Gastrodin Inhibits Virus Infection by Promoting the Production of Type I Interferon

DNA Sensing in the Innate Immune Response

(2020) Benoit Briard et al.   PHYSIOLOGY

HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain infection

(2020) Chiranjeevi Bodda et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The improvement effect of gastrodin on LPS/GalN-induced fulminant hepatitis via inhibiting inflammation and apoptosis and restoring autophagy

(2020) Hongming Lv et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling

(2020) Benjamin Israelow et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness

(2020) Kizzmekia S. Corbett et al.   NATURE

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

(2020) Jérôme Hadjadj et al.   SCIENCE

Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) by Mass Spectrometry

(2020) Petra Wandernoth et al.   Viruses-Basel

SARS-CoV-2 infection in China—Before the pandemic

(2020) Huiying Liang et al.   PLoS Neglected Tropical Diseases

Interplay between SARS-CoV-2 and the type I interferon response

(2020) Margarida Sa Ribero et al.   PLoS Pathogens

Gastrodin ameliorates microvascular reperfusion injury–induced pyroptosis by regulating the NLRP3/caspase-1 pathway

(2019) Wenjing Sun et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Cellular MicroRNA Expression Profile of Chicken Macrophages Infected with Newcastle Disease Virus Vaccine Strain LaSota

(2019) Jiaqi Mu et al.   Pathogens

MicroRNA-33/33* inhibit the activation of MAVS through AMPK in antiviral innate immunity

(2019) Danhui Liu et al.   Cellular & Molecular Immunology

Zika Virus Non-Structural Protein NS5 Inhibits the RIG-I Pathway and Interferon Lambda 1 Promoter Activation by Targeting IKK Epsilon

(2019) Lundberg et al.   Viruses-Basel

IFN-Lambda 3 Mediates Antiviral Protection Against Porcine Epidemic Diarrhea Virus by Inducing a Distinct Antiviral Transcript Profile in Porcine Intestinal Epithelia

(2019) Liang Li et al.   Frontiers in Immunology

Dampened STING-Dependent Interferon Activation in Bats

(2018) Jiazheng Xie et al.   Cell Host & Microbe

Tumor-derived exosomes antagonize innate antiviral immunity

(2018) Liang Gao et al.   NATURE IMMUNOLOGY

A Review on Central Nervous System Effects of Gastrodin

(2018) Yuan Liu et al.   Frontiers in Pharmacology

Gastrodin Protects Cardiomyocytes from Anoxia/Reoxygenation Injury by 14-3-3η

(2018) Meifang Zhu et al.   Oxidative Medicine and Cellular Longevity

Type I IFN signaling blockade by a PASylated antagonist during chronic SIV infection suppresses specific inflammatory pathways but does not alter T cell activation or virus replication

(2018) Krystelle Nganou-Makamdop et al.   PLoS Pathogens

The influence of interferon on healthy and diseased skin

(2018) Grace A. Hile et al.   CYTOKINE

A Conserved Residue, Tyrosine (Y) 84, in H5N1 Influenza A Virus NS1 Regulates IFN Signaling Responses to Enhance Viral Infection

(2017) Ben Wang et al.   Viruses-Basel

E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses

(2017) Yinjing Song et al.   Nature Communications

Proliferation-enhancing effects of gastrodin on RSC96 Schwann cells by regulating ERK1/2 and PI3K signaling pathways

(2016) Wenpu Zuo et al.   BIOMEDICINE & PHARMACOTHERAPY

IFN-α, IFN-β, and IFN-γ Have Different Effect on the Production of Proinflammatory Factors Deposited in Weibel-Palade Bodies of Endothelial Cells Infected with Herpes Simplex Virus Type 1

(2016) O. N. Shcheglovitova et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

(2016) Rudragouda Channappanavar et al.   Cell Host & Microbe

HSV‐1 ICP27 targets the TBK1‐activated STING signalsome to inhibit virus‐induced type I IFN expression

(2016) Maria H Christensen et al.   EMBO JOURNAL

MicroRNA-223 Promotes Type I Interferon Production in Antiviral Innate Immunity by Targeting Forkhead Box Protein O3 (FOXO3)

(2016) Luoquan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fast type I interferon response protects astrocytes from flavivirus infection and virus-induced cytopathic effects

(2016) Richard Lindqvist et al.   Journal of Neuroinflammation

Pathogen-Associated Molecular Patterns Induced Crosstalk between Dendritic Cells, T Helper Cells, and Natural Killer Helper Cells Can Improve Dendritic Cell Vaccination

(2016) Tammy Oth et al.   MEDIATORS OF INFLAMMATION

Protective effect of gastrodin on bile duct ligation-induced hepatic fibrosis in rats

(2015) Shuangshuang Zhao et al.   FOOD AND CHEMICAL TOXICOLOGY

HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation

(2014) Maria Kalamvoki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Siglec-G by RNA Viruses Inhibits the Innate Immune Response by Promoting RIG-I Degradation

(2013) Weilin Chen et al.   CELL

Herpes Simplex Virus 1-Encoded Tegument Protein VP16 Abrogates the Production of Beta Interferon (IFN) by Inhibiting NF- B Activation and Blocking IFN Regulatory Factor 3 To Recruit Its Coactivator CBP

(2013) J. Xing et al.   JOURNAL OF VIROLOGY

Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses

(2013) D. Gao et al.   SCIENCE

Gastrodin protects against cardiac hypertrophy and fibrosis

(2011) Chunming Shu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Comprehensive Characterization of Interaction Complexes of Herpes Simplex Virus Type 1 ICP22, UL3, UL4, and UL20.5

(2010) J. Xing et al.   JOURNAL OF VIROLOGY

IFI16 is an innate immune sensor for intracellular DNA

(2010) Leonie Unterholzner et al.   NATURE IMMUNOLOGY

Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll

(2008) Laure El Chamy et al.   NATURE IMMUNOLOGY