Antagonistic control of myofiber size and muscle protein quality control by the ubiquitin ligase UBR4 during aging

Effects of IGF‐1 isoforms on muscle growth and sarcopenia

(2019) Francesca Ascenzi et al.   AGING CELL

Circadian gene variants and the skeletal muscle circadian clock contribute to the evolutionary divergence in longevity across Drosophila populations

(2019) Liam C. Hunt et al.   GENOME RESEARCH

Partial inhibition of mTORC1 in aged rats counteracts the decline in muscle mass and reverses molecular signaling associated with sarcopenia

(2019) Giselle A. Joseph et al.   MOLECULAR AND CELLULAR BIOLOGY

A Key Role for the Ubiquitin Ligase UBR4 in Myofiber Hypertrophy in Drosophila and Mice

(2019) Liam C. Hunt et al.   Cell Reports

MOLECULAR REGULATION OF HUMAN SKELETAL MUSCLE PROTEIN SYNTHESIS IN RESPONSE TO EXERCISE AND NUTRIENTS: A COMPASS FOR OVERCOMING AGE-RELATED ANABOLIC RESISTANCE

(2019) Nathan Hodson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The many functions of ESCRTs

(2019) Marina Vietri et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome

(2018) Sung Tae Kim et al.   JOURNAL OF CELL SCIENCE

The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins

(2018) Sung Tae Kim et al.   PLoS One

Myostatin inhibition using mRK35 produces skeletal muscle growth and tubular aggregate formation in wild type and TgACTA1D286G nemaline myopathy mice

(2017) Jennifer A Tinklenberg et al.   HUMAN MOLECULAR GENETICS

The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes

(2016) Markus M. Rinschen et al.   HUMAN MOLECULAR GENETICS

Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans

(2016) Matthew S. Brook et al.   JOURNAL OF PHYSIOLOGY-LONDON

OASIS 2: online application for survival analysis 2 with features for the analysis of maximal lifespan and healthspan in aging research

(2016) Seong Kyu Han et al.   Oncotarget

Targeting of Fn14 Prevents Cancer-Induced Cachexia and Prolongs Survival

(2015) Amelia J. Johnston et al.   CELL

The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling

(2015) Liam C. Hunt et al.   GENES & DEVELOPMENT

Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy

(2015) Giulia Milan et al.   Nature Communications

Acetylation of MAT IIα represses tumour cell growth and is decreased in human hepatocellular cancer

(2015) Hong-Bin Yang et al.   Nature Communications

Autoubiquitination of the 26S Proteasome on Rpn13 Regulates Breakdown of Ubiquitin Conjugates

(2014) H. C. Besche et al.   EMBO JOURNAL

Proteasome dysfunction induces muscle growth defects and protein aggregation

(2014) Y. Kitajima et al.   JOURNAL OF CELL SCIENCE

CrossTalk opposing view: The dominant mechanism causing disuse muscle atrophy is proteolysis

(2014) Michael B. Reid et al.   JOURNAL OF PHYSIOLOGY-LONDON

JUMP: A Tag-based Database Search Tool for Peptide Identification with High Sensitivity and Accuracy

(2014) Xusheng Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Autophagy Impairment in Muscle Induces Neuromuscular Junction Degeneration and Precocious Aging

(2014) Silvia Carnio et al.   Cell Reports

Intertissue Control of the Nucleolus via a Myokine-Dependent Longevity Pathway

(2014) Fabio Demontis et al.   Cell Reports

The influence of skeletal muscle on systemic aging and lifespan

(2013) Fabio Demontis et al.   AGING CELL

Maintenance of muscle mass and load-induced growth in Muscle RING Finger 1 null mice with age

(2013) Darren T. Hwee et al.   AGING CELL

Signalling pathways regulating muscle mass in ageing skeletal muscle. The role of the IGF1-Akt-mTOR-FoxO pathway

(2013) M. Sandri et al.   BIOGERONTOLOGY

Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy

(2013) Perrine Castets et al.   Cell Metabolism

Mechanisms of muscle growth and atrophy in mammals andDrosophila

(2013) Rosanna Piccirillo et al.   DEVELOPMENTAL DYNAMICS

Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models

(2013) F. Demontis et al.   Disease Models & Mechanisms

Effect of myonuclear number and mitochondrial fusion on Drosophila indirect flight muscle organization and size

(2013) Mamta Rai et al.   EXPERIMENTAL CELL RESEARCH

Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth

(2013) Ruiting Lin et al.   MOLECULAR CELL

Whole-mount immunostaining of Drosophila skeletal muscle

(2013) Liam C Hunt et al.   Nature Protocols

UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy

(2013) T. Tasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular and molecular mechanisms of muscle atrophy

(2012) P. Bonaldo et al.   Disease Models & Mechanisms

Inducible Cre transgenic mouse strain for skeletal muscle-specific gene targeting

(2012) John J McCarthy et al.   Skeletal Muscle

Regulation of Endocytic Sorting by ESCRT–DUB-Mediated Deubiquitination

(2011) Michelle H. Wright et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Reversing Cachexia

(2010) Michael J. Tisdale   CELL

Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival

(2010) Xiaolan Zhou et al.   CELL

FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging

(2010) Fabio Demontis et al.   CELL

CF2 Represses Actin 88F Gene Expression and Maintains Filament Balance during Indirect Flight Muscle Development in Drosophila

(2010) Kathleen M. Gajewski et al.   PLoS One

Isolation of Mammalian 26S Proteasomes and p97/VCP Complexes Using the Ubiquitin-like Domain from HHR23B Reveals Novel Proteasome-Associated Proteins†

(2009) Henrike C. Besche et al.   BIOCHEMISTRY

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila

(2009) F. Demontis et al.   DEVELOPMENT

Systematical Optimization of Reverse-Phase Chromatography for Shotgun Proteomics

(2009) Ping Xu et al.   JOURNAL OF PROTEOME RESEARCH

Age-related differences in the dose-response relationship of muscle protein synthesis to resistance exercise in young and old men

(2008) Vinod Kumar et al.   JOURNAL OF PHYSIOLOGY-LONDON

CHIP Deficiency Decreases Longevity, with Accelerated Aging Phenotypes Accompanied by Altered Protein Quality Control

(2008) J.-N. Min et al.   MOLECULAR AND CELLULAR BIOLOGY

Sigma's Non-specific Protease Activity Assay - Casein as a Substrate

(2008) Carrie Cupp-Enyard   Jove-Journal of Visualized Experiments