IFI16 Preferentially Binds to DNA with Quadruplex Structure and Enhances DNA Quadruplex Formation

Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription

(2015) Elena Tosoni et al.   NUCLEIC ACIDS RESEARCH

G-quadruplexes and their regulatory roles in biology

(2015) Daniela Rhodes et al.   NUCLEIC ACIDS RESEARCH

U3 Region in the HIV-1 Genome Adopts a G-Quadruplex Structure in Its RNA and DNA Sequence

(2014) Dorota Piekna-Przybylska et al.   BIOCHEMISTRY

Innate DNA sensing is impaired in HIV patients and IFI16 expression correlates with chronic immune activation

(2014) S. K. Nissen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Polymorphism inIFI16affects CD4+T-cell counts in HIV-1 infection

(2014) T. Booiman et al.   International Journal of Immunogenetics

DNA and RNA Quadruplex-Binding Proteins

(2014) Václav Brázda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Assembly and Intermolecular Properties of the Hsp70-Tomm34-Hsp90 Molecular Chaperone Complex

(2014) Filip Trcka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interferon γ-inducible Protein (IFI) 16 Transcriptionally Regulates Type I Interferons and Other Interferon-stimulated Genes and Controls the Interferon Response to both DNA and RNA Viruses

(2014) Mikayla R. Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

G-quadruplexes regulate Epstein-Barr virus–encoded nuclear antigen 1 mRNA translation

(2014) Pierre Murat et al.   Nature Chemical Biology

Human Papillomavirus G-Quadruplexes

(2013) Katarína Tlučková et al.   BIOCHEMISTRY

Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly

(2013) Tengchuan Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Constitutive Interferon-Inducible Protein 16-Inflammasome Activation during Epstein-Barr Virus Latency I, II, and III in B and Epithelial Cells

(2013) M. A. Ansari et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus 1 Infection Induces Activation and Subsequent Inhibition of the IFI16 and NLRP3 Inflammasomes

(2013) K. E. Johnson et al.   JOURNAL OF VIROLOGY

Kaposi's Sarcoma-Associated Herpesvirus Latency in Endothelial and B Cells Activates Gamma Interferon-Inducible Protein 16-Mediated Inflammasomes

(2013) V. V. Singh et al.   JOURNAL OF VIROLOGY

MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice

(2013) Susanna Cogoi et al.   NUCLEIC ACIDS RESEARCH

Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy

(2013) S. R. Morrone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV

(2013) K. M. Monroe et al.   SCIENCE

Preferential binding of IFI16 protein to cruciform structure and superhelical DNA

(2012) Václav Brázda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The mammalian PYHIN gene family: Phylogeny, evolution and expression

(2012) Jasmyn A Cridland et al.   BMC EVOLUTIONARY BIOLOGY

Mutant p53 is a transcriptional co-factor that binds to G-rich regulatory regions of active genes and generates transcriptional plasticity

(2012) Timo Quante et al.   CELL CYCLE

Circular Dichroism Spectroscopy of DNA: From Duplexes to Quadruplexes

(2012) Michaela Vorlíčková et al.   CHIRALITY

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

(2012) Tengchuan Jin et al.   IMMUNITY

Extensive evolutionary and functional diversity among mammalian AIM2-like receptors

(2012) Rebecca L. Brunette et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Polymorphism of human telomeric quadruplex structure controlled by DNA concentration: a Raman study

(2012) Jan Palacký et al.   NUCLEIC ACIDS RESEARCH

The Guanine-Quadruplex Structure in the Human c-myc Gene's Promoter Is Converted into B-DNA Form by the Human Poly(ADP-Ribose)Polymerase-1

(2012) Anna Fekete et al.   PLoS One

Acetylation modulates cellular distribution and DNA sensing ability of interferon-inducible protein IFI16

(2012) T. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cruciform structures are a common DNA feature important for regulating biological processes

(2011) Václav Brázda et al.   BMC MOLECULAR BIOLOGY

IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection

(2011) Nagaraj Kerur et al.   Cell Host & Microbe

Interferon-inducible p200-family protein IFI16, an innate immune sensor for cytosolic and nuclear double-stranded DNA: Regulation of subcellular localization

(2011) Sudhakar Veeranki et al.   MOLECULAR IMMUNOLOGY

G-quadruplex formation at the 3' end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase

(2011) Q. Wang et al.   NUCLEIC ACIDS RESEARCH

Interferon-Inducible Protein 16: Insight into the Interaction with Tumor Suppressor p53

(2011) Jack C.C. Liao et al.   STRUCTURE

Redistribution of the nuclear protein IFI16 into the cytoplasm of ultraviolet B-exposed keratinocytes as a mechanism of autoantigen processing

(2010) S. Costa et al.   BRITISH JOURNAL OF DERMATOLOGY

IFI16 is an innate immune sensor for intracellular DNA

(2010) Leonie Unterholzner et al.   NATURE IMMUNOLOGY

Interferon-Inducible IFI16, a Negative Regulator of Cell Growth, Down-Regulates Expression of Human Telomerase Reverse Transcriptase (hTERT) Gene

(2010) Lynda Li Song et al.   PLoS One

Identification and Characterization of Nucleolin as a c-mycG-quadruplex-binding Protein

(2009) Verónica González et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IFI16 and NM23 bind to a common DNA fragment both in theP53and thecMYCgene promoters

(2009) Lorenza Egistelli et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Arrangements of human telomere DNA quadruplex in physiologically relevant K + solutions

(2009) D. Renčiuk et al.   NUCLEIC ACIDS RESEARCH

RPA nucleic acid-binding properties of IFI16-HIN200

(2008) Hongyue Yan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Role of IFI16 in DNA damage and checkpoint

(2007) Mutsuko Ouchi   Frontiers in Bioscience-Landmark