Arsenic trioxide inhibits liver cancer stem cells and metastasis by targeting SRF/MCM7 complex

Arsenic trioxide intravenous infusion combined with transcatheter arterial chemoembolization for the treatment of hepatocellular carcinoma with pulmonary metastasis: Long-term outcome analysis

(2017) Hong Tao Hu et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

MCM7 promotes cancer progression through cyclin D1-dependent signaling and serves as a prognostic marker for patients with hepatocellular carcinoma

(2017) Kai Qu et al.   Cell Death & Disease

Hepatocellular carcinoma

(2016) Josep M. Llovet et al.   Nature Reviews Disease Primers

Hepatocellular carcinoma cell lines retain the genomic and transcriptomic landscapes of primary human cancers

(2016) Zhixin Qiu et al.   Scientific Reports

Randomized clinical control study of locoregional therapy combined with arsenic trioxide for the treatment of hepatocellular carcinoma

(2015) Hui Wang et al.   CANCER

MicroRNA-125b attenuates epithelial-mesenchymal transitions and targets stem-like liver cancer cells through small mothers against decapentaplegic 2 and 4

(2015) Jun-Nian Zhou et al.   HEPATOLOGY

Dysregulated serum response factor triggers formation of hepatocellular carcinoma

(2015) Stefan Ohrnberger et al.   HEPATOLOGY

Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic

(2015) Hai-nan Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cancer stem cell gamble

(2015) J. Kaiser   SCIENCE

Spherical Cancer Models in Tumor Biology

(2015) Louis-Bastien Weiswald et al.   NEOPLASIA

Evolution of the Cancer Stem Cell Model

(2014) Antonija Kreso et al.   Cell Stem Cell

Hepatocellular carcinoma: clinical frontiers and perspectives

(2014) Jordi Bruix et al.   GUT

The Reaction of Arsenite with Proteins Relies on Solution Conditions

(2014) Linhong Zhao et al.   INORGANIC CHEMISTRY

Arsenic trioxide transarterial chemoembolization with and without additional intravenous administration of arsenic trioxide in unresectable hepatocellular carcinoma with lung metastasis: a single-blind, randomized trial

(2014) Bing Liu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Arsenic trioxide induces differentiation of CD133+ hepatocellular carcinoma cells and prolongs posthepatectomy survival by targeting GLI1 expression in a mouse model

(2014) Ke-Zhi Zhang et al.   Journal of Hematology & Oncology

Inhibition of the Cancer Stem Cells-Like Properties by Arsenic Trioxide, Involved in the Attenuation of Endogenous Transforming Growth Factor Beta Signal

(2014) Yuan Li et al.   TOXICOLOGICAL SCIENCES

The Mcm2-7 Replicative Helicase: A Promising Chemotherapeutic Target

(2014) Nicholas E. Simon et al.   Biomed Research International

Epidermal Growth Factor Receptor Potentiates MCM7-Mediated DNA Replication through Tyrosine Phosphorylation of Lyn Kinase in Human Cancers

(2013) Tzu-Hsuan Huang et al.   CANCER CELL

Double-Edged Effects of Arsenic Compounds: Anticancer and Carcinogenic Effects

(2013) Kanwal Rehman et al.   CURRENT DRUG METABOLISM

Hepatocellular carcinoma-associated mesenchymal stem cells promote hepatocarcinoma progression: Role of the S100A4-miR155-SOCS1-MMP9 axis

(2013) Xin-Long Yan et al.   HEPATOLOGY

Depletion of minichromosome maintenance protein 7 inhibits glioblastoma multiforme tumor growth in vivo

(2013) E P Erkan et al.   ONCOGENE

A drug from poison: how the therapeutic effect of arsenic trioxide on acute promyelocytic leukemia was discovered

(2013) Yi Rao et al.   Science China-Life Sciences

Arsenic trioxide depletes cancer stem-like cells and inhibits repopulation of neurosphere derived from glioblastoma by downregulation of Notch pathway

(2013) Jianing Wu et al.   TOXICOLOGY LETTERS

Arsenic trioxide inhibits viability of pancreatic cancer stem cells in culture and in a xenograft model via binding to SHH-Gli

(2013) Jin-bin Han et al.   OncoTargets and Therapy

Arsenic compounds: revived ancient remedies in the fight against human malignancies

(2012) Jian-Xiang Liu et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

MCM7 expression predicts post-operative prognosis for hepatocellular carcinoma

(2012) Yan-Ming Zhou et al.   LIVER INTERNATIONAL

MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits

(2012) Hong Liu et al.   NATURE CELL BIOLOGY

Epimorphin promotes human hepatocellular carcinoma invasion and metastasis through activation of focal adhesion kinase/extracellular signal-regulated kinase/matrix metalloproteinase-9 axis

(2011) Ya-Li Jia et al.   HEPATOLOGY

CD13 is a therapeutic target in human liver cancer stem cells

(2010) Naotsugu Haraguchi et al.   JOURNAL OF CLINICAL INVESTIGATION

Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion

(2010) K-M Lau et al.   ONCOGENE

Arsenic Trioxide Controls the Fate of the PML-RAR  Oncoprotein by Directly Binding PML

(2010) X. W. Zhang et al.   SCIENCE

Serum response factor: Look into the gut

(2010) Cristina Modak   WORLD JOURNAL OF GASTROENTEROLOGY

Arsenic trioxide-mediated Notch pathway inhibition depletes the cancer stem-like cell population in gliomas

(2009) Yunbo Zhen et al.   CANCER LETTERS

EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features

(2008) Taro Yamashita et al.   GASTROENTEROLOGY