Virus Infections and Host Metabolism—Can We Manage the Interactions?

Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS

(2020) Yushun Wan et al.   JOURNAL OF VIROLOGY

Clinical Characteristics of Coronavirus Disease 2019 in China

(2020) Wei-jie Guan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production

(2020) Valentin Sencio et al.   Cell Reports

Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study

(2020) Xiaobo Yang et al.   Lancet Respiratory Medicine

Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

(2020) Vanessa Monteil et al.   CELL

Obesity and COVID-19 Severity in a Designated Hospital in Shenzhen, China

(2020) Qingxian Cai et al.   DIABETES CARE

Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area

(2020) Safiya Richardson et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation

(2020) Huipeng Jiao et al.   NATURE

Association between Angiotensin Blockade and Incidence of Influenza in the United Kingdom

(2020) Sheng-Chia Chung et al.   NEW ENGLAND JOURNAL OF MEDICINE

High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation

(2020) Arthur Simonnet et al.   Obesity

Is Adipose Tissue a Reservoir for Viral Spread, Immune Activation, and Cytokine Amplification in Coronavirus Disease 2019?

(2020) Paul MacDaragh Ryan et al.   Obesity

Diabetes and COVID-19: A systematic review on the current evidences

(2020) Alireza Abdi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Metabolic Syndrome and Viral Pathogenesis: Lessons from Influenza and Coronaviruses

(2020) Maria Smith et al.   JOURNAL OF VIROLOGY

Impact of obesity on hospitalizations and mortality, due to COVID-19: A systematic review

(2020) João Vitor Vieira de Siqueira et al.   Obesity Research & Clinical Practice

COVID-19 and diabetes mellitus: how one pandemic worsens the other

(2020) William S. Azar et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

COVID-19 in people with diabetes: understanding the reasons for worse outcomes

(2020) Matteo Apicella et al.   Lancet Diabetes & Endocrinology

Individuals with obesity and COVID‐19: A global perspective on the epidemiology and biological relationships

(2020) Barry M. Popkin et al.   Obesity Reviews

HIV-1 Infection and Glucose Metabolism Reprogramming of T Cells: Another Approach Toward Functional Cure and Reservoir Eradication

(2020) Shuang Kang et al.   Frontiers in Immunology

Covid-19 and Diabetes: A Complex Bidirectional Relationship

(2020) Hermine Muniangi-Muhitu et al.   Frontiers in Endocrinology

Supplementing the diet with sodium propionate suppresses the severity of viral immuno-inflammatory lesions

(2020) Deepak Sumbria et al.   JOURNAL OF VIROLOGY

The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons

(2019) Brian P. Daniels et al.   IMMUNITY

How Viral and Intracellular Bacterial Pathogens Reprogram the Metabolism of Host Cells to Allow Their Intracellular Replication

(2019) Wolfgang Eisenreich et al.   Frontiers in Cellular and Infection Microbiology

High ambient temperature dampens adaptive immune responses to influenza A virus infection

(2019) Miyu Moriyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells

(2019) Annabell Bachem et al.   IMMUNITY

Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response

(2019) Krist Helen Antunes et al.   Nature Communications

Impact of Obesity on Influenza A Virus Pathogenesis, Immune Response, and Evolution

(2019) Rebekah Honce et al.   Frontiers in Immunology

Multitasking Kinase RIPK1 Regulates Cell Death and Inflammation

(2019) Kim Newton   Cold Spring Harbor Perspectives in Biology

Cell Death And Zika Virus: An Integrated Network Of The Mechanisms Of Cell Injury

(2019) Jorge Rodrigues de Sousa et al.   Infection and Drug Resistance

Factors Affecting the Tissue Damaging Consequences of Viral Infections

(2019) Deepak Sumbria et al.   Frontiers in Microbiology

Dietary Fiber Confers Protection against Flu by Shaping Ly6c − Patrolling Monocyte Hematopoiesis and CD8 + T Cell Metabolism

(2018) Aurélien Trompette et al.   IMMUNITY

OUP accepted manuscript

(2018)   JOURNAL OF INFECTIOUS DISEASES

On the role of retinoic acid in virus induced inflammatory response in cornea

(2018) Ujjaldeep Jaggi et al.   MICROBES AND INFECTION

Direct effects of thyroid hormones on hepatic lipid metabolism

(2018) Rohit A. Sinha et al.   Nature Reviews Endocrinology

N-3 polyunsaturated fatty acids restore Th17 and Treg balance in collagen antibody-induced arthritis

(2018) Ji Young Kim et al.   PLoS One

Rhinovirus induces an anabolic reprogramming in host cell metabolism essential for viral replication

