CrossTalk opposing view: The dominant mechanism causing disuse muscle atrophy is proteolysis

Substantial skeletal muscle loss occurs during only 5 days of disuse

(2013) B. T. Wall et al.   Acta Physiologica

Disuse-induced muscle wasting

(2013) Sue C. Bodine   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Calpain and caspase-3 play required roles in immobilization-induced limb muscle atrophy

(2013) Erin E. Talbert et al.   JOURNAL OF APPLIED PHYSIOLOGY

Diaphragm Muscle Thinning in Patients Who Are Mechanically Ventilated

(2012) Horiana B. Grosu et al.   CHEST

Cross-talk between the calpain and caspase-3 proteolytic systems in the diaphragm during prolonged mechanical ventilation

(2012) W. Bradley Nelson et al.   CRITICAL CARE MEDICINE

The time course of the adaptations of human muscle proteome to bed rest and the underlying mechanisms

(2012) Lorenza Brocca et al.   JOURNAL OF PHYSIOLOGY-LONDON

Aging Affects the Transcriptional Regulation of Human Skeletal Muscle Disuse Atrophy

(2012) Charlotte Suetta et al.   PLoS One

Oxidative stress, apoptosis, and proteolysis in skeletal muscle repair after unloading

(2010) Tina Andrianjafiniony et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mechanical Ventilation–induced Diaphragm Disuse in Humans Triggers Autophagy

(2010) Sabah N. A. Hussain et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Increased Proteolysis, Myosin Depletion, and Atrophic AKT-FOXO Signaling in Human Diaphragm Disuse

(2010) Sanford Levine et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effects of 3 days unloading on molecular regulators of muscle size in humans

(2010) T. Gustafsson et al.   JOURNAL OF APPLIED PHYSIOLOGY

Forty-eight hours of unloading and 24 h of reloading lead to changes in global gene expression patterns related to ubiquitination and oxidative stress in humans

(2010) Kimberly A. Reich et al.   JOURNAL OF APPLIED PHYSIOLOGY

Facts, noise and wishful thinking: muscle protein turnover in aging and human disuse atrophy

(2010) M. J. Rennie et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Proteolysis activation and proteome alterations in murine skeletal muscle submitted to 1 week of hindlimb suspension

(2009) Rita Ferreira et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Limb Immobilization Induces a Coordinate Down-Regulation of Mitochondrial and Other Metabolic Pathways in Men and Women

(2009) Arkan Abadi et al.   PLoS One

Hsp70 overexpression inhibits NF-κB and Foxo3a transcriptional activities and prevents skeletal muscle atrophy

(2008) Sarah M. Senf et al.   FASEB JOURNAL

Skeletal muscle proteolysis in response to short-term unloading in humans

(2008) Per A. Tesch et al.   JOURNAL OF APPLIED PHYSIOLOGY

Rapid Disuse Atrophy of Diaphragm Fibers in Mechanically Ventilated Humans

(2008) Sanford Levine et al.   NEW ENGLAND JOURNAL OF MEDICINE