The Application of Nanotechnology for the Diagnosis and Treatment of Brain Diseases and Disorders

Intravenous Immunomodulatory Nanoparticle Treatment for Traumatic Brain Injury

(2020) Sripadh Sharma et al.   ANNALS OF NEUROLOGY

Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association

(2020) Salim S. Virani et al.   CIRCULATION

Nanoparticle formulation and in vitro efficacy testing of the mitoNEET ligand NL-1 for drug delivery in a brain endothelial model of ischemic reperfusion-injury

(2020) Pushkar Saralkar et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Decreasing acute toxicity and suppressing colorectal carcinoma using Sorafenib-loaded nanoparticles

(2020) Ningxi Li et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

Multifunctional, CD44v6-Targeted ORMOSIL Nanoparticles Enhance Drugs Toxicity in Cancer Cells

(2020) Lucía Morillas-Becerril et al.   Nanomaterials

Plasma and Serum Alpha-Synuclein as a Biomarker of Diagnosis in Patients With Parkinson's Disease

(2020) Chun-Wei Chang et al.   Frontiers in Neurology

Gold Nanoparticles Crossing Blood-Brain Barrier Prevent HSV-1 Infection and Reduce Herpes Associated Amyloid-βsecretion

(2020) Rodriguez-Izquierdo I et al.   Journal of Clinical Medicine

Solid lipid nanoparticles enhanced the neuroprotective role of curcumin against epilepsy through activation of Bcl-2 family and P38 MAPK pathway

(2020) Ruiqi Huang et al.   ACS Chemical Neuroscience

Zinc oxide nanoparticles and l-carnitine effects on neuro-schistosomiasis mansoni induced in mice

(2020) Amira A. Bauomy   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

An Elvitegravir Nanoformulation Crosses the Blood–Brain Barrier and Suppresses HIV-1 Replication in Microglia

(2020) Yuqing Gong et al.   Viruses-Basel

Intravenously Administered, Retinoid Activating Nanoparticles Increase Lifespan and Reduce Neurodegeneration in the SOD1G93A Mouse Model of ALS

(2020) David X. Medina et al.   Frontiers in Bioengineering and Biotechnology

Self-assembled polydopamine nanoparticles improve treatment in Parkinson's disease model mice and suppress dopamine-induced dyskinesia

(2020) Long Binh Vong et al.   Acta Biomaterialia

Serum Tau Proteins as Potential Biomarkers for the Assessment of Alzheimer’s Disease Progression

(2020) Eunjoo Nam et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synthesis and characterization of nanoemulsion-mediated core crosslinked nanoparticles, and in vivo pharmacokinetics depending on the structural characteristics

(2020) Jun Matsuno et al.   JOURNAL OF CONTROLLED RELEASE

Neurotoxicity of aluminum oxide nanoparticles and their mechanistic role in dopaminergic neuron injury involving p53-related pathways

(2020) Huanliang Liu et al.   JOURNAL OF HAZARDOUS MATERIALS

Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism

(2020) Max Borsche et al.   BRAIN

Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine in Healthy Meningococcal-Naïve Children 2–9 Years of Age: A Phase III, Randomized Study

(2020) Carmen I. Baccarini et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Effect of silver nanoparticles on the solubility of methane and ethane in water

(2020) Mahboubeh Rahmati-Abkenar et al.   Journal of Natural Gas Science and Engineering

Effects of gold nanoparticles administration through behavioral and oxidative parameters in animal model of Parkinson’s disease

(2020) Emily da Silva Córneo et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Transport of PEGylated-PLA nanoparticles across a blood brain barrier model, entry into neuronal cells and in vivo brain bioavailability

(2020) Jean-Michel Rabanel et al.   JOURNAL OF CONTROLLED RELEASE

Fluorescent peptide nanoparticles to detect amyloid-beta aggregation in cerebrospinal fluid and serum for Alzheimer’s disease diagnosis and progression monitoring

(2020) Leming Sun et al.   CHEMICAL ENGINEERING JOURNAL

Neuropharmacokinetic Evaluation of Lactoferrin-Treated Indinavir-Loaded Nanoemulsions: Remarkable Brain Delivery Enhancement

(2019) Zahra Karami et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Global, regional, and national burden of multiple sclerosis 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2019) Mitchell T Wallin et al.   LANCET NEUROLOGY

Inflammasome proteins as biomarkers of traumatic brain injury

(2019) Nadine Kerr et al.   PLoS One

Cytotoxicity, dose-enhancement and radiosensitization of glioblastoma cells with rare earth nanoparticles

(2019) Victor M. Lu et al.   Artificial Cells Nanomedicine and Biotechnology

FM19G11-Loaded Gold Nanoparticles Enhance the Proliferation and Self-Renewal of Ependymal Stem Progenitor Cells Derived from ALS Mice

(2019) Stefania Marcuzzo et al.   Cells

The Neuromodulatory Effects of ω-3 Fatty Acids and Nano-Curcumin on the COX-2/ iNOS Network in Migraines: A Clinical Trial Study from Gene Expression to Clinical Symptoms

(2019) Mina Abdolahi et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Novel sustainable-by-design HDAC inhibitors for the treatment of Alzheimer’s disease

(2019) Luiz A. S. Romeiro et al.   ACS Medicinal Chemistry Letters

Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer’s Disease

(2019) Angela De Simone et al.   ACS Medicinal Chemistry Letters

A Novel Contrast Agent Based on Magnetic Nanoparticles for Cholesterol Detection as Alzheimer’s Disease Biomarker

(2019) Tamara Fernández-Cabada et al.   Nanoscale Research Letters

Superparamagnetic iron oxide nanoparticles combined with NGF and quercetin promote neuronal branching morphogenesis of PC12 cells

(2019) Samira Katebi et al.   International Journal of Nanomedicine

Intraperitoneal delivery of acetate-encapsulated liposomal nanoparticles for neuroprotection of the penumbra in a rat model of ischemic stroke

(2019) Po-Wah So et al.   International Journal of Nanomedicine

Development of sorafenib loaded nanoparticles to improve oral bioavailability using a quality by design approach

(2019) Sang Yeob Park et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Design of Astaxanthin-Loaded Core–Shell Nanoparticles Consisting of Chitosan Oligosaccharides and Poly(lactic-co-glycolic acid): Enhancement of Water Solubility, Stability, and Bioavailability

(2019) Chengzhen Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Bioavailability Enhancement of Astilbin in Rats through Zein–Caseinate Nanoparticles

(2019) Dan Zheng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antidiabetic Drugs and Their Nanoconjugates Repurposed as Novel Antimicrobial Agents against Acanthamoeba castellanii

(2019) Ayaz Anwar et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Vitamin D-binding protein-loaded PLGA nanoparticles suppress Alzheimer's disease-related pathology in 5XFAD mice

(2019) Seong Gak Jeon et al.   Nanomedicine-Nanotechnology Biology and Medicine

Iron Oxide Nanoparticles Affects Behaviour and Monoamine Levels in Mice

(2019) Vijayprakash Manickam et al.   NEUROCHEMICAL RESEARCH

Vitamin E Loaded Naringenin Nanoemulsion via Intranasal Delivery for the Management of Oxidative Stress in a 6-OHDA Parkinson’s Disease Model

(2019) Bharti Gaba et al.   Biomed Research International

Improving Sensitivity and Specificity of Amyloid-β Peptide and Tau Protein Detection with Anti-Biofouling Magnetic Nanoparticles for Liquid Biopsy of Alzheimer’s Disease

(2019) Yuancheng Li et al.   ACS Biomaterials-Science & Engineering

Cancer-selective nanoparticles for combinatorial siRNA delivery to primary human GBM in vitro and in vivo

(2019) Kristen L. Kozielski et al.   BIOMATERIALS

CYP46A1 gene therapy deciphers the role of brain cholesterol metabolism in Huntington’s disease

(2019) Radhia Kacher et al.   BRAIN

Cell penetrating peptide-modified nanoparticles for tumor targeted imaging and synergistic effect of sonodynamic/HIFU therapy

(2019) Yizhen Li et al.   International Journal of Nanomedicine

Subchronic toxicity of silica nanoparticles as a function of size and porosity

(2019) Raziye Mohammadpour et al.   JOURNAL OF CONTROLLED RELEASE

Cobalt nanoparticles as novel nanotherapeutics against Acanthamoeba castellanii

(2019) Ayaz Anwar et al.   Parasites & Vectors

Exposure to carbon black nanoparticles during pregnancy persistently damages the cerebrovascular function in female mice

(2019) Yujia Zhang et al.   TOXICOLOGY

Selenium nanoparticles for targeted stroke therapy through modulation of inflammatory and metabolic signaling

(2019) Hamed Amani et al.   Scientific Reports

Neurotoxicity of ZnO nanoparticles and associated motor function deficits in mice

(2019) Atif Yaqub et al.   Applied Nanoscience

Protein-Capped Metal Nanoparticles Inhibit Tau Aggregation in Alzheimer’s Disease

(2019) Shweta Kishor Sonawane et al.   ACS Omega

Selenium Nanoparticles as an Efficient Nanomedicine for the Therapy of Huntington’s Disease

(2019) Wenshu Cong et al.   ACS Applied Materials & Interfaces

Behavior, protein, and dendritic changes after model traumatic brain injury and treatment with nanocoffee particles

(2019) Whitney A. Ratliff et al.   BMC NEUROSCIENCE

Enhancement of oral bioavailability of poorly water soluble carvedilol by chitosan nanoparticles: Optimization and pharmacokinetic study

(2019) Mayank Sharma et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Fabrication and evaluation of novel quercetin-conjugated Fe3O4–β-cyclodextrin nanoparticles for potential use in epilepsy disorder

(2019) Mona Hashemian et al.   International Journal of Nanomedicine

Recuperative effect of metformin loaded Polydopamine Nanoformulation promoting EZH2 mediated proteasomal degradation of phospho-α-Synuclein in Parkinson's disease model

(2019) Mo. Nadim Sardoiwala et al.   Nanomedicine-Nanotechnology Biology and Medicine

Solid lipid nanoparticles as a drug delivery system to across the blood-brain barrier

(2019) Haifei He et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

World Stroke Organization (WSO): Global Stroke Fact Sheet 2019

(2019) M Patrice Lindsay et al.   International Journal of Stroke

Gold Nanoparticles Treatment Reverses Brain Damage in Alzheimer’s Disease Model

(2019) Natalia dos Santos Tramontin et al.   MOLECULAR NEUROBIOLOGY

Neurotoxicity and biomarkers of zinc oxide nanoparticles in main functional brain regions and dopaminergic neurons

(2019) Huanliang Liu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Characterization of Brain Inflammation, Apoptosis, Hypoxia, Blood-Brain Barrier Integrity and Metabolism in Venezuelan Equine Encephalitis Virus (VEEV TC-83) Exposed Mice by In Vivo Positron Emission Tomography Imaging

(2019) Thomas M. Bocan et al.   Viruses-Basel

Amyloid-β peptides in cerebrospinal fluid of patients with dementia with Lewy bodies

(2019) Inger van Steenoven et al.   Alzheimers Research & Therapy

Efficacy of Cholesterol Nose-to-Brain Delivery for Brain Targeting in Huntington’s Disease

(2019) Alice Passoni et al.   ACS Chemical Neuroscience

Toxicity and effects of copper oxide nanoparticles on cognitive performances in rats

(2019) Souhir Ouni et al.   Archives of Environmental & Occupational Health

Enhancing the oral bioavailability of curcumin using solid lipid nanoparticles

(2019) Choongjin Ban et al.   FOOD CHEMISTRY

Enhancing myelin repair in experimental model of multiple sclerosis using immobilized chondroitinase ABC I on porous silicon nanoparticles

(2019) Safoura Rezaei et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Inflammasome and α-synuclein in Parkinson's disease: A cross-sectional study

(2019) Koustav Chatterjee et al.   JOURNAL OF NEUROIMMUNOLOGY

Biomimetic gold nanoparticles for its cytotoxicity and biocompatibility evidenced by fluorescence-based assays in cancer (MDA-MB-231) and non-cancerous (HEK-293) cells

(2019) Samynathan Jeyarani et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Trace elements profile in the blood of Huntington’ disease patients

(2019) Stefania Squadrone et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Early and rapid detection of UCHL1 in the serum of brain-trauma patients: a novel gold nanoparticle-based method for diagnosing the severity of brain injury

(2018) Gyaninder Pal Singh et al.   ANALYST

Ceria Nanoparticle Systems for Selective Scavenging of Mitochondrial, Intracellular, and Extracellular Reactive Oxygen Species in Parkinson's Disease

(2018) Hyek Jin Kwon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biodegradable PEG-poly(ω-pentadecalactone- co - p -dioxanone) nanoparticles for enhanced and sustained drug delivery to treat brain tumors

(2018) Evan M. Chen et al.   BIOMATERIALS

H1/pHGFK1 nanoparticles exert anti-tumoural and radiosensitising effects by inhibition of MET in glioblastoma

(2018) Wenyan Zhang et al.   BRITISH JOURNAL OF CANCER

The Combined Effects of ω -3 Fatty Acids and Nano-Curcumin Supplementation on Intercellular Adhesion Molecule-1 (ICAM-1) Gene Expression and Serum Levels in Migraine Patients

(2018) Neda Soveyd et al.   CNS & Neurological Disorders-Drug Targets

Solid lipid nanoparticles for delivery of andrographolide across the blood-brain barrier: in vitro and in vivo evaluation

(2018) Giulia Graverini et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

In Vivo MRI of Functionalized Iron Oxide Nanoparticles for Brain Inflammation

(2018) Tang Tang et al.   Contrast Media & Molecular Imaging

Using microfluidic platforms to develop CNS-targeted polymeric nanoparticles for HIV therapy

(2018) Cláudia Martins et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Piperine-loaded chitosan-STPP nanoparticles reduce neuronal loss and astrocytes activation in chemical kindling model of epilepsy

(2018) Diana Anissian et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Hesperetin and it nanocrystals ameliorate social behavior deficits and oxido-inflammatory stress in rat model of autism

(2018) Rashin Khalaj et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Intranasal delivery of Huperzine A to the brain using lactoferrin-conjugated N-trimethylated chitosan surface-modified PLGA nanoparticles for treatment of Alzheimer’s disease

(2018) Qingqing Meng et al.   International Journal of Nanomedicine

Nanoparticle-based delivery of carbamazepine: A promising approach for the treatment of refractory epilepsy

(2018) Anna Zybina et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Synthesis and biological imaging of cross-linked fluorescent polymeric nanoparticles with aggregation-induced emission characteristics based on the combination of RAFT polymerization and the Biginelli reaction

(2018) Jiande Dong et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Estimating the global incidence of traumatic brain injury

(2018) Michael C. Dewan et al.   JOURNAL OF NEUROSURGERY

Thymoquinone loaded solid lipid nanoparticles counteracts 3-Nitropropionic acid induced motor impairments and neuroinflammation in rat model of Huntington’s disease

(2018) Surekha Ramachandran et al.   METABOLIC BRAIN DISEASE

Improved neuroprotective effect of resveratrol nanoparticles as evinced by abrogation of rotenone-induced behavioral deficits and oxidative and mitochondrial dysfunctions in rat model of Parkinson’s disease

(2018) Suresh Palle et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Therapeutic nanoparticles penetrate leaves and deliver nutrients to agricultural crops

(2018) Avishai Karny et al.   Scientific Reports

Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles

(2018) Kasper Bendix Johnsen et al.   Theranostics

Convection-Enhanced Delivery of Polymeric Nanoparticles Encapsulating Chemotherapy in Canines with Spontaneous Supratentorial Tumors

(2018) Jacob S. Young et al.   World Neurosurgery

Comparative Evaluation of Prosopis cineraria (L.) Druce and Its ZnO Nanoparticles on Scopolamine Induced Amnesia

(2018) Ekta Yadav et al.   Frontiers in Pharmacology

Thrombin-Responsive, Brain-Targeting Nanoparticles for Improved Stroke Therapy

(2018) Xing Guo et al.   ACS Nano

A Novel Magnetic Nanoparticle for Early Detection of Amyloid Plaques in Alzheimer's Disease

(2018) Jiaqi Zeng et al.   ARCHIVES OF MEDICAL RESEARCH

Upregulation of klotho and erythropoietin contributes to the neuroprotection induced by curcumin-loaded nanoparticles in experimental model of chronic epilepsy

(2018) Sahar Rostami Mansoor et al.   BRAIN RESEARCH BULLETIN

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Amyotrophic Lateral Sclerosis and Oxidative Stress: a Double-Blind Therapeutic Trial After Curcumin Supplementation

(2018) Lucia Chico et al.   CNS & Neurological Disorders-Drug Targets

α-synuclein expression from a single copy transgene increases sensitivity to stress and accelerates neuronal loss in genetic models of Parkinson's disease

(2018) Jason F. Cooper et al.   EXPERIMENTAL NEUROLOGY

Pharmacokinetics and pharmacodynamics of intranasally administered selegiline nanoparticles with improved brain delivery in Parkinson's disease

(2018) Vinay Sridhar et al.   Nanomedicine-Nanotechnology Biology and Medicine

Lipid-Coated Mesoporous Silica Nanoparticles for the Delivery of the ML336 Antiviral to Inhibit Encephalitic Alphavirus Infection

(2018) Annette E. LaBauve et al.   Scientific Reports

Prenatal exposure to TiO2 nanoparticles in mice causes behavioral deficits with relevance to autism spectrum disorder and beyond

(2018) Tina Notter et al.   Translational Psychiatry

Rare-Earth-Doped Nanoparticles for Short-Wave Infrared Fluorescence Bioimaging and Molecular Targeting of αVβ3-Expressing Tumors

(2018) Dominik Jan Naczynski et al.   Molecular Imaging

Biodegradable Nanoparticles Containing Mechanism Based Peptide Inhibitors Reduce Polyglutamine Aggregation in Cell Models and Alleviate Motor Symptoms in a Drosophila Model of Huntington’s Disease

(2018) Abhayraj S. Joshi et al.   ACS Chemical Neuroscience

Brain Delivery of Curcumin Using Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Preparation, Optimization, and Pharmacokinetic Evaluation

(2018) Soroor Sadegh Malvajerd et al.   ACS Chemical Neuroscience

Predictive value of early MRI findings on neurocognitive and psychiatric outcomes in patients with severe traumatic brain injury

(2018) Nasser M. Aldossary et al.   JOURNAL OF AFFECTIVE DISORDERS

Toxicity of iron oxide nanoparticles: Size and coating effects

(2018) Maxim A. Abakumov et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Mild cognitive impairment in long-term brain tumor survivors following brain irradiation

(2018) Christina K. Cramer et al.   JOURNAL OF NEURO-ONCOLOGY

Combined intracavitary thermotherapy with iron oxide nanoparticles and radiotherapy as local treatment modality in recurrent glioblastoma patients

(2018) Oliver Grauer et al.   JOURNAL OF NEURO-ONCOLOGY

TiO2 Nanoparticles Catalyze Oxidation of Huntingtin Exon 1-Derived Peptides Impeding Aggregation: A Quantitative NMR Study of Binding and Kinetics

(2018) Alberto Ceccon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2018) E. Ray Dorsey et al.   LANCET NEUROLOGY

Prolonged Exposure to Silver Nanoparticles Results in Oxidative Stress in Cerebral Myelin

(2018) Beata Dąbrowska-Bouta et al.   NEUROTOXICITY RESEARCH

Nose to Brain Delivery of Galantamine Loaded Nanoparticles: In-vivo Pharmacodynamic and Biochemical Study in Mice

(2018) Sunena et al.   Current Drug Delivery

Listeria monocytogenes Infection of the Brain

(2018) Pallab Ghosh et al.   Jove-Journal of Visualized Experiments

Nicotinamide loaded functionalized solid lipid nanoparticles improves cognition in Alzheimer’s disease animal model by reducing Tau hyperphosphorylation

(2018) Molood Alsadat Vakilinezhad et al.   DARU-Journal of Pharmaceutical Sciences

The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients

(2017) Mina Abdolahi et al.   IMMUNOGENETICS

Surface-modified gatifloxacin nanoparticles with potential for treating central nervous system tuberculosis

(2017) PATRICIA MARCIANES et al.   International Journal of Nanomedicine

Injection of SDF-1 loaded nanoparticles following traumatic brain injury stimulates neural stem cell recruitment

(2017) Laura N. Zamproni et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Targeted delivery of glucocorticoids to macrophages in a mouse model of multiple sclerosis using inorganic-organic hybrid nanoparticles

(2017) Elena Montes-Cobos et al.   JOURNAL OF CONTROLLED RELEASE

Comprehensive Insights into the Multi-Antioxidative Mechanisms of Melanin Nanoparticles and Their Application To Protect Brain from Injury in Ischemic Stroke

(2017) Yanlan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2017) Valery L Feigin et al.   LANCET NEUROLOGY

The size-effect of gold nanoparticles and nanoclusters in the inhibition of amyloid-β fibrillation

(2017) Guanbin Gao et al.   Nanoscale

The evolving landscape of drug products containing nanomaterials in the United States

(2017) Sheetal R. D'Mello et al.   Nature Nanotechnology

Cerium oxide nanoparticles could ameliorate behavioral and neurochemical impairments in 6-hydroxydopamine induced Parkinson's disease in rats

(2017) Maha A. Hegazy et al.   NEUROCHEMISTRY INTERNATIONAL

Amyotrophic Lateral Sclerosis

(2017) Robert H. Brown et al.   NEW ENGLAND JOURNAL OF MEDICINE

Solid state characterization, solid dispersions, solubility enhancement, drug dissolution and drug release

(2017) Raid Alany   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

Curcumin-loaded chitosan-alginate-STPP nanoparticles ameliorate memory deficits and reduce glial activation in pentylenetetrazol-induced kindling model of epilepsy

(2017) Mona Hashemian et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Inhibition by Multifunctional Magnetic Nanoparticles Loaded with Alpha-Synuclein RNAi Plasmid in a Parkinson's Disease Model

(2017) Shuiqin Niu et al.   Theranostics

Self-Assembly of Gold Nanoparticles Shows Microenvironment-Mediated Dynamic Switching and Enhanced Brain Tumor Targeting

(2017) Qishuai Feng et al.   Theranostics

Influence of gold nanoparticle surface chemistry and diameter upon Alzheimer’s disease amyloid-β protein aggregation

(2017) Kelly A. Moore et al.   Journal of Biological Engineering

Reduced Levels of Amyloid-β-Binding Proteins in Cerebrospinal Fluid from Alzheimer's Disease Patients

(2017) Sara F. Hansson et al.   JOURNAL OF ALZHEIMERS DISEASE

Midlife Coffee and Tea Drinking and the Risk of Late-Life Dementia: A Population-Based CAIDE Study

(2017) Marjo H. Eskelinen et al.   JOURNAL OF ALZHEIMERS DISEASE

Blood–Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy

(2016) Tingting Lin et al.   ACS Nano

2016 Alzheimer's disease facts and figures

(2016)   Alzheimers & Dementia

Iron Chelation Nanoparticles with Delayed Saturation as an Effective Therapy for Parkinson Disease

(2016) Nan Wang et al.   BIOMACROMOLECULES

Pluronic P85-coated poly(butylcyanoacrylate) nanoparticles overcome phenytoin resistance in P-glycoprotein overexpressing rats with lithium-pilocarpine-induced chronic temporal lobe epilepsy

(2016) Ziyan Fang et al.   BIOMATERIALS

Edible ginger-derived nanoparticles: A novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer

(2016) Mingzhen Zhang et al.   BIOMATERIALS

Synthesis and characterization of retrograded starch nanoparticles through homogenization and miniemulsion cross-linking

(2016) Yongbo Ding et al.   CARBOHYDRATE POLYMERS

Brain-derived neurotrophic factor delivered to the brain using poly (lactide-co-glycolide) nanoparticles improves neurological and cognitive outcome in mice with traumatic brain injury

(2016) Igor Khalin et al.   DRUG DELIVERY

Epigenetic changes in T-cell and monocyte signatures and production of neurotoxic cytokines in ALS patients

(2016) Larry Lam et al.   FASEB JOURNAL

Silver nanoparticles outperform gold nanoparticles in radiosensitizing U251 cells in vitro and in an intracranial mouse model of glioma

(2016) Pei Dang Liu et al.   International Journal of Nanomedicine

MicroRNA-124 loaded nanoparticles enhance brain repair in Parkinson's disease

(2016) C. Saraiva et al.   JOURNAL OF CONTROLLED RELEASE

Cerium Oxide Nanoparticles Improve Outcome After In Vitro and In Vivo Mild Traumatic Brain Injury

(2016) Zachary S. Bailey et al.   JOURNAL OF NEUROTRAUMA

Correlation of Oxidative Stress Parameters and Inflammatory Markers in Ischemic Stroke Patients

(2016) Khouloud Chehaibi et al.   Journal of Stroke & Cerebrovascular Diseases

PEGylation of Reduced Graphene Oxide Induces Toxicity in Cells of the Blood–Brain Barrier: An in Vitro and in Vivo Study

(2016) Monique Culturato Padilha Mendonça et al.   MOLECULAR PHARMACEUTICS

Cerium oxide nanoparticles with antioxidant properties ameliorate strength and prolong life in mouse model of amyotrophic lateral sclerosis

(2016) William DeCoteau et al.   Nanomedicine-Nanotechnology Biology and Medicine

Nerolidol-loaded nanospheres prevent behavioral impairment via ameliorating Na+, K+-ATPase and AChE activities as well as reducing oxidative stress in the brain of Trypanosoma evansi-infected mice

(2016) Matheus D. Baldissera et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The Levels of Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 During the First Week After a Traumatic Brain Injury

(2016) Jussi P. Posti et al.   NEUROSURGERY

Correlation of Oxidative Stress Parameters and Inflammatory Markers in Ischemic Stroke Patients

(2016) Khouloud Chehaibi et al.   Journal of Stroke & Cerebrovascular Diseases

General and programmable synthesis of hybrid liposome/metal nanoparticles

(2016) J.-H. Lee et al.   Science Advances

Polymeric Nanoparticles for Nonviral Gene Therapy Extend Brain Tumor Survival in Vivo

(2015) Antonella Mangraviti et al.   ACS Nano

Curcumin-conjugated magnetic nanoparticles for detecting amyloid plaques in Alzheimer's disease mice using magnetic resonance imaging (MRI)

(2015) Kwok Kin Cheng et al.   BIOMATERIALS

Astrocyte uncoupling as a cause of human temporal lobe epilepsy

(2015) Peter Bedner et al.   BRAIN

Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice

(2015) M. Valenza et al.   EMBO Molecular Medicine

Anti-transferrin receptor-modified amphotericin B-loaded PLA–PEG nanoparticles cure Candidal meningitis and reduce drug toxicity

(2015) Xiaolong Tang et al.   International Journal of Nanomedicine

Analysis of titanium dioxide and zinc oxide nanoparticles in cosmetics

(2015) Pei-Jia Lu et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Synthesis and Characterization of Hydroxyapatite/Fullerenol Nanocomposites

(2015) Aleksandar Djordjevic et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Radiosensitivity enhancement of radioresistant glioblastoma by epidermal growth factor receptor antibody-conjugated iron-oxide nanoparticles

(2015) Alexandros Bouras et al.   JOURNAL OF NEURO-ONCOLOGY

PLGA Nanoparticles Loaded Cerebrolysin: Studies on Their Preparation and Investigation of the Effect of Storage and Serum Stability with Reference to Traumatic Brain Injury

(2015) Barbara Ruozi et al.   MOLECULAR NEUROBIOLOGY

Thioridazine in PLGA nanoparticles reduces toxicity and improves rifampicin therapy against mycobacterial infection in zebrafish

(2015) Carina Beatrice Vibe et al.   Nanotoxicology

Curcumin attenuates inflammatory response and cognitive deficits in experimental model of chronic epilepsy

(2015) Harpreet Kaur et al.   NEUROCHEMISTRY INTERNATIONAL

Impact of gold nanoparticles on brain of mice infected with Schistosoma mansoni

(2015) Mohamed A. Dkhil et al.   PARASITOLOGY RESEARCH

Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells

(2015) L M A Oliveira et al.   Cell Death & Disease

Brain-Penetrating Nanoparticles Improve Paclitaxel Efficacy in Malignant Glioma Following Local Administration

(2014) Elizabeth Nance et al.   ACS Nano

ILAE Official Report: A practical clinical definition of epilepsy

(2014) Robert S. Fisher et al.   EPILEPSIA

Self-assembled peptide nanoparticles as tumor microenvironment activatable probes for tumor targeting and imaging

(2014) Ying Zhao et al.   JOURNAL OF CONTROLLED RELEASE

Altered selenium status in Huntington's disease: Neuroprotection by selenite in the N171-82Q mouse model

(2014) Zhen Lu et al.   NEUROBIOLOGY OF DISEASE

Glycogen Synthase Kinase-3 Regulates Production of Amyloid-βPeptides and Tau Phosphorylation in Diabetic Rat Brain

(2014) Zhong-Sen Qu et al.   TheScientificWorldJOURNAL

Inhibiting drug efflux transporters improves efficacy of ALS therapeutics

(2014) Michael R. Jablonski et al.   Annals of Clinical and Translational Neurology

Nanoparticle mediated brain targeted delivery of gallic acid:in vivobehavioral and biochemical studies for protection against scopolamine-induced amnesia

(2013) Kalpana Nagpal et al.   DRUG DELIVERY

A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease

(2013) Han-Yun Hsiao et al.   HUMAN MOLECULAR GENETICS

Optimization of brain targeted chitosan nanoparticles of Rivastigmine for improved efficacy and safety

(2013) Kalpana Nagpal et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Plasma 24S-hydroxycholesterol correlation with markers of Huntington disease progression

(2013) Valerio Leoni et al.   NEUROBIOLOGY OF DISEASE

Selective Targeting of Brain Tumors with Gold Nanoparticle-Induced Radiosensitization

(2013) Daniel Y. Joh et al.   PLoS One

Amyloid-beta oligomerization in Alzheimer dementia versus high-pathology controls

(2012) Thomas J. Esparza et al.   ANNALS OF NEUROLOGY

Temporary Disruption of the Blood-Brain Barrier by Use of Ultrasound and Microbubbles: Safety and Efficacy Evaluation in Rhesus Macaques

(2012) N. McDannold et al.   CANCER RESEARCH

Histone Deacetylase-1 (HDAC1) Is a Molecular Switch between Neuronal Survival and Death

(2012) Farah H. Bardai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Drug Transport across the Blood–Brain Barrier

(2012) William M Pardridge   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Oxidative stress and inflammation biomarkers in the blood of patients with Huntington’s disease

(2012) Fernando Sánchez-López et al.   NEUROLOGICAL RESEARCH

Negatively Charged Gold Nanoparticles Inhibit Alzheimer's Amyloid-β Fibrillization, Induce Fibril Dissociation, and Mitigate Neurotoxicity

(2012) Yi-Hung Liao et al.   Small

Brain infections

(2012) J.-L. Sarrazin et al.   Diagnostic and Interventional Imaging

Green synthesis of biogenic metal nanoparticles by terrestrial and aquatic phototrophic and heterotrophic eukaryotes and biocompatible agents

(2011) Kannan Badri Narayanan et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Kinetic Targeting of pegylated liposomal Doxorubicin: a new Approach to Reduce Toxicity during Chemotherapy (CARL-trial)

(2011) Jürgen Eckes et al.   BMC CANCER

Blood–brain barrier P-glycoprotein function in Alzheimer's disease

(2011) Daniëlle M. E. van Assema et al.   BRAIN

Refractory Epilepsy Associated With Microglial Activation

(2011) Souhel Najjar et al.   NEUROLOGIST

Inflammatory Cortical Demyelination in Early Multiple Sclerosis

(2011) Claudia F. Lucchinetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rapid astrocyte and microglial activation following pilocarpine-induced seizures in rats

(2010) Lee A. Shapiro et al.   EPILEPSIA

Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme

(2010) Klaus Maier-Hauff et al.   JOURNAL OF NEURO-ONCOLOGY

HDAC6 Regulates Mitochondrial Transport in Hippocampal Neurons

(2010) Sigeng Chen et al.   PLoS One

Low-grade systemic inflammation in patients with amyotrophic lateral sclerosis

(2009) D. Keizman et al.   ACTA NEUROLOGICA SCANDINAVICA

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Endogenous Melatonin Increases in Cerebrospinal Fluid of Patients after Severe Traumatic Brain Injury and Correlates with Oxidative Stress and Metabolic Disarray

(2008) Marc A Seifman et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau

(2008) K. N. Green et al.   JOURNAL OF NEUROSCIENCE

Efficacy of Silver Nanoparticles-Impregnated External Ventricular Drain Catheters in Patients with Acute Occlusive Hydrocephalus

(2008) Peter Lackner et al.   Neurocritical Care

Oxidative Stress and Matrix Metalloproteinase-9 in Acute Ischemic Stroke

(2007) Peter J. Kelly et al.   STROKE