Transport of PEGylated-PLA nanoparticles across a blood brain barrier model, entry into neuronal cells and in vivo brain bioavailability

Live Tracking of Inter-organ Communication by Endogenous Exosomes In Vivo

(2019) Frederik J. Verweij et al.   DEVELOPMENTAL CELL

Extracellular Vesicles: Catching the Light in Zebrafish

(2019) Frederik J. Verweij et al.   TRENDS IN CELL BIOLOGY

Directing Nanoparticle Biodistribution through Evasion and Exploitation of Stab2-Dependent Nanoparticle Uptake

(2018) Frederick Campbell et al.   ACS Nano

Uptake, tissue distribution, and toxicity of polystyrene nanoparticles in developing zebrafish ( Danio rerio )

(2018) Jordan A. Pitt et al.   AQUATIC TOXICOLOGY

Quantification of kinetic rate constants for transcytosis of polymeric nanoparticle through blood-brain barrier

(2018) Aminul Islam Khan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Length of surface PEG modulates nanocarrier transcytosis across brain vascular endothelial cells

(2018) Soudeh F. Tehrani et al.   Nanomedicine-Nanotechnology Biology and Medicine

Comprehensive study of the drug delivery properties of poly( l -lactide)-poly(ethylene glycol) nanoparticles in rats and tumor-bearing mice

(2017) Vladimir Shalgunov et al.   JOURNAL OF CONTROLLED RELEASE

New potential strategies for Alzheimer's disease prevention: pegylated biodegradable dexibuprofen nanospheres administration to APPswe/PS1dE9

(2017) Elena Sánchez-López et al.   Nanomedicine-Nanotechnology Biology and Medicine

Systematic investigation on the intracellular trafficking network of polymeric nanoparticles

(2017) Jinxie Zhang et al.   Nanoscale

Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis

(2017) Benjamin J. Andreone et al.   NEURON

Biological Identity of Nanoparticles In Vivo : Clinical Implications of the Protein Corona

(2017) Giulio Caracciolo et al.   TRENDS IN BIOTECHNOLOGY

Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics

(2017) Nicolas Bertrand et al.   Nature Communications

Intracellular Accumulation of Gold Nanoparticles Leads to Inhibition of Macropinocytosis to Reduce the Endoplasmic Reticulum Stress

(2017) Nuray Gunduz et al.   Scientific Reports

Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma

(2017) Kasper Bendix Johnsen et al.   Scientific Reports

Into rather unexplored terrain-transcellular transport across the blood-brain barrier

(2016) Marijke De Bock et al.   GLIA

‘Stealth’ nanoparticles evade neural immune cells but also evade major brain cell populations: Implications for PEG-based neurotherapeutics

(2016) Stuart I. Jenkins et al.   JOURNAL OF CONTROLLED RELEASE

Effect of the Polymer Architecture on the Structural and Biophysical Properties of PEG–PLA Nanoparticles

(2015) Jean-Michel Rabanel et al.   ACS Applied Materials & Interfaces

The interaction of carbon nanotubes with an in vitro blood-brain barrier model and mouse brain in vivo

(2015) Houmam Kafa et al.   BIOMATERIALS

Effect of polymer architecture on curcumin encapsulation and release from PEGylated polymer nanoparticles: Toward a drug delivery nano-platform to the CNS

(2015) Jean-Michel Rabanel et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Fate of cerium dioxide nanoparticles in endothelial cells: exocytosis

(2015) Claudia Strobel et al.   JOURNAL OF NANOPARTICLE RESEARCH

Neuronal Uptake and Neuroprotective Properties of Curcumin-Loaded Nanoparticles on SK-N-SH Cell Line: Role of Poly(lactide-co-glycolide) Polymeric Matrix Composition

(2015) Ghislain Djiokeng Paka et al.   MOLECULAR PHARMACEUTICS

Increased brain uptake of targeted nanoparticles by adding an acid-cleavable linkage between transferrin and the nanoparticle core

(2015) Andrew J. Clark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging Approach to Mechanistic Study of Nanoparticle Interactions with the Blood–Brain Barrier

(2014) Mattia Bramini et al.   ACS Nano

Assessment of PEG on polymeric particles surface, a key step in drug carrier translation

(2014) Jean-Michel Rabanel et al.   JOURNAL OF CONTROLLED RELEASE

Drug delivery to the central nervous system by polymeric nanoparticles: What do we know?

(2013) Jörg Kreuter   ADVANCED DRUG DELIVERY REVIEWS

Paracellular Barrier and Tight Junction Protein Expression in the Immortalized Brain Endothelial Cell Lines bEND.3, bEND.5 and Mouse Brain Endothelial Cell 4

(2013) Takuya Watanabe et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Acetylcholinesterase Inhibitors: Pharmacology and Toxicology

(2013) Mirjana B. Colovic et al.   Current Neuropharmacology

Epstein-Barr Virus Transcytosis through Polarized Oral Epithelial Cells

(2013) S. M. Tugizov et al.   JOURNAL OF VIROLOGY

Curcumin protects neuronal-like cells against acrolein by restoring Akt and redox signaling pathways

(2013) Sihem Doggui et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Nanoparticle accumulation and transcytosis in brain endothelial cell layers

(2013) Dong Ye et al.   Nanoscale

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

Functional Characterisation of the Maturation of the Blood-Brain Barrier in Larval Zebrafish

(2013) Angeleen Fleming et al.   PLoS One

Endocytosis at the nanoscale

(2012) Irene Canton et al.   CHEMICAL SOCIETY REVIEWS

Drug-Loaded Nanocarriers: Passive Targeting and Crossing of Biological Barriers

(2012) J. M. Rabanel et al.   CURRENT MEDICINAL CHEMISTRY

Membrane configuration optimization for a murine in vitro blood–brain barrier model

(2012) Diane M. Wuest et al.   JOURNAL OF NEUROSCIENCE METHODS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

A Dense Poly(Ethylene Glycol) Coating Improves Penetration of Large Polymeric Nanoparticles Within Brain Tissue

(2012) E. A. Nance et al.   Science Translational Medicine

Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

(2012) J. Hrkach et al.   Science Translational Medicine

Internal benchmarking of a human blood–brain barrier cell model for screening of nanoparticle uptake and transcytosis

(2011) Michelle Nic Ragnaill et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Delivery of nanoparticle-complexed drugs across the vascular endothelial barrier via caveolae

(2011) Zhenjia Wang et al.   IUBMB LIFE

Investigation of barrier characteristics in the hyaloid-retinal vessel of zebrafish

(2011) Jin Hyoung Kim et al.   JOURNAL OF NEUROSCIENCE RESEARCH

BSA Adsorption on Differently Charged Polystyrene Nanoparticles using Isothermal Titration Calorimetry and the Influence on Cellular Uptake

(2011) Grit Baier et al.   MACROMOLECULAR BIOSCIENCE

A Strategy for Control of “Random” Copolymerization of Lactide and Glycolide: Application to Synthesis of PEG-b-PLGA Block Polymers Having Narrow Dispersity

(2011) Haitao Qian et al.   MACROMOLECULES

Effects of Transport Inhibitors on the Cellular Uptake of Carboxylated Polystyrene Nanoparticles in Different Cell Lines

(2011) Tiago dos Santos et al.   PLoS One

Permeability of Endothelial and Astrocyte Cocultures: In Vitro Blood–Brain Barrier Models for Drug Delivery Studies

(2010) Guanglei Li et al.   ANNALS OF BIOMEDICAL ENGINEERING

Claudin-3 acts as a sealing component of the tight junction for ions of either charge and uncharged solutes

(2010) Susanne Milatz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

(2010) Mirkka Koivusalo et al.   JOURNAL OF CELL BIOLOGY

Surface Characteristics of Nanoparticles Determine Their Intracellular Fate in and Processing by Human Blood–Brain Barrier Endothelial Cells In Vitro

(2010) Julia V Georgieva et al.   MOLECULAR THERAPY

Nanocarriers’ entry into the cell: relevance to drug delivery

(2009) Hervé Hillaireau et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Different Changes in Protein and Phosphoprotein Levels Result from Serum Starvation of High-Grade Glioma and Adenocarcinoma Cell Lines

(2009) Victor A. Levin et al.   JOURNAL OF PROTEOME RESEARCH

The Use of Inhibitors to Study Endocytic Pathways of Gene Carriers: Optimization and Pitfalls

(2009) Dries Vercauteren et al.   MOLECULAR THERAPY

Mediating Tumor Targeting Efficiency of Nanoparticles Through Design

(2009) Steven D. Perrault et al.   NANO LETTERS

Defining Macropinocytosis

(2009) Markus C. Kerr et al.   TRAFFIC

Polyalkylcyanoacrylate nanoparticles for delivery of drugs across the blood-brain barrier

(2009) Karine Andrieux et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications

(2008) Elliott J Mufson et al.   Expert Review of Neurotherapeutics

Functional and developmental analysis of the blood–brain barrier in zebrafish

(2007) Jae-Yeon Jeong et al.   BRAIN RESEARCH BULLETIN