The Role of circRNAs in Human Papillomavirus (HPV)-Associated Cancers

Structure-Mediated RNA Decay by UPF1 and G3BP1

(2020) Joseph W. Fischer et al.   MOLECULAR CELL

Circular RNA cSMARCA5 regulates the progression of cervical cancer by acting as a microRNA‑432 sponge

(2020) Ping Huang et al.   Molecular Medicine Reports

Circular RNA expression profiling identifies specific circular RNAs in tongue squamous cell carcinoma

(2020) Tai Wei et al.   Molecular Medicine Reports

The Role of microRNAs, Long Non-coding RNAs, and Circular RNAs in Cervical Cancer

(2020) Maria Lina Tornesello et al.   Frontiers in Oncology

Circular RNA_0001742 has potential to predict advanced tumor stage and poor survival profiles in tongue squamous cell carcinoma management

(2020) Yuan Yao et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Functional and Clinical Impact of CircRNAs in Oral Cancer

(2020) Ion Cristóbal et al.   Cancers

A New World of Biomarkers and Therapeutics for Female Reproductive System and Breast Cancers: Circular RNAs

(2020) Anh M. Tran et al.   Frontiers in Cell and Developmental Biology

Circular RNA profiling in plasma exosomes from patients with gastric cancer

(2020) Min Rao et al.   Oncology Letters

Upregulation of circ_0000199 in circulating exosomes is associated with survival outcome in OSCC

(2020) Yanwei Luo et al.   Scientific Reports

Circular RNAs: New Epigenetic Signatures in Viral Infections

(2020) Javid Sadri Nahand et al.   Frontiers in Microbiology

The Expression, Functions and Mechanisms of Circular RNAs in Gynecological Cancers

(2020) Peixin Dong et al.   Cancers

Biosynthesis of Circular RNA ciRS-7/CDR1as Is Mediated by Mammalian-wide Interspersed Repeats

(2020) Rei Yoshimoto et al.   iScience

The Significance of Circular RNA DDX17 in Prostate Cancer

(2020) Qi Lin et al.   Biomed Research International

Emerging Function and Clinical Significance of Exosomal circRNAs in Cancer

(2020) Man Wang et al.   Molecular Therapy-Nucleic Acids

CircRNA hsa_circRNA_101996 increases cervical cancer proliferation and invasion through activating TPX2 expression by restraining miR-8075

(2019) Tiefang Song et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The novel roles of circRNAs in human cancer

(2019) Qingfeng Shang et al.   Molecular Cancer

Expression profiles and potential functions of circular RNAs in extracellular vesicles isolated from radioresistant glioma cells

(2019) Mengjie Zhao et al.   ONCOLOGY REPORTS

Insights into the biogenesis and potential functions of exonic circular RNA

(2019) Chikako Ragan et al.   Scientific Reports

Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex

(2019) Ok Hyun Park et al.   MOLECULAR CELL

Circular RNA hsa_circ_0055538 regulates the malignant biological behavior of oral squamous cell carcinoma through the p53/Bcl-2/caspase signaling pathway

(2019) Wen Su et al.   Journal of Translational Medicine

Circular RNA hsa_circ_0007059 indicates prognosis and influences malignant behavior via AKT/mTOR in oral squamous cell carcinoma

(2019) Wen Su et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hsa_circ_0001742 promotes tongue squamous cell carcinoma progression via modulating miR-634 expression

(2019) Beibei Shao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Circular RNAs in gynecological disease: promising biomarkers and diagnostic targets

(2019) Jie Huang et al.   BIOSCIENCE REPORTS

Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity

(2019) Chu-Xiao Liu et al.   CELL

133 Translation and transforming activity of a circular RNA from human papillomavirus

(2019) J. Zhao et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Expression of circular RNAs in gynecological tumors

(2019) Kangsheng Liu et al.   MEDICINE

Circular RNA hsa_circ_009755 downregulation correlates with clinicopathology in oral squamous cell carcinoma

(2019) Zihong Wang et al.   OncoTargets and Therapy

hsa_circ_0000745 promotes cervical cancer by increasing cell proliferation, migration, and invasion

(2019) Jun Jiao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus

(2019) Jiawei Zhao et al.   Nature Communications

Circular RNAs in Cancer

(2019) Duc-Hiep Bach et al.   Molecular Therapy-Nucleic Acids

The RNA-binding protein RBM3 promotes cell proliferation in hepatocellular carcinoma by regulating circular RNA SCD-circRNA 2 production

(2019) Wei Dong et al.   EBioMedicine

The Landscape of Circular RNA Expression in the Human Brain

(2019) Akira Gokool et al.   BIOLOGICAL PSYCHIATRY

Splicing factor derived circular RNA circUHRF1 accelerates oral squamous cell carcinoma tumorigenesis via feedback loop

(2019) Wei Zhao et al.   CELL DEATH AND DIFFERENTIATION

Recent Progress on Circular RNA Research in Acute Myeloid Leukemia

(2019) Muhammad Jamal et al.   Frontiers in Oncology

Genome-Wide Analysis of Circular RNAs Mediated ceRNA Regulation in Porcine Embryonic Muscle Development

(2019) Linjun Hong et al.   Frontiers in Cell and Developmental Biology

Circular RNAs and gastrointestinal cancers: Epigenetic regulators with a prognostic and therapeutic role

(2019) Parisa Naeli et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Circular RNA circSLC26A4 Accelerates Cervical Cancer Progression via miR-1287-5p/HOXA7 Axis

(2019) Fei Ji et al.   Molecular Therapy-Nucleic Acids

Circular RNA hsa_circ_0023404 exerts an oncogenic role in cervical cancer through regulating miR-136/TFCP2/YAP pathway

(2018) Jianhua Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Increased circular RNA hsa_circ_0012673 acts as a sponge of miR-22 to promote lung adenocarcinoma proliferation

(2018) Xiyong Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Salivary Circular RNAs Hsa_Circ_0001874 and Hsa_Circ_0001971 as Novel Biomarkers for the Diagnosis of Oral Squamous Cell Carcinoma

(2018) Si-Yu Zhao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

CircRNA8924 Promotes Cervical Cancer Cell Proliferation, Migration and Invasion by Competitively Binding to MiR-518d-5p /519-5p Family and Modulating the Expression of CBX8

(2018) Jiamei Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Deep RNA Sequencing Reveals a Repertoire of Human Fibroblast Circular RNAs Associated with Cellular Responses to Herpes Simplex Virus 1 Infection

(2018) Jiandong Shi et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Post-Transcriptional Regulation of Anti-Apoptotic BCL2 Family Members

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human papillomavirus types from infection to cancer in the anus, according to sex and HIV status: a systematic review and meta-analysis

(2018) Chunqing Lin et al.   LANCET INFECTIOUS DISEASES

Circular RNAs function as ceRNAs to regulate and control human cancer progression

(2018) Yaxian Zhong et al.   Molecular Cancer

Circular RNA and its mechanisms in disease: From the bench to the clinic

(2018) Bing Han et al.   PHARMACOLOGY & THERAPEUTICS

Genome-Wide Identification of circRNAs in Pathogenic Basidiomycetous Yeast Cryptococcus neoformans Suggests Conserved circRNA Host Genes over Kingdoms

(2018) Liang Huo et al.   Genes

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Hsa_circ_0008309 May Be a Potential Biomarker for Oral Squamous Cell Carcinoma

(2018) Bowen Li et al.   DISEASE MARKERS

Circular RNAs: Promising Biomarkers for Human Diseases

(2018) Zhongrong Zhang et al.   EBioMedicine

Increased AURKA promotes cell proliferation and predicts poor prognosis in bladder cancer

