The Impact of Estrogen and Estrogen-Like Molecules in Neurogenesis and Neurodegeneration: Beneficial or Harmful?

The critical period for neuroprotection by estrogen replacement therapy and the potential underlying mechanisms

(2020) Hang Guo et al.   Current Neuropharmacology

Prolactin, Estradiol and Testosterone Differentially Impact Human Hippocampal Neurogenesis in an In Vitro Model

(2020) Demelza M. Smeeth et al.   NEUROSCIENCE

Regulation of BDNF-TrkB Signaling and Potential Therapeutic Strategies for Parkinson’s Disease

(2020) Jin   Journal of Clinical Medicine

FSH for the Treatment of Male Infertility

(2020) Livio Casarini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Effect of Estrogen Replacement Therapy on Alzheimer's Disease and Parkinson's Disease in Postmenopausal Women: A Meta-Analysis

(2020) Yu-jia Song et al.   Frontiers in Neuroscience

Mechanistic model of hormonal contraception

(2020) A. Armean Wright et al.   PLoS Computational Biology

GPER1 Signaling Initiates Migration of Female V-SVZ-Derived Cells

(2020) Iris Haumann et al.   iScience

Continuous Exposure of Breast Cancer Cells to Tamoxifen Upregulates GPER-1 and Increases Cell Proliferation

(2020) Luis Molina et al.   Frontiers in Endocrinology

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

(2019) Elena P. Moreno-Jiménez et al.   NATURE MEDICINE

KCC2 Manipulation Alters Features of Migrating Interneurons in Ferret Neocortex

(2019) F T Djankpa et al.   CEREBRAL CORTEX

Amyloid Beta and MicroRNAs in Alzheimer’s Disease

(2019) Nnana Amakiri et al.   Frontiers in Neuroscience

G protein-coupled estrogen receptor 1 negatively regulates the proliferation of mouse-derived neural stem/progenitor cells via extracellular signal-regulated kinase pathway

(2019) Jun Zhong et al.   BRAIN RESEARCH

Neurotoxicity of BPA, BPS, and BPB for the hippocampal cell line (HT-22): An implication for the replacement of BPA in plastics

(2019) Qihua Pang et al.   CHEMOSPHERE

Decision points for individualized hormonal stimulation with recombinant gonadotropins for treatment of women with infertility

(2019) Bruno Lunenfeld et al.   GYNECOLOGICAL ENDOCRINOLOGY

The Controversial History of Hormone Replacement Therapy

(2019) Angelo Cagnacci et al.   Medicina-Lithuania

Estrogen: The necessary evil for human health, and ways to tame it

(2018) Seema Patel et al.   BIOMEDICINE & PHARMACOTHERAPY

Menopausal hormone therapy: a better and safer future

(2018) D. A. Davey   CLIMACTERIC

Sex differences in Alzheimerʼs disease

(2018) Keith R. Laws et al.   CURRENT OPINION IN PSYCHIATRY

Extranuclear-initiated estrogenic actions of endocrine disrupting chemicals: Is there toxicology beyond paracelsus?

(2018) Angel Nadal et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Vitamin D Improves Neurogenesis and Cognition in a Mouse Model of Alzheimer’s Disease

(2018) Maria Morello et al.   MOLECULAR NEUROBIOLOGY

Membrane-initiated estrogen signaling via Gq-coupled GPCR in the central nervous system

(2018) Gwyndolin Vail et al.   STEROIDS

Estradiol and the Development of the Cerebral Cortex: An Unexpected Role?

(2018) Matthew C. S. Denley et al.   Frontiers in Neuroscience

The Effects of Low-Dose Bisphenol A and Bisphenol F on Neural Differentiation of a Fetal Brain-Derived Neural Progenitor Cell Line

(2018) Yuki Fujiwara et al.   Frontiers in Endocrinology

Factors that influence adult neurogenesis as potential therapy

(2018) Belal Shohayeb et al.   Translational Neurodegeneration

Sensitive neurotoxicity assessment of bisphenol A using double immunocytochemistry of DCX and MAP2

(2018) Jung-Hyun Cho et al.   ARCHIVES OF PHARMACAL RESEARCH

Brain-derived neurotrophic factor and epilepsy: a systematic review

(2018) Lorenzo Iughetti et al.   NEUROPEPTIDES

Possible role of phytoestrogens in breast cancer via GPER-1/GPR30 signaling

(2018) Luis Molina et al.   CLINICAL SCIENCE

Neural Progenitor Cell Terminology

(2018) Verónica Martínez-Cerdeño et al.   Frontiers in Neuroanatomy

GPER-1/GPR30 a novel estrogen receptor sited in the cell membrane: therapeutic coupling to breast cancer

(2017) Luis Molina et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Estrogens regulate life and death in mitochondria

(2017) Carolyn M. Klinge   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Role of estrogen and levodopa in 1-methyl-4-pheny-l-1, 2, 3, 6-tetrahydropyridine (mptp)-induced cognitive deficit in Parkinsonian ovariectomized mice model: A comparative study

(2017) Satyndra Kumar Yadav et al.   JOURNAL OF CHEMICAL NEUROANATOMY

PKA-GSK3β and β-Catenin Signaling Play a Critical Role in Trans-Resveratrol Mediated Neuronal Differentiation in Human Cord Blood Stem Cells

(2017) S Jahan et al.   MOLECULAR NEUROBIOLOGY

Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer’s disease by compromising hippocampal inhibition

(2017) Carolyn Hollands et al.   Molecular Neurodegeneration

Estrogens as neuroprotectants: Estrogenic actions in the context of cognitive aging and brain injury

(2017) E.B. Engler-Chiurazzi et al.   PROGRESS IN NEUROBIOLOGY

Role of Estrogen and Other Sex Hormones in Brain Aging. Neuroprotection and DNA Repair

(2017) Sandra Zárate et al.   Frontiers in Aging Neuroscience

Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria

(2016) Bruno Dubois et al.   Alzheimers & Dementia

Estrogens, Neuroinflammation, and Neurodegeneration

(2016) Alessandro Villa et al.   ENDOCRINE REVIEWS

GPR30 Promotes Prostate Stromal Cell Activation via Suppression of ERα Expression and Its Downstream Signaling Pathway

(2016) Bona Jia et al.   ENDOCRINOLOGY

Dynamin-related Protein 1 Inhibition Mitigates Bisphenol A-mediated Alterations in Mitochondrial Dynamics and Neural Stem Cell Proliferation and Differentiation

(2016) Swati Agarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estrogen modulation of calretinin and BDNF expression in midbrain dopaminergic neurons of ovariectomised mice

(2016) Hongliang Yi et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Nudging oligodendrocyte intrinsic signaling to remyelinate and repair: Estrogen receptor ligand effects

(2016) Anna J. Khalaj et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

GPER, IGF-IR, and EGFR transduction signaling are involved in stimulatory effects of zinc in breast cancer cells and cancer-associated fibroblasts

(2016) Assunta Pisano et al.   MOLECULAR CARCINOGENESIS

Ovarian steroids regulate gene expression in the dorsal raphe of old female macaques

(2016) Cynthia L. Bethea et al.   NEUROBIOLOGY OF AGING

Tamoxifen promotes differentiation of oligodendrocyte progenitors in vitro

(2016) H.E. Barratt et al.   NEUROSCIENCE

Regulation of proapoptotic proteins Bak1 and p53 by miR-125b in an experimental model of Alzheimer's disease: Protective role of 17β-estradiol

(2016) F. Micheli et al.   NEUROSCIENCE LETTERS

Exosomes as Novel Regulators of Adult Neurogenic Niches

(2016) Luis Federico Bátiz et al.   Frontiers in Cellular Neuroscience

Tamoxifen accelerates the repair of demyelinated lesions in the central nervous system

(2016) Ginez A. Gonzalez et al.   Scientific Reports

Analyzing dendritic spine pathology in Alzheimer’s disease: problems and opportunities

(2015) Mario M. Dorostkar et al.   ACTA NEUROPATHOLOGICA

Classic and novel stem cell niches in brain homeostasis and repair

(2015) Ruihe Lin et al.   BRAIN RESEARCH

Finding the Roots of Adult Neurogenesis

(2015) Mazen A. Kheirbek   CELL

It Takes a Village: Constructing the Neurogenic Niche

(2015) Christopher S. Bjornsson et al.   DEVELOPMENTAL CELL

Bisphenol-A exposure during adolescence leads to enduring alterations in cognition and dendritic spine density in adult male and female rats

(2015) Rachel E. Bowman et al.   HORMONES AND BEHAVIOR

Bisphenol-A Mediated Inhibition of Hippocampal Neurogenesis Attenuated by Curcumin via Canonical Wnt Pathway

(2015) Shashi Kant Tiwari et al.   MOLECULAR NEUROBIOLOGY

Proliferation control in neural stem and progenitor cells

(2015) Catarina C. F. Homem et al.   NATURE REVIEWS NEUROSCIENCE

Estrogen plus progestin increase superoxide dismutase and total antioxidant capacity in postmenopausal women

(2014) T. C. Unfer et al.   CLIMACTERIC

Dysregulation of Neurotrophic and Haematopoietic Growth Factors in Alzheimer’s Disease: From Pathophysiology to Novel Treatment Strategies

(2014) Kateryna Sopova et al.   Current Alzheimer Research

Bisphenol a regulates the estrogen receptor alpha signaling in developing hippocampus of male rats through estrogen receptor

(2014) Xiao-Bin Xu et al.   HIPPOCAMPUS

Pharmacokinetics of Equol, a Soy Isoflavone Metabolite, Changes with the Form of Equol (Dietary versus Intestinal Production) in Ovariectomized Rats

(2014) LeeCole L. Legette et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Inhibitory Effects of Bisphenol-A on Neural Stem Cells Proliferation and Differentiation in the Rat Brain Are Dependent on Wnt/β-Catenin Pathway

(2014) Shashi Kant Tiwari et al.   MOLECULAR NEUROBIOLOGY

Bisphenol-A Impairs Myelination Potential During Development in the Hippocampus of the Rat Brain

(2014) Shashi Kant Tiwari et al.   MOLECULAR NEUROBIOLOGY

Regulation and Function of Adult Neurogenesis: From Genes to Cognition

(2014) James B. Aimone et al.   PHYSIOLOGICAL REVIEWS

Investigation of the Effects of Subchronic Low Dose Oral Exposure to Bisphenol A (BPA) and Ethinyl Estradiol (EE) on Estrogen Receptor Expression in the Juvenile and Adult Female Rat Hypothalamus

(2014) Meghan E. Rebuli et al.   TOXICOLOGICAL SCIENCES

Greater Monoamine Oxidase A Binding in Perimenopausal Age as Measured With Carbon 11–Labeled Harmine Positron Emission Tomography

(2014) Paraskevi Vivien Rekkas et al.   JAMA Psychiatry

Adolescent exposure to Bisphenol-A increases anxiety and sucrose preference but impairs spatial memory in rats independent of sex

(2013) Samantha Diaz Weinstein et al.   BRAIN RESEARCH

Molecular biomarkers as potential targets for therapeutic strategies in human testicular germ cell tumors: An overview

(2013) Paolo Chieffi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Chroman-like cyclic prenylflavonoids promote neuronal differentiation and neurite outgrowth and are neuroprotective

(2013) Eleni Oberbauer et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

17β-Estradiol increases expression of the oxidative stress response and DNA repair protein apurinic endonuclease (Ape1) in the cerebral cortex of female mice following hypoxia

