Sphere-forming culture enriches liver cancer stem cells and reveals Stearoyl-CoA desaturase 1 as a potential therapeutic target

Induction of cancer cell stemness by depletion of macrohistone H2A1 in hepatocellular carcinoma

(2018) Oriana Lo Re et al.   HEPATOLOGY

Histone variant macroH2A1 rewires carbohydrate and lipid metabolism of hepatocellular carcinoma cells towards cancer stem cells

(2018) Oriana Lo Re et al.   Epigenetics

Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6

(2017) Keane K.Y. Lai et al.   GASTROENTEROLOGY

EMT, CSCs, and drug resistance: the mechanistic link and clinical implications

(2017) Tsukasa Shibue et al.   Nature Reviews Clinical Oncology

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ

(2017) A Noto et al.   ONCOGENE

MicroRNA-141 suppresses prostate cancer stem cells and metastasis by targeting a cohort of pro-metastasis genes

(2017) Can Liu et al.   Nature Communications

SIRT6 Suppresses Cancer Stem-like Capacity in Tumors with PI3K Activation Independently of Its Deacetylase Activity

(2017) Rafael M. Ioris et al.   Cell Reports

miR-600 Acts as a Bimodal Switch that Regulates Breast Cancer Stem Cell Fate through WNT Signaling

(2017) Rita El Helou et al.   Cell Reports

Stearoyl CoA desaturase-1: New insights into a central regulator of cancer metabolism

(2016) R. Ariel Igal   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Clinical and microarray analysis of breast cancers of all subtypes from two prospective preoperative chemotherapy studies

(2016) H S Okuma et al.   BRITISH JOURNAL OF CANCER

Administration of Non-Torsadogenic human Ether-à-go-go-Related Gene Inhibitors Is Associated with Better Survival for High hERG–Expressing Glioblastoma Patients

(2016) Kelli B. Pointer et al.   CLINICAL CANCER RESEARCH

Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma

(2016) Jordi Bruix et al.   GASTROENTEROLOGY

Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2

(2016) Stephen B. Keysar et al.   JNCI-Journal of the National Cancer Institute

CD51 correlates with the TGF-beta pathway and is a functional marker for colorectal cancer stem cells

(2016) J Wang et al.   ONCOGENE

Peroxiredoxin II Is Essential for Maintaining Stemness by Redox Regulation in Liver Cancer Cells

(2016) Taeho Kwon et al.   STEM CELLS

Three-dimensional Organotypic Culture Models of Human Hepatocellular Carcinoma

(2016) Atsushi Takai et al.   Scientific Reports

Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2

(2016) Stephen B. Keysar et al.   JNCI-Journal of the National Cancer Institute

Stearoyl-CoA desaturase 1 and paracrine diffusible signals have a major role in the promotion of breast cancer cell migration induced by cancer-associated fibroblasts

(2015) C Angelucci et al.   BRITISH JOURNAL OF CANCER

SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK signaling pathway

(2015) Guang-Ming Huang et al.   CANCER LETTERS

Potential molecular, cellular and microenvironmental mechanism of sorafenib resistance in hepatocellular carcinoma

(2015) Jiang Chen et al.   CANCER LETTERS

Cancer Stem Cells: Targeting the Roots of Cancer, Seeds of Metastasis, and Sources of Therapy Resistance

(2015) V. Adorno-Cruz et al.   CANCER RESEARCH

Heterogeneity of hepatocellular carcinoma contributes to cancer progression

(2015) Kuo-Shyang Jeng et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Hepatocellular carcinoma: clinical frontiers and perspectives

(2014) Jordi Bruix et al.   GUT

Integrated Metabolite and Gene Expression Profiles Identify Lipid Biomarkers Associated With Progression of Hepatocellular Carcinoma and Patient Outcomes

(2013) Anuradha Budhu et al.   GASTROENTEROLOGY

Expression of Intercellular Adhesion Molecule 1 by Hepatocellular Carcinoma Stem Cells and Circulating Tumor Cells

(2013) Shupeng Liu et al.   GASTROENTEROLOGY

Tumour heterogeneity and cancer cell plasticity

(2013) Corbin E. Meacham et al.   NATURE

Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty

(2012) Jeffrey A. Magee et al.   CANCER CELL

CD133+EpCAM+ Phenotype Possesses More Characteristics of Tumor Initiating Cells in Hepatocellular Carcinoma Huh7 Cells

(2012) Yi Chen et al.   International Journal of Biological Sciences

OV6+ tumor-initiating cells contribute to tumor progression and invasion in human hepatocellular carcinoma

(2012) Wen Yang et al.   JOURNAL OF HEPATOLOGY

CD24+ Liver Tumor-Initiating Cells Drive Self-Renewal and Tumor Initiation through STAT3-Mediated NANOG Regulation

(2011) Terence Kin Wah Lee et al.   Cell Stem Cell

Eyes Wide Open: A Critical Review of Sphere-Formation as an Assay for Stem Cells

(2011) Erika Pastrana et al.   Cell Stem Cell

Management of hepatocellular carcinoma: An update

(2011) Jordi Bruix et al.   HEPATOLOGY

miR-130b Promotes CD133+ Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1

(2010) Stephanie Ma et al.   Cell Stem Cell

CD13 is a therapeutic target in human liver cancer stem cells

(2010) Naotsugu Haraguchi et al.   JOURNAL OF CLINICAL INVESTIGATION

EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features

(2008) Taro Yamashita et al.   GASTROENTEROLOGY

Identification of local and circulating cancer stem cells in human liver cancer

(2008) Zhen Fan Yang et al.   HEPATOLOGY