Gain of function of mutant p53: R282W on the peak?

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome

(2015) Paul M. Neilsen et al.   Oncotarget

Gain-of-function of mutant p53: mutant p53 enhances cancer progression by inhibiting KLF17 expression in invasive breast carcinoma cells

(2014) Amjad Ali et al.   CANCER LETTERS

Unequal prognostic potentials of p53 gain-of-function mutations in human cancers associate with drug-metabolizing activity

(2014) J Xu et al.   Cell Death & Disease

The Effect of microRNAs in the Regulation of Human CYP3A4: a Systematic Study using a Mathematical Model

(2014) Zhiyun Wei et al.   Scientific Reports

Heterogeneity of Li-Fraumeni Syndrome links to unequal gain-of-function effects of p53 mutations

(2014) Jie Xu et al.   Scientific Reports

Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

(2013) Tomer Cooks et al.   CANCER CELL

Not all p53 gain-of-function mutants are created equal

(2013) S S Mello et al.   CELL DEATH AND DIFFERENTIATION

Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis

(2013) W Hanel et al.   CELL DEATH AND DIFFERENTIATION

Prevalence and Co-Occurrence of Actionable Genomic Alterations in High-Grade Bladder Cancer

(2013) Gopa Iyer et al.   JOURNAL OF CLINICAL ONCOLOGY

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

Mutant p53 drives invasion in breast tumors through up-regulation of miR-155

(2012) P M Neilsen et al.   ONCOGENE

Structural Effects of the L145Q, V157F, and R282W Cancer-Associated Mutations in the p53 DNA-Binding Core Domain

(2011) Sara Calhoun et al.   BIOCHEMISTRY

p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53

(2011) G Melino   CELL DEATH AND DIFFERENTIATION

TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence

(2011) H. D. Skinner et al.   CLINICAL CANCER RESEARCH

p53 and its mutants in tumor cell migration and invasion

(2011) Patricia A. J. Muller et al.   JOURNAL OF CELL BIOLOGY

Hidden order revealed

(2011) Michael E. Flatté   Nature Physics

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

KLF17 is a negative regulator of epithelial–mesenchymal transition and metastasis in breast cancer

(2009) Kiranmai Gumireddy et al.   NATURE CELL BIOLOGY

Mutant p53 Gain-of-Function in Cancer

(2009) M. Oren et al.   Cold Spring Harbor Perspectives in Biology

The mitochondrial p53 pathway

(2008) Angelina V. Vaseva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS