Evaluating the Influence of a G-Quadruplex Prone Sequence on the Transactivation Potential by Wild-Type and/or Mutant P53 Family Proteins through a Yeast-Based Functional Assay

Pharmacological prospects of G-quadruplexes for neurological diseases using porphyrins

(2020) Sefan Asamitsu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites

(2020) Elodie Gazanion et al.   PLoS Genetics

An Updated Focus on Quadruplex Structures as Potential Therapeutic Targets in Cancer

(2020) Victoria Sanchez-Martin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

G-Quadruplex Modulation of SP1 Functional Binding Sites at the KIT Proximal Promoter

(2020) Silvia Da Ros et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recent Update on Targeting c-MYC G-Quadruplexes by Small Molecules for Anticancer Therapeutics

(2020) Ritapa Chaudhuri et al.   JOURNAL OF MEDICINAL CHEMISTRY

The MDM2 inducible promoter folds into four-tetrad antiparallel G-quadruplexes targetable to fight malignant liposarcoma

(2020) Sara Lago et al.   NUCLEIC ACIDS RESEARCH

The complex architecture of p53 binding sites

(2020) Alon Senitzki et al.   NUCLEIC ACIDS RESEARCH

G-Quadruplexes in RNA Biology: Recent Advances and Future Directions

(2020) Leïla Dumas et al.   TRENDS IN BIOCHEMICAL SCIENCES

Whole genome experimental maps of DNA G-quadruplexes in multiple species

(2019) Giovanni Marsico et al.   NUCLEIC ACIDS RESEARCH

Stable G-Quadruplex Structures of Oncogene Promoters Induce Potassium-Dependent Stops of Thermostable DNA Polymerase

(2019) G. V. Chashchina et al.   BIOCHEMISTRY-MOSCOW

Modulation of DNA structure formation using small molecules

(2019) Imee M.A. del Mundo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Tissue-specific roles of p73 in development and homeostasis

(2019) Alice Nemajerova et al.   JOURNAL OF CELL SCIENCE

The role of RNA G‐quadruplexes in human diseases and therapeutic strategies

(2019) Prakash Kharel et al.   Wiley Interdisciplinary Reviews-RNA

Yeast As a Chassis for Developing Functional Assays to Study Human P53

(2019) Paola Monti et al.   Jove-Journal of Visualized Experiments

Specific Recognition of Promoter G-Quadruplex DNAs by Small Molecule Ligands and Light-up Probes

(2019) V. Dhamodharan et al.   ACS Chemical Biology

The Rich World of p53 DNA Binding Targets: The Role of DNA Structure

(2019) Václav Brázda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Influence of Quadruplex Structure in Proximity to P53 Target Sequences on the Transactivation Potential of P53 Alpha Isoforms

(2019) Otília Porubiaková et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A mouse model of the Δ133p53 isoform: roles in cancer progression and inflammation

(2018) Marina Kazantseva et al.   MAMMALIAN GENOME

Revealing a human p53 universe

(2018) Thuy-Ai T Nguyen et al.   NUCLEIC ACIDS RESEARCH

Recognition of Local DNA Structures by p53 Protein

(2017) Václav Brázda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Wild-type p53 binds to MYC promoter G-quadruplex

(2016) M. Petr et al.   BIOSCIENCE REPORTS

Re-evaluation of G-quadruplex propensity with G4Hunter

(2016) Amina Bedrat et al.   NUCLEIC ACIDS RESEARCH

Gain of function of mutant p53: R282W on the peak?

(2016) Y Zhang et al.   Oncogenesis

Oncogenic Intra-p53 Family Member Interactions in Human Cancers

(2016) Maria Ferraiuolo et al.   Frontiers in Oncology

IFI16 Preferentially Binds to DNA with Quadruplex Structure and Enhances DNA Quadruplex Formation

(2016) Lucia Hároníková et al.   PLoS One

G-quadruplexes and their regulatory roles in biology

(2015) Daniela Rhodes et al.   NUCLEIC ACIDS RESEARCH

∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.

(2015) Paola Monti et al.   Oncotarget

DNA and RNA Quadruplex-Binding Proteins

(2014) Václav Brázda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Preferential binding of p53 tumor suppressor to p21 promoter sites that contain inverted repeats capable of forming cruciform structure

(2013) Jan Coufal et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The G-Quadruplex Augments Translation in the 5′ Untranslated Region of Transforming Growth Factor β2

(2013) Prachi Agarwala et al.   BIOCHEMISTRY

EEC- and ADULT-AssociatedTP63Mutations Exhibit Functional Heterogeneity Toward P63 Responsive Sequences

(2013) Paola Monti et al.   HUMAN MUTATION

Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code

(2013) Y. Ciribilli et al.   NUCLEIC ACIDS RESEARCH

Mutant p53 is a transcriptional co-factor that binds to G-rich regulatory regions of active genes and generates transcriptional plasticity

(2012) Timo Quante et al.   CELL CYCLE

Dominant-Negative Features of Mutant TP53 in Germline Carriers Have Limited Impact on Cancer Outcomes

(2011) P. Monti et al.   MOLECULAR CANCER RESEARCH

p53 Transactivation and the Impact of Mutations, Cofactors and Small Molecules Using a Simplified Yeast-Based Screening System

(2011) Virginia Andreotti et al.   PLoS One

p53-family proteins and their regulators: hubs and spokes in tumor suppression

(2010) L Collavin et al.   CELL DEATH AND DIFFERENTIATION

Structure, location and interactions of G-quadruplexes

(2010) Julian L. Huppert   FEBS Journal

Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs

(2010) Malka Kitayner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Sequence-dependent cooperative binding of p53 to DNA targets and its relationship to the structural properties of the DNA targets

(2010) Itai Beno et al.   NUCLEIC ACIDS RESEARCH

p63 and p73, the Ancestors of p53

(2010) V. Dotsch et al.   Cold Spring Harbor Perspectives in Biology

Novel p63 target genes involved in paracrine signaling and keratinocyte differentiation

(2010) C E Barton et al.   Cell Death & Disease

G-Quadruplex DNA Sequences Are Evolutionarily Conserved and Associated with Distinct Genomic Features in Saccharomyces cerevisiae

(2010) John A. Capra et al.   PLoS Computational Biology

An Unusually Stable G-Quadruplex within the 5′-UTR of the MT3 Matrix Metalloproteinase mRNA Represses Translation in Eukaryotic Cells

(2009) Mark J. Morris et al.   BIOCHEMISTRY

Conservation of DNA-binding specificity and oligomerisation properties within the p53 family

(2009) Tobias Brandt et al.   BMC GENOMICS

ΔNp63α-dependent expression of Id-3 distinctively suppresses the invasiveness of human squamous cell carcinoma

(2009) Koichiro Higashikawa et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of VDR by  Np63  is associated with inhibition of cell invasion

(2009) R. Kommagani et al.   JOURNAL OF CELL SCIENCE

An Active Role of the ΔN Isoform of p63 in Regulating Basal Keratin Genes K5 and K14 and Directing Epidermal Cell Fate

(2009) Rose-Anne Romano et al.   PLoS One

G-quadruplex structures: in vivo evidence and function

(2009) Hans J. Lipps et al.   TRENDS IN CELL BIOLOGY

DNA topology influences p53 sequence-specific DNA binding through structural transitions within the target sites

(2008) Eva B. Jagelská et al.   BIOCHEMICAL JOURNAL

Hunting G-quadruplexes

(2008) J.L. Huppert   BIOCHIMIE

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY