Oxidatively Modified LDL Suppresses Lymphangiogenesis via CD36 Signaling

Role of R-spondin 2 in arterial lymphangiogenesis and atherosclerosis

(2020) Bhupesh Singla et al.   CARDIOVASCULAR RESEARCH

S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress–dependent VEGF-C signaling

(2020) Xin Geng et al.   JCI Insight

Oxidized Low-Density Lipoprotein Drives Dysfunction of the Liver Lymphatic System

(2020) Matthew A. Burchill et al.   Cellular and Molecular Gastroenterology and Hepatology

The homeoviscous adaptation to dietary lipids (HADL) model explains controversies over saturated fat, cholesterol, and cardiovascular disease risk

(2020) Marit Kolby Zinöcker et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Efficient aortic lymphatic drainage is necessary for atherosclerosis regression induced by ezetimibe

(2020) Kim Pin Yeo et al.   Science Advances

YAP and TAZ Negatively Regulate Prox1 During Developmental and Pathologic Lymphangiogenesis

(2019) Hyunsoo Cho et al.   CIRCULATION RESEARCH

2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease

(2019) Donna K. Arnett et al.   CIRCULATION

Vascular Endothelial Growth Factor–D (VEGF-D) Overexpression and Lymphatic Expansion in Murine Adipose Tissue Improves Metabolism in Obesity

(2019) Adri Chakraborty et al.   AMERICAN JOURNAL OF PATHOLOGY

SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis

(2019) Linzhang Huang et al.   NATURE

Cholesterol versus Inflammation as Cause of Chronic Diseases

(2019) Panchal et al.   Nutrients

Paclitaxel induces lymphatic endothelial cells autophagy to promote metastasis

(2019) Audrey Zamora et al.   Cell Death & Disease

Enhancing Renal Lymphatic Expansion Prevents Hypertension in MiceNovelty and Significance

(2018) Catalina A. Lopez Gelston et al.   CIRCULATION RESEARCH

Multiple functions of p27 in cell cycle, apoptosis, epigenetic modification and transcriptional regulation for the control of cell growth: A double-edged sword protein

(2018) Maryam Abbastabar et al.   DNA REPAIR

Oxidized low-density lipoprotein in inflammation-driven thrombosis

(2018) G. Obermayer et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Inflammation, not Cholesterol, Is a Cause of Chronic Disease

(2018) Alexandros Tsoupras et al.   Nutrients

PKCδ stimulates macropinocytosis via activation of SSH1-cofilin pathway

(2018) Bhupesh Singla et al.   CELLULAR SIGNALLING

Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes

(2018) Hao Wu et al.   JOURNAL OF CLINICAL INVESTIGATION

Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel

(2017) Brian A. Ference et al.   EUROPEAN HEART JOURNAL

Vascular endothelial growth factor-C ameliorates renal interstitial fibrosis through lymphangiogenesis in mouse unilateral ureteral obstruction

(2017) Shoko Hasegawa et al.   LABORATORY INVESTIGATION

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1

(2017) Daniel N. Meijles et al.   Science Signaling

Adventitial lymphatic capillary expansion impacts on plaque T cell accumulation in atherosclerosis

(2017) Timo Rademakers et al.   Scientific Reports

The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1

(2017) Daniel N. Meijles et al.   Science Signaling

Phenotypic transformation of intimal and adventitial lymphatics in atherosclerosis: a regulatory role for soluble VEGF receptor 2

(2016) Mahdi Taher et al.   FASEB JOURNAL

Oxidized LDL induces FAK-dependent RSK signaling to drive NF-κB activation and VCAM-1 expression

(2016) Arif Yurdagul et al.   JOURNAL OF CELL SCIENCE

Excess Lymphangiogenesis Cooperatively Induced by Macrophages and CD4+ T Cells Drives the Pathogenesis of Lymphedema

(2016) Fusa Ogata et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The role of fatty acid β-oxidation in lymphangiogenesis

(2016) Brian W. Wong et al.   NATURE

Pericoronary Adipose Tissue as Storage and Supply Site for Oxidized Low-Density Lipoprotein in Human Coronary Plaques

(2016) Yasumi Uchida et al.   PLoS One

Curcumin Suppresses Proliferation and Migration of MDA-MB-231 Breast Cancer Cells through Autophagy-Dependent Akt Degradation

(2016) Feng Guan et al.   PLoS One

Lymphatic vascular integrity is disrupted in type 2 diabetes due to impaired nitric oxide signalling

(2015) Joshua P. Scallan et al.   CARDIOVASCULAR RESEARCH

The Biphasic Effects of Oxidized-Low Density Lipoprotein on the Vasculogenic Function of Endothelial Progenitor Cells

(2015) Feng-Yen Lin et al.   PLoS One

AKT hyper-phosphorylation associated with PI3K mutations in lymphatic endothelial cells from a patient with lymphatic malformation

(2014) Elisa Boscolo et al.   ANGIOGENESIS

Lymphatic Vessel Insufficiency in Hypercholesterolemic Mice Alters Lipoprotein Levels and Promotes Atherogenesis

(2014) Taina Vuorio et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

An activator of mTOR inhibits oxLDL-induced autophagy and apoptosis in vascular endothelial cells and restricts atherosclerosis in apolipoprotein E-/- mice

(2014) Nan Peng et al.   Scientific Reports

Lymphatic Vessels Are Essential for the Removal of Cholesterol from Peripheral Tissues by SR-BI-Mediated Transport of HDL

(2013) Hwee Ying Lim et al.   Cell Metabolism

Regulation of autophagy and apoptosis in response to ox-LDL in vascular smooth muscle cells, and the modulatory effects of the microRNA hsa-let-7g

(2013) Zufeng Ding et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice

(2013) Catherine Martel et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammation in Atherosclerosis

(2012) Peter Libby   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Current Concepts of the Role of Oxidized LDL Receptors in Atherosclerosis

(2012) Tanu Goyal et al.   Current Atherosclerosis Reports

IGFBP-rP1 induces p21 expression through a p53-independent pathway, leading to cellular senescence of MCF-7 breast cancer cells

(2012) Shuguang Zuo et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Collaborative interplay between FGF-2 and VEGF-C promotes lymphangiogenesis and metastasis

(2012) R. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesis

(2012) M. M. P. Schulz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Akt: A Double-Edged Sword in Cell Proliferation and Genome Stability

(2012) Naihan Xu et al.   Journal of Oncology

Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile

(2010) Latisha Love-Gregory et al.   HUMAN MOLECULAR GENETICS

Hypercholesterolemic Mice Exhibit Lymphatic Vessel Dysfunction and Degeneration

(2009) Hwee Ying Lim et al.   AMERICAN JOURNAL OF PATHOLOGY

Combination of Reverse and Chemical Genetic Screens Reveals Angiogenesis Inhibitors and Targets

(2009) Mattias Kalén et al.   CHEMISTRY & BIOLOGY

Adventitial lymphatics of internal carotid artery in healthy and atherosclerotic vessels.

(2009) Katarzyna Drozdz et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Oxidized low density lipoprotein-induced transdifferentiation of bone marrow-derived smooth muscle-like cells into foam-like cellsin vitro

(2009) Jun Yu et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

A Specific CD36-Dependent Signaling Pathway Is Required for Platelet Activation by Oxidized Low-Density Lipoprotein

(2008) Kan Chen et al.   CIRCULATION RESEARCH

Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad

(2008) S.-F. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA