The Immunogenicity of Capsid-Like Particle Vaccines in Combination with Different Adjuvants Using Different Routes of Administration

Plant-derived virus-like particle vaccines drive cross-presentation of influenza A hemagglutinin peptides by human monocyte-derived macrophages

(2019) Alexander I. Makarkov et al.   npj Vaccines

Pfs230 and Pfs48/45 Fusion Proteins Elicit Strong Transmission-Blocking Antibody Responses Against Plasmodium falciparum

(2019) Susheel K. Singh et al.   Frontiers in Immunology

Qß Virus-like particle-based vaccine induces robust immunity and protects against tauopathy

(2019) Nicole M. Maphis et al.   npj Vaccines

Type of RNA Packed in VLPs Impacts IgG Class Switching—Implications for an Influenza Vaccine Design

(2019) Ariane C. Gomes et al.   Vaccines

Virus‐like particles for vaccination against cancer

(2019) Mona O. Mohsen et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

TLR8 combined withTLR3 or TLR4 agonists enhances DC-NK driven effector Tc1 cells

(2018) Mahyar Nouri-Shirazi et al.   IMMUNOLOGY LETTERS

Correlates of adjuvanticity: A review on adjuvants in licensed vaccines

(2018) Giuseppe Del Giudice et al.   SEMINARS IN IMMUNOLOGY

Features of Effective T Cell-Inducing Vaccines against Chronic Viral Infections

(2018) Eleni Panagioti et al.   Frontiers in Immunology

Virus-like particle display of HER2 induces potent anti-cancer responses

(2018) Arianna Palladini et al.   OncoImmunology

An Overview of Novel Adjuvants Designed for Improving Vaccine Efficacy

(2017) Srinivasa Reddy Bonam et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display

(2017) Susheel K. Singh et al.   VACCINE

Cellular and molecular synergy in AS01-adjuvanted vaccines results in an early IFNγ response promoting vaccine immunogenicity

(2017) Margherita Coccia et al.   npj Vaccines

Impact of adjuvants on CD4 + T cell and B cell responses to a protein antigen vaccine: Results from a phase II, randomized, multicenter trial

(2016) Geert Leroux-Roels et al.   CLINICAL IMMUNOLOGY

Adjuvant system AS01: helping to overcome the challenges of modern vaccines

(2016) Arnaud M. Didierlaurent et al.   Expert Review of Vaccines

Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses

(2016) Christoph M. Janitzek et al.   MALARIA JOURNAL

Vaccine adjuvants: Why and how

(2016) Dennis Christensen   Human Vaccines & Immunotherapeutics

PLGA particulate delivery systems for subunit vaccines: Linking particle properties to immunogenicity

(2016) A. L. Silva et al.   Human Vaccines & Immunotherapeutics

Bacterial superglue enables easy development of efficient virus-like particle based vaccines

(2016) Susan Thrane et al.   JOURNAL OF NANOBIOTECHNOLOGY

Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization

(2016) Karl D. Brune et al.   Scientific Reports

Sortase A-Mediated N-Terminal Modification of Cowpea Chlorotic Mottle Virus for Highly Efficient Cargo Loading

(2015) Lise Schoonen et al.   BIOCONJUGATE CHEMISTRY

His-tagged norovirus-like particles: A versatile platform for cellular delivery and surface display

(2015) Tiia Koho et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Identification of QS-21 as an Inflammasome-activating Molecular Component of Saponin Adjuvants

(2015) Robyn Marty-Roix et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

(2015)   LANCET

Efficacy of fewer than three doses of an HPV-16/18 AS04-adjuvanted vaccine: combined analysis of data from the Costa Rica Vaccine and PATRICIA trials

(2015) Aimée R Kreimer et al.   LANCET ONCOLOGY

A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA

(2015) Susan Thrane et al.   PLoS One

Affinity selection of epitope-based vaccines using a bacteriophage virus-like particle platform

(2015) John P O’Rourke et al.   Current Opinion in Virology

Cutting Edge: Alum Adjuvant Stimulates Inflammatory Dendritic Cells through Activation of the NALP3 Inflammasome

(2014) M. Kool et al.   JOURNAL OF IMMUNOLOGY

Comparison of long-term immunogenicity and safety of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine and HPV-6/11/16/18 vaccine in healthy women aged 18-45 years: End-of-study analysis of a Phase III randomized trial

(2014) Mark H Einstein et al.   Human Vaccines & Immunotherapeutics

Modern Subunit Vaccines: Development, Components, and Research Opportunities

(2013) Peter Michael Moyle et al.   ChemMedChem

The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination

(2013) M. Vono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alum increases antigen uptake, reduces antigen degradation and sustains antigen presentation by DCs in vitro

(2012) Tirth R. Ghimire et al.   IMMUNOLOGY LETTERS

A Comparative Study of Stress-mediated Immunological Functions with the Adjuvanticity of Alum

(2012) Yufei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A cationic vaccine adjuvant based on a saturated quaternary ammonium lipid have different in vivo distribution kinetics and display a distinct CD4 T cell-inducing capacity compared to its unsaturated analog

(2012) Dennis Christensen et al.   JOURNAL OF CONTROLLED RELEASE

Development of viral nanoparticles for efficient intracellular delivery

(2012) Zhuojun Wu et al.   Nanoscale

Targeting dendritic cells with nano-particulate PLGA cancer vaccine formulations

(2011) Samar Hamdy et al.   ADVANCED DRUG DELIVERY REVIEWS

Surface Functionalization of Virus-Like Particles by Direct Conjugation Using Azide−Alkyne Click Chemistry

(2011) Kedar G. Patel et al.   BIOCONJUGATE CHEMISTRY

Cationic liposomes as vaccine adjuvants

(2011) Dennis Christensen et al.   Expert Review of Vaccines

Evidence based route of administration of vaccines

(2011) Ian F. Cook   Human vaccines & immunotherapeutics

Virus-like particle based vaccines for Alzheimer disease

(2011) Bryce Chackerian   Human vaccines & immunotherapeutics

Selective Utilization of Toll-like Receptor and MyD88 Signaling in B Cells for Enhancement of the Antiviral Germinal Center Response

(2011) Baidong Hou et al.   IMMUNITY

Cross-presentation of epitopes on virus-like particles via the MHC I receptor recycling pathway

(2011) Stephanie J Win et al.   IMMUNOLOGY AND CELL BIOLOGY

The vesicle size of DDA:TDB liposomal adjuvants plays a role in the cell-mediated immune response but has no significant effect on antibody production

(2011) Malou Henriksen-Lacey et al.   JOURNAL OF CONTROLLED RELEASE

Pegylation of DDA:TDB liposomal adjuvants reduces the vaccine depot effect and alters the Th1/Th2 immune responses

(2011) Randip Kaur et al.   JOURNAL OF CONTROLLED RELEASE

The Danger Signal, Extracellular ATP, Is a Sensor for an Airborne Allergen and Triggers IL-33 Release and Innate Th2-Type Responses

(2011) Hideaki Kouzaki et al.   JOURNAL OF IMMUNOLOGY

Programming the magnitude and persistence of antibody responses with innate immunity

(2011) Sudhir Pai Kasturi et al.   NATURE

DNA released from dying host cells mediates aluminum adjuvant activity

(2011) Thomas Marichal et al.   NATURE MEDICINE

Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88

(2011) A. Seubert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting TLRs Expands the Antibody Repertoire in Response to a Malaria Vaccine

(2011) S. R. Wiley et al.   Science Translational Medicine

Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes

(2011) Samuele Calabro et al.   VACCINE

Comparison of the immunogenicity and safety ofCervarix™ andGardasil®human papillomavirus (HPV) cervical cancer vaccines in healthy women aged 18–45 years

(2010) Mark H. Einstein et al.   Human vaccines & immunotherapeutics

Liposomal cationic charge and antigen adsorption are important properties for the efficient deposition of antigen at the injection site and ability of the vaccine to induce a CMI response

(2010) Malou Henriksen-Lacey et al.   JOURNAL OF CONTROLLED RELEASE

Toll-like receptors - sentries in the B-cell response

(2009) Isabelle Bekeredjian-Ding et al.   IMMUNOLOGY

Alveolar Macrophages and Lung Dendritic Cells Sense RNA and Drive Mucosal IgA Responses

(2009) J. Bessa et al.   JOURNAL OF IMMUNOLOGY

Alum Induces Innate Immune Responses through Macrophage and Mast Cell Sensors, But These Sensors Are Not Required for Alum to Act As an Adjuvant for Specific Immunity

(2009) A. S. McKee et al.   JOURNAL OF IMMUNOLOGY

Virus-like Particle (VLP) Lymphatic Trafficking and Immune Response Generation After Immunization by Different Routes

(2009) Rafael Cubas et al.   JOURNAL OF IMMUNOTHERAPY

Nanoparticles target distinct dendritic cell populations according to their size

(2008) Vania Manolova et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

(2008) Mirjam Kool et al.   JOURNAL OF EXPERIMENTAL MEDICINE