(2018) Mengjie Guo et al.   BMC Systems Biology

CircPCNXL2 sponges miR-153 to promote the proliferation and invasion of renal cancer cells through upregulating ZEB2

(2018) Bisheng Zhou et al.   CELL CYCLE

Cancer of the vagina

(2018) Tracey S. Adams et al.   INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS

Circular RNA hsa_circ_0000263 participates in cervical cancer development by regulating target gene of miR-150-5p

(2018) Hongning Cai et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Discovery of Kaposi’s sarcoma herpesvirus-encoded circular RNAs and a human antiviral circular RNA

(2018) Takanobu Tagawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The roles of circular RNAs in human development and diseases

(2018) Eric Chun Shen Lee et al.   BIOMEDICINE & PHARMACOTHERAPY

hsa_circ_0013958: a circular RNA and potential novel biomarker for lung adenocarcinoma

(2017) Xiaoli Zhu et al.   FEBS Journal

The emerging role of circular RNAs in transcriptome regulation

(2017) S. Huang et al.   GENOMICS

Geographic heterogeneity in the prevalence of human papillomavirus in head and neck cancer

(2017) Devasena Anantharaman et al.   INTERNATIONAL JOURNAL OF CANCER

Worldwide burden of cancer attributable to HPV by site, country and HPV type

(2017) Catherine de Martel et al.   INTERNATIONAL JOURNAL OF CANCER

Circular RNAs in cancer: an emerging key player

(2017) Yeping Dong et al.   Journal of Hematology & Oncology

Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis

(2017) Yibing Yang et al.   JNCI-Journal of the National Cancer Institute

CircRNA: functions and properties of a novel potential biomarker for cancer

(2017) Shujuan Meng et al.   Molecular Cancer

Circular RNAs in human cancer

(2017) Yumin Wang et al.   Molecular Cancer

Translation of CircRNAs

(2017) Nagarjuna Reddy Pamudurti et al.   MOLECULAR CELL

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

(2017) Ivano Legnini et al.   MOLECULAR CELL

Circular RNAs in cancer: opportunities and challenges in the field

(2017) L S Kristensen et al.   ONCOGENE

Engineering and expressing circular RNAs via tRNA splicing

(2017) John J. Noto et al.   RNA Biology

Pathology of Anal Cancer

(2017) Paulo M. Hoff et al.   Surgical Oncology Clinics of North America

Circ-104916 is downregulated in gastric cancer and suppresses migration and invasion of gastric cancer cells

(2017) Jin Li et al.   OncoTargets and Therapy

Modulation of microRNA-mRNA Target Pairs by Human Papillomavirus 16 Oncoproteins

(2017) Mallory E. Harden et al.   mBio

Screening of up‑ and downregulation of circRNAs in HBV‑related hepatocellular carcinoma by microarray

(2017) Shichang Cui et al.   Oncology Letters

Ataxin-1 is involved in tumorigenesis of cervical cancer cells via the EGFR–RAS–MAPK signaling pathway

(2017) A-ram Kang et al.   Oncotarget

Ataxin-1 regulates epithelial–mesenchymal transition of cervical cancer cells

(2017) A-ram Kang et al.   Oncotarget

Polymorphisms and expression pattern of circular RNA circ-ITCH contributes to the carcinogenesis of hepatocellular carcinoma

(2017) Wenzhi Guo et al.   Oncotarget

Circular RNA expression profiles reveal that hsa_circ_0018289 is up-regulated in cervical cancer and promotes the tumorigenesis

(2017) Ya-Li Gao et al.   Oncotarget

Hsa_circ_0005986 inhibits carcinogenesis by acting as a miR-129-5p sponge and is used as a novel biomarker for hepatocellular carcinoma

(2017) Liyun Fu et al.   Oncotarget

Screening differential circular RNA expression profiles reveals hsa_circ_0004018 is associated with hepatocellular carcinoma

(2017) Liyun Fu et al.   Oncotarget

Identifying and Characterizing circRNA-Protein Interaction

(2017) William W Du et al.   Theranostics

RNA in extracellular vesicles

(2017) Kyoung Mi Kim et al.   Wiley Interdisciplinary Reviews-RNA

Identification of Novel Long Non-coding and Circular RNAs in Human Papillomavirus-Mediated Cervical Cancer

(2017) Hongbo Wang et al.   Frontiers in Microbiology

Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis

(2017) Yibing Yang et al.   JNCI-Journal of the National Cancer Institute

Circular RNAs: Identification, biogenesis and function

(2016) Karoline K. Ebbesen et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Screening and validation of lncRNAs and circRNAs as miRNA sponges

(2016) Giuseppe Militello et al.   BRIEFINGS IN BIOINFORMATICS

Hsa_circ_0001649: A circular RNA and potential novel biomarker for hepatocellular carcinoma

(2016) Meilin Qin et al.   Cancer Biomarkers

Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal Translocations

(2016) Jlenia Guarnerio et al.   CELL

Effect of p53 codon 72 polymorphism on the survival outcome in advanced stage cervical cancer patients in India

(2016) Rita Mulherkar et al.   INDIAN JOURNAL OF MEDICAL RESEARCH

Biomarkers p16, Human Papillomavirus and p53 Predict Recurrence and Survival in Early Stage Squamous Cell Carcinoma of the Vulva

(2016) Casey M. Hay et al.   Journal of Lower Genital Tract Disease

From mobility to crosstalk. A model of intracellular miRNAs motion may explain the RNAs interaction mechanism on the basis of target subcellular localization

(2016) Catalin Vasilescu et al.   MATHEMATICAL BIOSCIENCES

Comprehensive Circular RNA Profiling Reveals That hsa_circ_0005075, a New Circular RNA Biomarker, Is Involved in Hepatocellular Crcinoma Development

(2016) Xingchen Shang et al.   MEDICINE

Detecting circular RNAs: bioinformatic and experimental challenges

(2016) Linda Szabo et al.   NATURE REVIEWS GENETICS

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

(2016) William W. Du et al.   NUCLEIC ACIDS RESEARCH

Identification of senescence-associated circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1

(2016) Amaresh C. Panda et al.   NUCLEIC ACIDS RESEARCH

Inducible RasGEF1B circular RNA is a positive regulator of ICAM-1 in the TLR4/LPS pathway

(2016) Wei Lun Ng et al.   RNA Biology

HPV 16 E7 inhibits OSCC cell proliferation, invasion, and metastasis by upregulating the expression of miR-20a

(2016) Jun Hu et al.   TUMOR BIOLOGY

Comprehensive profile of differentially expressed circular RNAs reveals that hsa_circ_0000069 is upregulated and promotes cell proliferation, migration, and invasion in colorectal cancer

(2016) Jia-ni Guo et al.   OncoTargets and Therapy

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

Emerging roles of circRNA_001569 targeting miR-145 in the proliferation and invasion of colorectal cancer

(2016) Huijun Xie et al.   Oncotarget

Circular RNAs Co-Precipitate with Extracellular Vesicles: A Possible Mechanism for circRNA Clearance

(2016) Erika Lasda et al.   PLoS One

The RNA Binding Protein Quaking Regulates Formation of circRNAs

(2015) Simon J. Conn et al.   CELL

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

(2015) Yan Li et al.   CELL RESEARCH

Comprehensive genomic characterization of head and neck squamous cell carcinomas

(2015)   NATURE

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CircInteractome: A web tool for exploring circular RNAs and their interacting proteins and microRNAs

(2015) Dawood B. Dudekula et al.   RNA Biology

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Analysis of Intron Sequences Reveals Hallmarks of Circular RNA Biogenesis in Animals

(2015) Andranik Ivanov et al.   Cell Reports

Identification and Characterization of Circular RNAs As a New Class of Putative Biomarkers in Human Blood

(2015) Sebastian Memczak et al.   PLoS One

Human Papillomavirus Genotype Prevalence in Invasive Penile Cancers from a Registry-Based United States Population

(2015) Brenda Y. Hernandez et al.   Frontiers in Oncology

Biogenesis of Circular RNAs

(2014) Quentin Vicens et al.   CELL

Complementary Sequence-Mediated Exon Circularization

(2014) Xiao-Ou Zhang et al.   CELL

The Landscape of MicroRNA, Piwi-Interacting RNA, and Circular RNA in Human Saliva

(2014) J. H. Bahn et al.   CLINICAL CHEMISTRY

Human Papillomavirus (HPV)-associated Oral Cancers and Treatment Strategies

(2014) N. Sathish et al.   JOURNAL OF DENTAL RESEARCH

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

Assessing the ceRNA Hypothesis with Quantitative Measurements of miRNA and Target Abundance

(2014) Rémy Denzler et al.   MOLECULAR CELL

The multilayered complexity of ceRNA crosstalk and competition

(2014) Yvonne Tay et al.   NATURE

Detecting and characterizing circular RNAs

(2014) William R Jeck et al.   NATURE BIOTECHNOLOGY

Erratum: Identification and consequences of miRNA–target interactions — beyond repression of gene expression

(2014) Jean Hausser et al.   NATURE REVIEWS GENETICS

microRNAs are biomarkers of oncogenic human papillomavirus infections

(2014) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circular RNAs: diversity of form and function

(2014) Erika Lasda et al.   RNA

Absence of Human Papillomavirus Infection and Activation of PI3K-AKT Pathway in Cervical Clear Cell Carcinoma

(2013) Sayaka Ueno et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Circular Intronic Long Noncoding RNAs

(2013) Yang Zhang et al.   MOLECULAR CELL

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Reducing HPV-Associated Cancer Globally

(2012) D. R. Lowy et al.   Cancer Prevention Research

Human papillomavirus as a favorable prognostic biomarker in squamous cell carcinomas of the vagina

(2012) Immaculada Alonso et al.   GYNECOLOGIC ONCOLOGY

Prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer-systematic review and meta-analysis of trends by time and region

(2012) Hisham Mehanna et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Tobacco Smoking and Increased Risk of Death and Progression for Patients With p16-Positive and p16-Negative Oropharyngeal Cancer

(2012) Maura L. Gillison et al.   JOURNAL OF CLINICAL ONCOLOGY

Codon 72 polymorphism of p53 and HPV type 16 E6 variants as risk factors for patients with squamous epithelial lesion of the uterine cervix

(2012) E. Burroni et al.   JOURNAL OF MEDICAL VIROLOGY

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA

(2011) Thomas B Hansen et al.   EMBO JOURNAL

Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway

(2011) Xin Tong et al.   EMBO REPORTS

Human papillomavirus genotype attribution in invasive cervical cancer: a retrospective cross-sectional worldwide study

(2010) Silvia de Sanjose et al.   LANCET ONCOLOGY

Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer

(2010) K. Kian Ang et al.   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNA Expression Variability in Human Cervical Tissues

(2010) Patrícia M. Pereira et al.   PLoS One

Prognostic factors in the surgical treatment of patients with oral carcinoma

(2009) Rajan S. Patel et al.   ANZ JOURNAL OF SURGERY

Incidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockholm, Sweden: An epidemic of viral-induced carcinoma?

(2009) Anders Näsman et al.   INTERNATIONAL JOURNAL OF CANCER

Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence

(2008) Kotb Abdelmohsen et al.   BIOLOGICAL CHEMISTRY

RNA-binding proteins and post-transcriptional gene regulation

(2008) Tina Glisovic et al.   FEBS LETTERS

Marked differences in survival rate between smokers and nonsmokers with HPV 16-associated tonsillar carcinomas

(2008) Harriët C. Hafkamp et al.   INTERNATIONAL JOURNAL OF CANCER

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

(2008) C. Sahlgren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA