Zika Virus Non-Structural Protein NS5 Inhibits the RIG-I Pathway and Interferon Lambda 1 Promoter Activation by Targeting IKK Epsilon

Comparative analysis of African and Asian lineage-derived Zika Virus strains reveals differences in activation of and sensitivity to antiviral innate immunity.

(2019) Katharina Esser-Nobis et al.   JOURNAL OF VIROLOGY

Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling

(2018) Jonny Hertzog et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

(2018) Hongjie Xia et al.   Nature Communications

Zika virus NS5 protein antagonizes type I interferon production via blocking TBK1 activation

(2018) Shaoli Lin et al.   VIROLOGY

Production, purification and immunogenicity of recombinant Ebola virus proteins − A comparison of Freund’s adjuvant and adjuvant system 03

(2017) Krister Melén et al.   JOURNAL OF VIROLOGICAL METHODS

Zika Virus Infects Human Sertoli Cells and Modulates the Integrity of the In Vitro Blood-Testis Barrier Model

(2017) David N. Siemann et al.   JOURNAL OF VIROLOGY

Selective Activation of Type II Interferon Signaling by Zika Virus NS5 Protein

(2017) Vidyanath Chaudhary et al.   JOURNAL OF VIROLOGY

Taking the defensive: Immune control of Zika virus infection

(2017) James R. Bowen et al.   VIRUS RESEARCH

The structure of Zika virus NS5 reveals a conserved domain conformation

(2017) Boxiao Wang et al.   Nature Communications

Structure and function of the Zika virus full-length NS5 protein

(2017) Baoyu Zhao et al.   Nature Communications

Zika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic Cells

(2017) James R. Bowen et al.   PLoS Pathogens

Interferon Lambda Genetics and Biology in Regulation of Viral Control

(2017) Emily A. Hemann et al.   Frontiers in Immunology

Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro

(2017) Yaoxing Wu et al.   Cell Discovery

Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling

(2016) Alesha Grant et al.   Cell Host & Microbe

Zika Virus Infects Human Placental Macrophages

(2016) Kendra M. Quicke et al.   Cell Host & Microbe

Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection

(2016) Avraham Bayer et al.   Cell Host & Microbe

Zika Virus Targets Different Primary Human Placental Cells, Suggesting Two Routes for Vertical Transmission

(2016) Takako Tabata et al.   Cell Host & Microbe

Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth

(2016) Hengli Tang et al.   Cell Stem Cell

Zika Virus

(2016) Didier Musso et al.   CLINICAL MICROBIOLOGY REVIEWS

Zika virus inhibits type‐I interferon production and downstream signaling

(2016) Anil Kumar et al.   EMBO REPORTS

Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives

(2016) Bruno Coutard et al.   JOURNAL OF VIROLOGY

Zika virus: history of a newly emerging arbovirus

(2016) Nitwara Wikan et al.   LANCET INFECTIOUS DISEASES

Zika Virus Infection with Prolonged Maternal Viremia and Fetal Brain Abnormalities

(2016) Rita W. Driggers et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia

(2016) Marco Onorati et al.   Cell Reports

Flavivirus Antagonism of Type I Interferon Signaling Reveals Prolidase as a Regulator of IFNAR1 Surface Expression

(2015) Kirk J. Lubick et al.   Cell Host & Microbe

Characterization of Dengue Virus NS4A and NS4B Protein Interaction

(2015) Jing Zou et al.   JOURNAL OF VIROLOGY

Biology of Zika Virus Infection in Human Skin Cells

(2015) Rodolphe Hamel et al.   JOURNAL OF VIROLOGY

Flaviviral NS4b, chameleon and jack-in-the-box roles in viral replication and pathogenesis, and a molecular target for antiviral intervention

(2015) Joanna Zmurko et al.   REVIEWS IN MEDICAL VIROLOGY

Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets

(2015) Yang Yang et al.   Scientific Reports

The Interferon Signaling Antagonist Function of Yellow Fever Virus NS5 Protein Is Activated by Type I Interferon

(2014) Maudry Laurent-Rolle et al.   Cell Host & Microbe

MAP kinase p38α regulates type III interferon (IFN- λ1 ) gene expression in human monocyte-derived dendritic cells in response to RNA stimulation

(2014) Miao Jiang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

IFITs: Emerging Roles as Key Anti-Viral Proteins

(2014) Gregory I. Vladimer et al.   Frontiers in Immunology

Dengue Virus Subverts the Interferon Induction Pathway via NS2B/3 Protease-IκB Kinase ε Interaction

(2013) Yesseinia I. Angleró-Rodríguez et al.   Clinical and Vaccine Immunology

The multiple faces of proteinkinase R in antiviral defense

(2013) Muhammad Munir et al.   Virulence

Dengue Virus Co-opts UBR4 to Degrade STAT2 and Antagonize Type I Interferon Signaling

(2013) Juliet Morrison et al.   PLoS Pathogens

Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKε and TBK1 functions

(2012) Pasi Kaukinen et al.   JOURNAL OF MEDICAL VIROLOGY

Arenavirus Nucleoprotein Targets Interferon Regulatory Factor-Activating Kinase IKK 

(2012) C. Pythoud et al.   JOURNAL OF VIROLOGY

Innate Immunity Evasion by Dengue Virus

(2012) Juliet Morrison et al.   Viruses-Basel

A supramolecular assembly formed by influenza A virus genomic RNA segments

(2011) Emilie Fournier et al.   NUCLEIC ACIDS RESEARCH

Human MxA Protein: An Interferon-Induced Dynamin-Like GTPase with Broad Antiviral Activity

(2010) Otto Haller et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The Interferon Inducible Gene: Viperin

(2010) Katherine A. Fitzgerald   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The NS5 Protein of the Virulent West Nile Virus NY99 Strain Is a Potent Antagonist of Type I Interferon-Mediated JAK-STAT Signaling

(2010) M. Laurent-Rolle et al.   JOURNAL OF VIROLOGY