Reactive Oxygen Species Rewires Metabolic Activity in Acute Myeloid Leukemia

The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells

(2019) Biniam Adane et al.   Cell Reports

Reactive Oxygen Species Drive Proliferation in Acute Myeloid Leukemia via the Glycolytic Regulator PFKFB3

(2019) Andrew J. Robinson et al.   CANCER RESEARCH

Reactive oxygen species in haematopoiesis: leukaemic cells take a walk on the wild side

(2018) Rodrigo Prieto-Bermejo et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions

(2017) Amelie V. Guitart et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Role of Sphingosine-1-Phosphate and Ceramide-1-Phosphate in Inflammation and Cancer

(2017) Nitai C. Hait et al.   MEDIATORS OF INFLAMMATION

Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors

(2015) Anneleen Daemen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIF-1-mediated metabolic reprogramming reduces ROS levels and facilitates the metastatic colonization of cancers in lungs

(2014) Tao Zhao et al.   Scientific Reports

Nox Enzymes and New Thinking on Reactive Oxygen: A Double-Edged Sword Revisited

(2013) J. David Lambeth et al.   Annual Review of Pathology-Mechanisms of Disease

Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling

(2013) P. S. Hole et al.   BLOOD

Principles in Redox Signaling: From Chemistry to Functional Significance

(2012) Alberto Bindoli et al.   ANTIOXIDANTS & REDOX SIGNALING

A metabolic prosurvival role for PML in breast cancer

(2012) Arkaitz Carracedo et al.   JOURNAL OF CLINICAL INVESTIGATION

Do reactive oxygen species play a role in myeloid leukemias?

(2011) P. S. Hole et al.   BLOOD

Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress

(2011) K. Zaugg et al.   GENES & DEVELOPMENT

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

(2011) Ariel C. Bulua et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Involvement of Oxidative Stress in the Relapse of Acute Myeloid Leukemia

(2010) Fu-Ling Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Ras-induced reactive oxygen species promote growth factor-independent proliferation in human CD34+ hematopoietic progenitor cells

(2009) P. S. Hole et al.   BLOOD

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

(2009) Zachary T. Schafer et al.   NATURE

Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: implications for poor prognosis in AML

(2008) A. Sallmyr et al.   BLOOD

Classical Inhibitors of NOX NAD(P)H Oxidases Are Not Specific

(2008) Elisabetta Aldieri et al.   CURRENT DRUG METABOLISM