(2013) Alicia K. Dietrich et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Estrogen receptor beta in breast cancer

(2013) Lars-Arne Haldosén et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Estrogen receptor β ligand therapy activates PI3K/Akt/mTOR signaling in oligodendrocytes and promotes remyelination in a mouse model of multiple sclerosis

(2013) Shalini Kumar et al.   NEUROBIOLOGY OF DISEASE

BDNF and memory processing

(2013) Pedro Bekinschtein et al.   NEUROPHARMACOLOGY

Trophic factor and hormonal regulation of neurite outgrowth in sensory neuron-like 50B11 cells

(2013) Aritra Bhattacherjee et al.   NEUROSCIENCE LETTERS

Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on theKcc2promoter

(2013) Michele Yeo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estrogen synthesis and signaling pathways during aging: from periphery to brain

(2013) Jie Cui et al.   TRENDS IN MOLECULAR MEDICINE

Base Excision Repair

(2013) H. E. Krokan et al.   Cold Spring Harbor Perspectives in Biology

Exploring the Contribution of Estrogen to Amyloid-Beta Regulation: A Novel Multifactorial Computational Modeling Approach

(2013) Thomas J. Anastasio   Frontiers in Pharmacology

Sex hormones modulate circulating antioxidant enzymes: Impact of estrogen therapy

(2013) Francesco Bellanti et al.   Redox Biology

Bioavailability and Pharmacokinetics of Genistein: Mechanistic Studies on its ADME

(2012) Zhen Yang et al.   Anti-Cancer Agents in Medicinal Chemistry

Induction of cell proliferation and survival genes by estradiol-repressed microRNAs in breast cancer cells

(2012) Xinfeng Yu et al.   BMC CANCER

Resveratrol Inhibits the Proliferation of Neural Progenitor Cells and Hippocampal Neurogenesis

(2012) Hee Ra Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous Ovarian Hormones Affect Mitochondrial Efficiency in Cerebral Endothelium via Distinct Regulation of PGC-1 Isoforms

(2012) Martin F Kemper et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Multifaces of neuropeptide Y in the brain – Neuroprotection, neurogenesis and neuroinflammation

(2012) J.O. Malva et al.   NEUROPEPTIDES

Interactions between estradiol, BDNF and dendritic spines in promoting memory

(2012) V. Luine et al.   NEUROSCIENCE

Rapid Direct Action of Estradiol in GnRH Neurons: Findings and Implications

(2012) Brian P. Kenealy et al.   Frontiers in Endocrinology

Estrogens in the breast tissue: a systematic review

(2011) Lusine Yaghjyan et al.   CANCER CAUSES & CONTROL

Biological effects and bioaccumulation of steroidal and phenolic endocrine disrupting chemicals in high-back crucian carp exposed to wastewater treatment plant effluents

(2011) Jingliang Liu et al.   ENVIRONMENTAL POLLUTION

17β-Estradiol Protects Dopaminergic Neurons in Organotypic Slice of Mesencephalon by MAPK-Mediated Activation of Anti-apoptosis Gene BCL2

(2011) Shuyan Wang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Study of DNA damage via the comet assay and base excision repair activities in rat brain neurons and astrocytes during aging

(2011) Umakanta Swain et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Effects of aromatase inhibition versus gonadectomy on hippocampal complex amyloid pathology in triple transgenic mice

(2011) Cassia R. Overk et al.   NEUROBIOLOGY OF DISEASE

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

(2011) Guo-li Ming et al.   NEURON

Reproductive Hormones and the Menopause Transition

(2011) Nanette Santoro et al.   OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA

The complexity of cardiolipin in health and disease

(2011) Steven M. Claypool et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling

(2010) Anatoly A. Starkov   Annals of the New York Academy of Sciences

Role of estrogen receptors in pro-oxidative and anti-oxidative actions of estrogens: A perspective

(2010) Sukhdeep Kumar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Oestrogen receptor β ligand: a novel treatment to enhance endogenous functional remyelination

(2010) Daniel K. Crawford et al.   BRAIN

Genistein reduced the neural apoptosis in the brain of ovariectomised rats by modulating mitochondrial oxidative stress

(2010) Yan-Hong Huang et al.   BRITISH JOURNAL OF NUTRITION

Bisphenol A Exposure during Pregnancy Disrupts Glucose Homeostasis in Mothers and Adult Male Offspring

(2010) Paloma Alonso-Magdalena et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Differences in sensitivity but not selectivity of xenoestrogen binding to alligator versus human estrogen receptor alpha

(2010) Cynthia V. Rider et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Estrogen Stimulates Proliferation and Differentiation of Neural Stem/Progenitor Cells through Different Signal Transduction Pathways

(2010) Makiko Okada et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

trans-Resveratrol as A Neuroprotectant

(2010) Ellen L. Robb et al.   MOLECULES

Estrogen Actions in the Brain and the Basis for Differential Action in Men and Women: A Case for Sex-Specific Medicines

(2010) G. E. Gillies et al.   PHARMACOLOGICAL REVIEWS

Estrogen Receptor β-Selective Agonists Stimulate Calcium Oscillations in Human and Mouse Embryonic Stem Cell-Derived Neurons

(2010) Lili Zhang et al.   PLoS One

Endocrine disruptors in bottled mineral water: total estrogenic burden and migration from plastic bottles

(2009) Martin Wagner et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Effect of caloric restriction on base-excision repair (BER) in the aging rat brain

(2009) Glen E. Kisby et al.   EXPERIMENTAL GERONTOLOGY

Protective actions of sex steroid hormones in Alzheimer’s disease

(2009) Christian J. Pike et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Potencies of Bisphenol a on the Neuronal Differentiation and Hippocampal Neurogenesis

(2009) Keunho Kim et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Premature menopause or early menopause: Long-term health consequences

(2009) Lynne T. Shuster et al.   MATURITAS

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

KCC2 Expression Promotes the Termination of Cortical Interneuron Migration in a Voltage-Sensitive Calcium-Dependent Manner

(2009) Dante Bortone et al.   NEURON

Estrogen action: A historic perspective on the implications of considering alternative approaches

(2009) Elwood V. Jensen et al.   PHYSIOLOGY & BEHAVIOR

Transcriptional Mutagenesis Induced by 8-Oxoguanine in Mammalian Cells

(2009) Damien Brégeon et al.   PLoS Genetics

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Neural Stem Cells Confer Unique Pinwheel Architecture to the Ventricular Surface in Neurogenic Regions of the Adult Brain

(2008) Zaman Mirzadeh et al.   Cell Stem Cell

Runx2 Regulates G Protein-coupled Signaling Pathways to Control Growth of Osteoblast Progenitors

(2008) Nadiya M. Teplyuk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Growth Hormone Treatment on Lymphocyte Functions in Old Male Rats

(2008) Isabel Baeza et al.   NEUROIMMUNOMODULATION

Bisphenol A prevents the synaptogenic response to estradiol in hippocampus and prefrontal cortex of ovariectomized nonhuman primates

(2008) C. Leranth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippocampal mitochondrial dysfunction in rat aging

(2007) Ana Navarro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

New Interneurons in the Adult Neocortex: Small, Sparse, but Significant?

(2007) Heather A. Cameron et al.   BIOLOGICAL PSYCHIATRY

Estradiol-17β-Induced Human Neural Progenitor Cell Proliferation Is Mediated by an Estrogen Receptor β-Phosphorylated Extracellularly Regulated Kinase Pathway

(2007) Jun Ming Wang et al.   ENDOCRINOLOGY

Contribution of estrogen receptors alpha and beta to the effects of estradiol in the brain

(2007) M. Morissette et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY