2008) C P Gilmore et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Elevated Matrix Metalloproteinase-9 and Degradation of Perineuronal Nets in Cerebrocortical Multiple Sclerosis Plaques

(2008) Elizabeth Gray et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mitochondrial DNA repair in aging and disease

(2008) Nadiya M. Druzhyna et al.   MECHANISMS OF AGEING AND DEVELOPMENT

A voxel-based morphometry study of grey matter loss in MS patients with different clinical phenotypes

(2008) Antonia Ceccarelli et al.   NEUROIMAGE

Association of regional gray matter volume loss and progression of white matter lesions in multiple sclerosis — A longitudinal voxel-based morphometry study

(2008) Kerstin Bendfeldt et al.   NEUROIMAGE