Injectable hydrogel with MSNs/microRNA-21-5p delivery enables both immunomodification and enhanced angiogenesis for myocardial infarction therapy in pigs

Delivery of RNAi-Based Therapeutics for Bone Regeneration

(2020) Dominic W. Malcolm et al.   Current Osteoporosis Reports

MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs

(2019) Khatia Gabisonia et al.   NATURE

Feasibility Study of Mesoporous Silica Particles for Pulmonary Drug Delivery: Therapeutic Treatment with Dexamethasone in a Mouse Model of Airway Inflammation

(2019) Tina Gulin-Sarfraz et al.   Pharmaceutics

The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype

(2019) Priya Hari et al.   Science Advances

RNA interfering molecule delivery from in situ forming biodegradable hydrogels for enhancement of bone formation in rat calvarial bone defects

(2018) Minh K. Nguyen et al.   Acta Biomaterialia

Development of controlled drug delivery systems for bone fracture-targeted therapeutic delivery: A review

(2018) Yuchen Wang et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells

(2018) Bohao Liu et al.   Nature Biomedical Engineering

The toxicity of silica nanoparticles to the immune system

(2018) Liangjiao Chen et al.   Nanomedicine

Lipopolysaccharide-induced inflammation in monocytes/macrophages is blocked by liposomal delivery of Gi-protein inhibitor

(2017) Monica Madalina Tucureanu et al.   International Journal of Nanomedicine

Redirecting cardiac growth mechanisms for therapeutic regeneration

(2017) Ravi Karra et al.   JOURNAL OF CLINICAL INVESTIGATION

Inorganic nanoparticles as potential regulators of immune response in dendritic cells

(2017) Silvia Fogli et al.   Nanomedicine

Cancer Therapy: Injectable Supramolecular Hydrogels as Delivery Agents of Bcl-2 Conversion Gene for the Effective Shrinkage of Therapeutic Resistance Tumors (Adv. Healthcare Mater. 11/2017)

(2017) Xuan Liu et al.   Advanced Healthcare Materials

Sustained miRNA delivery from an injectable hydrogel promotes cardiomyocyte proliferation and functional regeneration after ischaemic injury

(2017) Leo L. Wang et al.   Nature Biomedical Engineering

Micro and Nano Material Carriers for Immunomodulation

(2016) E. Bracho-Sanchez et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Building and re-building the heart by cardiomyocyte proliferation

(2016) Matthew J. Foglia et al.   DEVELOPMENT

Mechanisms of Cardiac Regeneration

(2016) Aysu Uygur et al.   DEVELOPMENTAL CELL

Ultrasensitive pH Triggered Charge/Size Dual-Rebound Gene Delivery System

(2016) Xiuwen Guan et al.   NANO LETTERS

Light-triggered RNA release and induction of hMSC osteogenesis via photodegradable, dual-crosslinked hydrogels

(2016) Cong Truc Huynh et al.   Nanomedicine

Cell-free 3D scaffold with two-stage delivery of miRNA-26a to regenerate critical-sized bone defects

(2016) Xiaojin Zhang et al.   Nature Communications

Mortality in heart failure patients

(2015) Ibadete Bytyçi et al.   Anadolu Kardiyoloji Dergisi-The Anatolian Journal of Cardiology

Technologies for controlled, local delivery of siRNA

(2015) Samantha M. Sarett et al.   JOURNAL OF CONTROLLED RELEASE

MiR-26a Rescues Bone Regeneration Deficiency of Mesenchymal Stem Cells Derived From Osteoporotic Mice

(2015) Yan Li et al.   MOLECULAR THERAPY

Photocleavable Hydrogels for Light-Triggered siRNA Release

(2015) Cong Truc Huynh et al.   Advanced Healthcare Materials

Role of Toll-like receptors in diabetic renal lesions in a miniature pig model

(2015) Y. Feng et al.   Science Advances

Immunotoxicity of silicon dioxide nanoparticles with different sizes and electrostatic charge

(2014) Soo-Ki Kim et al.   International Journal of Nanomedicine

Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition

(2014) Brendan P. Purcell et al.   NATURE MATERIALS

The pig as an animal model for human pathologies: A proteomics perspective

(2014) Anna Bassols et al.   Proteomics Clinical Applications

The promotion of bone regeneration through positive regulation of angiogenic–osteogenic coupling using microRNA-26a

(2013) Yan Li et al.   BIOMATERIALS

Macrophage Plasticity and the Role of Inflammation in Skeletal Muscle Repair

(2013) Yacine Kharraz et al.   MEDIATORS OF INFLAMMATION

Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles

(2013) N. Kamaly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene Therapy That Works

(2013) I. M. Verma   SCIENCE

siRNA Delivery from an Injectable Scaffold for Wound Therapy

(2013) Christopher E. Nelson et al.   Advances in Wound Care

Angiogenesis in the Infarcted Myocardium

(2012) Clement Cochain et al.   ANTIOXIDANTS & REDOX SIGNALING

Functional screening identifies miRNAs inducing cardiac regeneration

(2012) Ana Eulalio et al.   NATURE

Instructive Nanofiber Scaffolds with VEGF Create a Microenvironment for Arteriogenesis and Cardiac Repair

(2012) Y.-D. Lin et al.   Science Translational Medicine

The comparative effects of mesoporous silica nanoparticles and colloidal silica on inflammation and apoptosis

(2011) Soyoung Lee et al.   BIOMATERIALS

Localized, Targeted, and Sustained siRNA Delivery

(2011) Melissa D. Krebs et al.   CHEMISTRY-A EUROPEAN JOURNAL

MicroRNA therapeutics

(2011) J A Broderick et al.   GENE THERAPY

Modulation of cardiac macrophages by phosphatidylserine-presenting liposomes improves infarct repair

(2011) Tamar Harel-Adar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery of basic fibroblast growth factor with a pH-responsive, injectable hydrogel to improve angiogenesis in infarcted myocardium

(2010) Jessica C. Garbern et al.   BIOMATERIALS

Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde

(2010) Heng Ma et al.   EUROPEAN HEART JOURNAL

Breaking down the barriers: siRNA delivery and endosome escape

(2010) M. Dominska et al.   JOURNAL OF CELL SCIENCE