(2018) Guido A. Gualdoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Omega-6 fatty acids and inflammation

(2018) Jacqueline K. Innes et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Association of NF-E2 Related Factor 2 (Nrf2) and inflammatory cytokines in recent onset Type 2 Diabetes Mellitus

(2018) Dornadula Sireesh et al.   Scientific Reports

How host metabolism impacts on virus pathogenesis

(2018) Siva Karthik Varanasi et al.   Current Opinion in Virology

Epstein–Barr Virus-Induced Metabolic Rearrangements in Human B-Cell Lymphomas

(2018) Pier P. Piccaluga et al.   Frontiers in Microbiology

Anaplerotic Role of Glucose in the Oxidation of Endogenous Fatty Acids during Dengue Virus Infection

(2018) Lorena O. Fernandes-Siqueira et al.   mSphere

Cellular Metabolism Is a Major Determinant of HIV-1 Reservoir Seeding in CD4+ T Cells and Offers an Opportunity to Tackle Infection

(2018) José Carlos Valle-Casuso et al.   Cell Metabolism

Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: a retrospective study

(2018) F.Y. Alqahtani et al.   EPIDEMIOLOGY AND INFECTION

Obesity-Induced Changes in T-Cell Metabolism Are Associated With Impaired Memory T-Cell Response to Influenza and Are Not Reversed With Weight Loss

(2018) Jennifer Rebeles et al.   JOURNAL OF INFECTIOUS DISEASES

Fatty Acid Synthase Promotes the Palmitoylation of Chikungunya Virus nsP1

(2018) Na Zhang et al.   JOURNAL OF VIROLOGY

25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model

(2017) Chunfeng Li et al.   IMMUNITY

Receipt of thyroid hormone deficiency treatment and risk of herpes zoster

(2017) Shao-Chung V. Hsia et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Characterization of ACE and ACE2 Expression within Different Organs of the NOD Mouse

(2017) Heleia Roca-Ho et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glutamine supplementation suppresses herpes simplex virus reactivation

(2017) Kening Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Manipulating Glucose Metabolism during Different Stages of Viral Pathogenesis Can Have either Detrimental or Beneficial Effects

(2017) Siva Karthik Varanasi et al.   JOURNAL OF IMMUNOLOGY

Glycolysis, Glutaminolysis, and Fatty Acid Synthesis Are Required for Distinct Stages of Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication

(2017) Erica L. Sanchez et al.   JOURNAL OF VIROLOGY

Mice with type 1 diabetes exhibit increased susceptibility to influenza A virus

(2017) Caiyun Huo et al.   MICROBIAL PATHOGENESIS

Cellular fatty acid synthase is required for late stages of HIV-1 replication

(2017) Manjusha M. Kulkarni et al.   Retrovirology

5-Hydroxytryptophan, a major product of tryptophan degradation, is essential for optimal replication of human parainfluenza virus

(2017) M.A.G Rabbani et al.   VIROLOGY

The Effect of Short-Term Hyperglycemia on the Innate Immune System

(2016) Nagham Jafar et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation

(2016) Andrew Wang et al.   CELL

Glutamate metabolism in HIV-1 infected macrophages: Role of HIV-1 Vpr

(2016) Prasun K. Datta et al.   CELL CYCLE

Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function

(2016) Duojiao Wu et al.   IMMUNITY

Protective Effects of Glutamine Antagonist 6-Diazo-5-Oxo-l-Norleucine in Mice with Alphavirus Encephalomyelitis

(2016) Sivabalan Manivannan et al.   JOURNAL OF VIROLOGY

Effects of Interferons and Viruses on Metabolism

(2016) Stephanie Deborah Fritsch et al.   Frontiers in Immunology

Modification of the Host Cell Lipid Metabolism Induced by Hypolipidemic Drugs Targeting the Acetyl Coenzyme A Carboxylase Impairs West Nile Virus Replication

(2015) Teresa Merino-Ramos et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Current Concepts for Genital Herpes Simplex Virus Infection: Diagnostics and Pathogenesis of Genital Tract Shedding

(2015) C. Johnston et al.   CLINICAL MICROBIOLOGY REVIEWS

Influence of thyroid hormone disruption on the incidence of shingles

(2015) A. AJAVON et al.   EPIDEMIOLOGY AND INFECTION

Obesity Increases Mortality and Modulates the Lung Metabolome during Pandemic H1N1 Influenza Virus Infection in Mice

(2015) J. Justin Milner et al.   JOURNAL OF IMMUNOLOGY

Latent KSHV Infected Endothelial Cells Are Glutamine Addicted and Require Glutaminolysis for Survival

(2015) Erica L. Sanchez et al.   PLoS Pathogens

Modification of β-Defensin-2 by Dicarbonyls Methylglyoxal and Glyoxal Inhibits Antibacterial and Chemotactic Function In Vitro

(2015) Janna G. Kiselar et al.   PLoS One

Urinary Angiotensin-Converting Enzyme 2 in Hypertensive Patients May Be Increased by Olmesartan, an Angiotensin II Receptor Blocker

(2014) M. Furuhashi et al.   AMERICAN JOURNAL OF HYPERTENSION

Adenovirus E4ORF1-Induced MYC Activation Promotes Host Cell Anabolic Glucose Metabolism and Virus Replication

(2014) Minh Thai et al.   Cell Metabolism

Monocyte Activation from Interferon-α in HIV Infection Increases Acetylated LDL Uptake and ROS Production

(2014) Lynn Pulliam et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Vaccinia Virus Requires Glutamine but Not Glucose for Efficient Replication

(2014) K. A. Fontaine et al.   JOURNAL OF VIROLOGY

Dengue Virus Induces and Requires Glycolysis for Optimal Replication

(2014) Krystal A. Fontaine et al.   JOURNAL OF VIROLOGY

Targeting Epstein–Barr virus oncoprotein LMP1-mediated glycolysis sensitizes nasopharyngeal carcinoma to radiation therapy

(2014) L Xiao et al.   ONCOGENE

Thyroid Hormone Regulation of Metabolism

(2014) Rashmi Mullur et al.   PHYSIOLOGICAL REVIEWS

Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions

(2014) L. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 pathogenicity and virion production are dependent on the metabolic phenotype of activated CD4+ T cells

(2014) Andrea Hegedus et al.   Retrovirology

Angiotensin-converting enzyme 2 (ACE2) mediates influenza H7N9 virus-induced acute lung injury

(2014) Penghui Yang et al.   Scientific Reports

De novo Fatty Acid Biosynthesis Contributes Significantly to Establishment of a Bioenergetically Favorable Environment for Vaccinia Virus Infection

(2014) Matthew D. Greseth et al.   PLoS Pathogens

Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection

(2013) Clovis S. Palmer et al.   AIDS

Treating influenza with statins and other immunomodulatory agents

(2013) David S. Fedson   ANTIVIRAL RESEARCH

West Nile virus and kidney disease

(2013) Luisa Barzon et al.   Expert Review of Anti-Infective Therapy

High glucose modulates IL-6 mediated immune homeostasis through impeding neutrophil extracellular trap formation

(2013) Manjunath B. Joshi et al.   FEBS LETTERS

Parental Dietary Fat Intake Alters Offspring Microbiome and Immunity

(2013) I. A. Myles et al.   JOURNAL OF IMMUNOLOGY

Obesity Impairs Lymphatic Fluid Transport and Dendritic Cell Migration to Lymph Nodes

(2013) Evan S. Weitman et al.   PLoS One

Glycolytic control of vacuolar-type ATPase activity: A mechanism to regulate influenza viral infection

(2013) Hinissan P. Kohio et al.   VIROLOGY

Mature neurons: equipped for survival

(2013) A J Kole et al.   Cell Death & Disease

Steroid-like signalling by interferons: making sense of specific gene activation by cytokines

(2012) Howard M. Johnson et al.   BIOCHEMICAL JOURNAL

Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol

(2012) Su-Yang Liu et al.   IMMUNITY

Influenza pandêmica A (H1N1) 2009: fatores de risco para o internamento

(2012) Luana Lenzi et al.   Jornal Brasileiro de Pneumologia

Deregulation of lipid metabolism pathway genes in nasopharyngeal carcinoma cells

(2012) MAELINDA DAKER et al.   Molecular Medicine Reports

Diabetic Mice Show an Aggravated Course of Herpes-Simplex Virus–Induced Facial Nerve Paralysis

(2012) Shinichi Esaki et al.   OTOLOGY & NEUROTOLOGY

Glut1-mediated glucose transport regulates HIV infection

(2012) S. Loisel-Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma

(2012) A. P. Bhatt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutamine and Leucine Provide Enhanced Protective Immunity Against Mucosal Infection with Herpes Simplex Virus Type 1

(2012) Erdenebileg Uyangaa et al.   Immune Network

Risk Factors for Severe Illness with 2009 Pandemic Influenza A (H1N1) Virus Infection in China

(2011) Hongjie Yu et al.   CLINICAL INFECTIOUS DISEASES

Disruption of Thyroid Hormone Activation in Type 2 Deiodinase Knockout Mice Causes Obesity With Glucose Intolerance and Liver Steatosis Only at Thermoneutrality

(2011) M. Castillo et al.   DIABETES

Obesity is associated with impaired immune response to influenza vaccination in humans

(2011) P A Sheridan et al.   INTERNATIONAL JOURNAL OF OBESITY

Impaired Wound Healing Predisposes Obese Mice to Severe Influenza Virus Infection

(2011) Kevin B. O’Brien et al.   JOURNAL OF INFECTIOUS DISEASES

The imbalance of Th17/Th1/Tregs in patients with type 2 diabetes: relationship with metabolic factors and complications

(2011) Chun Zeng et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Urinary angiotensin-converting enzyme 2 in patients with CKD

(2011) SONOO MIZUIRI et al.   NEPHROLOGY

West Nile Virus Replication Requires Fatty Acid Synthesis but Is Independent on Phosphatidylinositol-4-Phosphate Lipids

(2011) Miguel A. Martín-Acebes et al.   PLoS One

HIV Protease Inhibitors Act as Competitive Inhibitors of the Cytoplasmic Glucose Binding Site of GLUTs with Differing Affinities for GLUT1 and GLUT4

(2011) Richard C. Hresko et al.   PLoS One

Metabolite profiles of human immunodeficiency virus infected CD4+ T cells and macrophages using LC–MS/MS analysis

(2011) Joseph A. Hollenbaugh et al.   VIROLOGY

Divergent Effects of Human Cytomegalovirus and Herpes Simplex Virus-1 on Cellular Metabolism

(2011) Livia Vastag et al.   PLoS Pathogens

Metabolic effects of influenza virus infection in cultured animal cells: Intra- and extracellular metabolite profiling

(2010) Joachim B Ritter et al.   BMC Systems Biology

Dengue Virus-Induced Autophagy Regulates Lipid Metabolism

(2010) Nicholas S. Heaton et al.   Cell Host & Microbe

Thyroid hormone controls the gene expression of HSV-1 LAT and ICP0 in neuronal cells

(2010) Gautam R Bedadala et al.   CELL RESEARCH

Diabetes and the Severity of Pandemic Influenza A (H1N1) Infection

(2010) R. Allard et al.   DIABETES CARE

Elevated Proinflammatory Cytokine Production by a Skewed T Cell Compartment Requires Monocytes and Promotes Inflammation in Type 2 Diabetes

(2010) M. Jagannathan-Bogdan et al.   JOURNAL OF IMMUNOLOGY

Morbid Obesity as a Risk Factor for Hospitalization and Death Due to 2009 Pandemic Influenza A(H1N1) Disease

(2010) Oliver W. Morgan et al.   PLoS One

Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis

(2010) N. S. Heaton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficacy of inactivated vaccine against H5N1 influenza virus infection in mice with type 1 diabetes

(2010) J. Wu et al.   VACCINE

Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics

(2010) Deborah L. Diamond et al.   PLoS Pathogens

Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes

(2009) Jin-Kui Yang et al.   ACTA DIABETOLOGICA

Protease inhibitors used in the treatment of HIV+ induce β-cell apoptosis via the mitochondrial pathway and compromise insulin secretion

(2009) Sheng Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Obesity accelerates thymic aging

(2009) H. Yang et al.   BLOOD

Clinical characteristics and outcomes of diabetic patients with Staphylococcus aureus bacteremia and endocarditis

(2009) Z. A. Kanafani et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Factors Associated With Death or Hospitalization Due to Pandemic 2009 Influenza A(H1N1) Infection in California

(2009) Janice K. Louie   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Comparison of Varicella‐Zoster Virus–Specific Immunity of Patients with Diabetes Mellitus and Healthy Individuals

(2009) Shigefumi Okamoto et al.   JOURNAL OF INFECTIOUS DISEASES

Fish Oil-Fed Mice Have Impaired Resistance to Influenza Infection

(2009) Nicole M. J. Schwerbrock et al.   JOURNAL OF NUTRITION

Glutamine Metabolism Is Essential for Human Cytomegalovirus Infection

(2009) J. W. Chambers et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus-Linked Mitochondrial Dysfunction Promotes Hypoxia-Inducible Factor 1 -Mediated Glycolytic Adaptation

(2009) M. Ripoli et al.   JOURNAL OF VIROLOGY

Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment

(2009) Olaia Naveiras et al.   NATURE

Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia

(2008) M. E. Stegenga et al.   BLOOD

Fatty acid synthase is up-regulated during hepatitis C virus infection and regulates hepatitis C virus entry and production

(2008) Wei Yang et al.   HEPATOLOGY

Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy

(2008) Joshua Munger et al.   NATURE BIOTECHNOLOGY

Effect of host cell lipid metabolism on alphavirus replication, virion morphogenesis, and infectivity

(2008) C. G. Ng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA