Tau Deletion Prevents Cognitive Impairment and Mitochondrial Dysfunction Age Associated by a Mechanism Dependent on Cyclophilin-D

Mitochondria dysfunction in the pathogenesis of Alzheimer’s disease: recent advances

(2020) Wenzhang Wang et al.   Molecular Neurodegeneration

Stimulation of Melanocortin Receptor-4 (MC4R) Prevents Mitochondrial Damage Induced by Binge Ethanol Protocol in Adolescent Rat Hippocampus

(2020) Angie K. Torres et al.   NEUROSCIENCE

Premature synaptic mitochondrial dysfunction in the hippocampus during aging contributes to memory loss

(2020) Margrethe A. Olesen et al.   Redox Biology

It’s all about tau

(2019) Cheril Tapia-Rojas et al.   PROGRESS IN NEUROBIOLOGY

Adolescence binge alcohol consumption induces hippocampal mitochondrial impairment that persists during the adulthood

(2019) Cheril Tapia-Rojas et al.   NEUROSCIENCE

Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics

(2019) Amado Carreras-Sureda et al.   NATURE CELL BIOLOGY

Mitochondrial dysfunction in neurodegenerative diseases and drug targets via apoptotic signaling

(2019) Yuanbo Wu et al.   MITOCHONDRION

Aging and Alzheimer’s disease: Comparison and associations from molecular to system level

(2018) Xian Xia et al.   AGING CELL

Acute tau knockdown in the hippocampus of adult mice causes learning and memory deficits

(2018) Ramon Velazquez et al.   AGING CELL

Mitochondria and aging: A role for the mitochondrial transition pore?

(2018) Mathieu Panel et al.   AGING CELL

Endoplasmic Reticulum Stress Contributes to the Loss of Newborn Hippocampal Neurons after Traumatic Brain Injury

(2018) Kimberly N. Hood et al.   JOURNAL OF NEUROSCIENCE

A role for tau in learning, memory and synaptic plasticity

(2018) Fabrizio Biundo et al.   Scientific Reports

A Larger Social Network Enhances Novel Object Location Memory and Reduces Hippocampal Microgliosis in Aged Mice

(2018) Bryon M. Smith et al.   Frontiers in Aging Neuroscience

Contribution of Tau Pathology to Mitochondrial Impairment in Neurodegeneration

(2018) María J. Pérez et al.   Frontiers in Neuroscience

Genetic ablation of tau improves mitochondrial function and cognitive abilities in the hippocampus

(2018) Claudia Jara et al.   Redox Biology

Caspase-Cleaved Tau Impairs Mitochondrial Dynamics in Alzheimer’s Disease

(2017) María José Pérez et al.   MOLECULAR NEUROBIOLOGY

The effects of aging in the hippocampus and cognitive decline

(2017) Luis E.B. Bettio et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Metabolic Stress Induces Cognitive Disturbances and Inflammation in Aged Mice: Protective Role of Resveratrol

(2017) Veronica Palomera-Ávalos et al.   REJUVENATION RESEARCH

Mitochondrial Dynamics: Coupling Mitochondrial Fitness with Healthy Aging

(2017) David Sebastián et al.   TRENDS IN MOLECULAR MEDICINE

A NH2 Tau Fragment Targets Neuronal Mitochondria at AD Synapses: Possible Implications for Neurodegeneration

(2017) Giuseppina Amadoro et al.   JOURNAL OF ALZHEIMERS DISEASE

Cyclophilin D Promotes Brain Mitochondrial F1FO ATP Synthase Dysfunction in Aging Mice

(2016) Esha Gauba et al.   JOURNAL OF ALZHEIMERS DISEASE

Mitochondrial Ca2+ and regulation of the permeability transition pore

(2016) Stephen Hurst et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Co-immunoprecipitation with Tau Isoform-specific Antibodies Reveals Distinct Protein Interactions and Highlights a Putative Role for 2N Tau in Disease

(2016) Chang Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered Proteins in the Aging Brain

(2016) Adila Elobeid et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Ageing, neurodegeneration and brain rejuvenation

(2016) Tony Wyss-Coray   NATURE

Overexpression of Tau Rescues Nogo-66-Induced Neurite Outgrowth Inhibition In Vitro

(2016) Yu-Chao Zuo et al.   Neuroscience Bulletin

Age-related changes in behavior in C57BL/6J mice from young adulthood to middle age

(2016) Hirotaka Shoji et al.   Molecular Brain

Aging synaptic mitochondria exhibit dynamic proteomic changes while maintaining bioenergetic function

(2016) Kelly L. Stauch et al.   Aging-US

The hippocampus in aging and disease: From plasticity to vulnerability

(2015) T. Bartsch et al.   NEUROSCIENCE

Alcohol hangover induces mitochondrial dysfunction and free radical production in mouse cerebellum

(2015) A.G. Karadayian et al.   NEUROSCIENCE

Cell death disguised: The mitochondrial permeability transition pore as the c-subunit of the F1FO ATP synthase

(2015) Elizabeth A. Jonas et al.   PHARMACOLOGICAL RESEARCH

Lentiviral vectors as tools to understand central nervous system biology in mammalian model organisms

(2015) Louise C. Parr-Brownlie et al.   Frontiers in Molecular Neuroscience

In vivo Activation of Wnt Signaling Pathway Enhances Cognitive Function of Adult Mice and Reverses Cognitive Deficits in an Alzheimer's Disease Model

(2014) J. Y. Vargas et al.   JOURNAL OF NEUROSCIENCE

Phosphorylated tau potentiates Aβ-induced mitochondrial damage in mature neurons

(2014) Rodrigo A. Quintanilla et al.   NEUROBIOLOGY OF DISEASE

What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus

(2014) Anders M. Fjell et al.   PROGRESS IN NEUROBIOLOGY

Mitochondrial Aging and Age-Related Dysfunction of Mitochondria

(2014) Dimitry A. Chistiakov et al.   Biomed Research International

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Age-appropriate cognition and subtle dopamine-independent motor deficits in aged Tau knockout mice

(2013) Meaghan Morris et al.   NEUROBIOLOGY OF AGING

Presynaptic mitochondrial morphology in monkey prefrontal cortex correlates with working memory and is improved with estrogen treatment

(2013) Y. Hara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Propagation of tau pathology in Alzheimer’s disease: identification of novel therapeutic targets

(2013) Amy M Pooler et al.   Alzheimers Research & Therapy

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

(2012) Peng Lei et al.   NATURE MEDICINE

Remote spatial memory in aging: all is not lost

(2012) R. Shayna Rosenbaum et al.   Frontiers in Aging Neuroscience

Production of Lentiviral Vectors for Transducing Cells from the Central Nervous System

(2012) Mingjie Li et al.   Jove-Journal of Visualized Experiments

Synaptic Mitochondrial Pathology in Alzheimer's Disease

(2011) Heng Du et al.   ANTIOXIDANTS & REDOX SIGNALING

Brain aging, Alzheimer's disease, and mitochondria

(2011) Russell H. Swerdlow   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Permeability Transition Pore Controls Cardiac Mitochondrial Maturation and Myocyte Differentiation

(2011) Jennifer R. Hom et al.   DEVELOPMENTAL CELL

Interaction between NH2-tau fragment and Aβ in Alzheimer's disease mitochondria contributes to the synaptic deterioration

(2011) Giuseppina Amadoro et al.   NEUROBIOLOGY OF AGING

Truncated tau and Aβ cooperatively impair mitochondria in primary neurons

(2011) Rodrigo A. Quintanilla et al.   NEUROBIOLOGY OF AGING

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(2010) Yipeng Wang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Tau in Alzheimer Disease and Related Tauopathies

(2010) K. Iqbal et al.   Current Alzheimer Research

Brain mitochondrial dysfunction in aging, neurodegeneration and Parkinson's disease

(2010) Ana Navarro   Frontiers in Aging Neuroscience

Social and Emotional Aging

(2009) Susan T. Charles et al.   Annual Review of Psychology

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(2009) Fimmie Reinecke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

Caspase-cleaved Tau Expression Induces Mitochondrial Dysfunction in Immortalized Cortical Neurons

(2009) Rodrigo A. Quintanilla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium Elevation in Mitochondria Is the Main Ca2+Requirement for Mitochondrial Permeability Transition Pore (mPTP) Opening

(2009) Heidi K. Baumgartner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model

(2009) Heng Du et al.   NEUROBIOLOGY OF AGING

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

(2008) Heng Du et al.   NATURE MEDICINE