Arsenic trioxide induces differentiation of cancer stem cells in hepatocellular carcinoma through inhibition of LIF/JAK1/STAT3 and NF‐kB signaling pathways synergistically

The expanding roles of long non-coding RNAs in the regulation of cancer stem cells

(2019) Zhaowu Ma et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Sphere-forming culture enriches liver cancer stem cells and reveals Stearoyl-CoA desaturase 1 as a potential therapeutic target

(2019) Xiao-Lu Ma et al.   BMC CANCER

Arsenic trioxide inhibits liver cancer stem cells and metastasis by targeting SRF/MCM7 complex

(2019) Hai-Yang Wang et al.   Cell Death & Disease

EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma

(2018) Peter R. Galle et al.   JOURNAL OF HEPATOLOGY

Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial

(2018) Masatoshi Kudo et al.   LANCET

Molecular remission as a therapeutic objective in acute promyelocytic leukemia

(2018) Laura Cicconi et al.   LEUKEMIA

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Arsenic trioxide intravenous infusion combined with transcatheter arterial chemoembolization for the treatment of hepatocellular carcinoma with pulmonary metastasis: Long-term outcome analysis

(2017) Hong Tao Hu et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Inhibition of cancer growth in vitro and in vivo by a novel ROS-modulating agent with ability to eliminate stem-like cancer cells

(2017) Jiankang Wang et al.   Cell Death & Disease

The Burden of Primary Liver Cancer and Underlying Etiologies From 1990 to 2015 at the Global, Regional, and National Level

(2017) et al.   JAMA Oncology

Regulation of the p53 response and its relationship to cancer

(2015) David W. Meek   BIOCHEMICAL JOURNAL

Randomized clinical control study of locoregional therapy combined with arsenic trioxide for the treatment of hepatocellular carcinoma

(2015) Hui Wang et al.   CANCER

Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma

(2015) Maria Romina Girotti et al.   CANCER CELL

Promyelocytic leukemia protein induces arsenic trioxide resistance through regulation of aldehyde dehydrogenase 3 family member A1 in hepatocellular carcinoma

(2015) Xin Zhang et al.   CANCER LETTERS

Preclinical Mouse Cancer Models: A Maze of Opportunities and Challenges

(2015) Chi-Ping Day et al.   CELL

LIF signaling in stem cells and development

(2015) K. Onishi et al.   DEVELOPMENT

Systemic treatment of advanced hepatocellular carcinoma: From disillusions to new horizons

(2015) Antoine Hollebecque et al.   EUROPEAN JOURNAL OF CANCER

Comparative gene-expression profiling of CD133+ and CD133- D10 melanoma cells

(2015) Raheleh Roudi et al.   Future Oncology

Arsenic trioxide-based therapy of relapsed acute promyelocytic leukemia: registry results from the European LeukemiaNet

(2015) E Lengfelder et al.   LEUKEMIA

Abnormal Wnt signaling and overexpression of ABCG2 contributes to drug efflux properties of side population cells in nasopharyngeal carcinoma

(2015) GUO-FANG GUAN et al.   Molecular Medicine Reports

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model

(2015) Kodappully Sivaraman Siveen et al.   Oncotarget

Hepatocellular carcinoma: clinical frontiers and perspectives

(2014) Jordi Bruix et al.   GUT

Arsenic trioxide induces differentiation of CD133+ hepatocellular carcinoma cells and prolongs posthepatectomy survival by targeting GLI1 expression in a mouse model

(2014) Ke-Zhi Zhang et al.   Journal of Hematology & Oncology

HCC therapies—lessons learned

(2014) Marcus-Alexander Wörns et al.   Nature Reviews Gastroenterology & Hepatology

Adjuvant and chemopreventive therapies for resectable hepatocellular carcinoma: a literature review

(2014) Jian-Hong Zhong et al.   TUMOR BIOLOGY

Emerging role of the β-catenin-PPARγ axis in the pathogenesis of colorectal cancer

(2014) Lina Sabatino   WORLD JOURNAL OF GASTROENTEROLOGY

One mouse, one patient paradigm: New avatars of personalized cancer therapy

(2013) Prerna Malaney et al.   CANCER LETTERS

Hepatocellular carcinoma and sorafenib: too many resistance mechanisms?

(2013) Carmen Berasain   GUT

Differentiation therapy for solid tumors

(2013) Wen Ping Xu et al.   Journal of Digestive Diseases

Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance

(2013) Meghna Das Thakur et al.   NATURE

Retinoic Acid and Arsenic Trioxide for Acute Promyelocytic Leukemia

(2013) Francesco Lo-Coco et al.   NEW ENGLAND JOURNAL OF MEDICINE

Redox regulation in stem-like cancer cells by CD44 variant isoforms

(2013) O Nagano et al.   ONCOGENE

Arsenic trioxide induces cervical cancer apoptosis, but specifically targets human papillomavirus-infected cell populations

(2012) Xuesong Wen et al.   ANTI-CANCER DRUGS

BMP4 Administration Induces Differentiation of CD133+Hepatic Cancer Stem Cells, Blocking Their Contributions to Hepatocellular Carcinoma

(2012) Lixing Zhang et al.   CANCER RESEARCH

CD133+ liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling

(2011) Kwan Ho Tang et al.   HEPATOLOGY

Impact of arsenic trioxide in the treatment of acute promyelocytic leukemia

(2011) E Lengfelder et al.   LEUKEMIA

Metastasis: cancer cell’s escape from oxidative stress

(2010) Giovambattista Pani et al.   CANCER AND METASTASIS REVIEWS

Mammosphere-forming cells from breast cancer cell lines as a tool for the identification of CSC-like- and early progenitor-targeting drugs

(2010) Mario Cioce et al.   CELL CYCLE

Finding cancer stem cells: are aldehyde dehydrogenases fit for purpose?

(2010) Malcolm R Alison et al.   JOURNAL OF PATHOLOGY

As4S4 targets RING-type E3 ligase c-CBL to induce degradation of BCR-ABL in chronic myelogenous leukemia

(2010) J.-H. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer stem cells in solid tumors

(2010) Patrick C. Hermann et al.   SEMINARS IN CANCER BIOLOGY

Cytotoxicity of single-walled carbon nanotubes on PC12 cells

(2010) Jingyun Wang et al.   TOXICOLOGY IN VITRO

Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

(2009) Heehyoung Lee et al.   CANCER CELL

Human Glioblastoma-Derived Cancer Stem Cells: Establishment of Invasive Glioma Models and Treatment with Oncolytic Herpes Simplex Virus Vectors

(2009) H. Wakimoto et al.   CANCER RESEARCH

Cancer stem/progenitor cells are highly enriched in CD133+CD44+population in hepatocellular carcinoma

(2009) Zheng Zhu et al.   INTERNATIONAL JOURNAL OF CANCER

Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial

(2008) Ann-Lii Cheng et al.   LANCET ONCOLOGY

Sorafenib in Advanced Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   NEW ENGLAND JOURNAL OF MEDICINE